8SOQ
| S127A variant of LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with authentic substrate NaAD | Descriptor: | MAGNESIUM ION, NICOTINIC ACID ADENINE DINUCLEOTIDE, Pyridinium-3,5-biscarboxylic acid mononucleotide synthase | Authors: | Chatterjee, S, Rankin, J.A, Hu, J, Hausinger, R.P. | Deposit date: | 2023-04-29 | Release date: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of the LarB-Substrate Complex and Identification of a Reaction Intermediate during Nickel-Pincer Nucleotide Cofactor Biosynthesis. Biochemistry, 62, 2023
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8STD
| S127A variant of LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with authentic substrate NaAD and soaked with CS2 | Descriptor: | MAGNESIUM ION, NICOTINIC ACID ADENINE DINUCLEOTIDE, Pyridinium-3,5-biscarboxylic acid mononucleotide synthase | Authors: | Chatterjee, S, Rankin, J.A, Hu, J, Hausinger, R.P. | Deposit date: | 2023-05-10 | Release date: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structure of the LarB-Substrate Complex and Identification of a Reaction Intermediate during Nickel-Pincer Nucleotide Cofactor Biosynthesis. Biochemistry, 62, 2023
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7XNE
| Crystal structure of CBP bromodomain liganded with Y08284 | Descriptor: | CREB-binding protein, GLYCEROL, N-[3-(1-cyclopropylpyrazol-4-yl)-2-fluoranyl-5-[(1S)-1-oxidanylethyl]phenyl]-3-ethanoyl-7-methoxy-indolizine-1-carboxamide | Authors: | Xiang, Q, Wang, C, Wu, T, Zhang, C, Hu, Q, Luo, G, Hu, J, Zhuang, X, Zou, L, Shen, H, Wu, X, Zhang, Y, Kong, X, Xu, Y. | Deposit date: | 2022-04-28 | Release date: | 2022-07-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer. J.Med.Chem., 65, 2022
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3PMR
| Crystal Structure of E2 domain of Human Amyloid Precursor-Like Protein 1 | Descriptor: | Amyloid-like protein 1, PHOSPHATE ION | Authors: | Lee, S, Xue, Y, Hu, J, Wang, Y, Liu, X, Demeler, B, Ha, Y. | Deposit date: | 2010-11-17 | Release date: | 2011-06-01 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization. Biochemistry, 50, 2011
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4L1M
| Structure of the first RCC1-like domain of HERC2 | Descriptor: | E3 ubiquitin-protein ligase HERC2, SULFATE ION, UNKNOWN ATOM OR ION | Authors: | Tempel, W, Khan, M.B, Dong, A, Hu, J, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | Deposit date: | 2013-06-03 | Release date: | 2013-07-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the first RCC1-like domain of HERC2 TO BE PUBLISHED
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3NYJ
| Crystal Structure Analysis of APP E2 domain | Descriptor: | Amyloid beta A4 protein, OSMIUM ION | Authors: | Ha, Y, Hu, J, Lee, S, Liu, X. | Deposit date: | 2010-07-15 | Release date: | 2011-06-01 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization. Biochemistry, 50, 2011
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4KFW
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4KFV
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4RXX
| Crystal Structure of the N-terminal Domain of Human Ubiquitin Specific Protease 38 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, UNKNOWN ATOM OR ION, ... | Authors: | Dong, A, Shen, L, Hu, J, Li, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | Deposit date: | 2014-12-12 | Release date: | 2015-01-21 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Crystal Structure of the N-terminal Domain of Human Ubiquitin Specific Protease 38 to be published
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5TSB
| Crystal structure of the Zrt-/Irt-like protein from Bordetella bronchiseptica with bound Cd2+ | Descriptor: | CADMIUM ION, Membrane protein | Authors: | Zhang, T, Fellner, M, Sui, D, Liu, J, Hu, J. | Deposit date: | 2016-10-28 | Release date: | 2017-09-20 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway. Sci Adv, 3, 2017
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5TSA
| Crystal structure of the Zrt-/Irt-like protein from Bordetella bronchiseptica with bound Zn2+ | Descriptor: | CADMIUM ION, Membrane protein, ZINC ION | Authors: | Zhang, T, Fellner, M, Sui, D, Liu, J, Hu, J. | Deposit date: | 2016-10-28 | Release date: | 2017-09-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway. Sci Adv, 3, 2017
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7WNT
| RNase J from Mycobacterium tuberculosis | Descriptor: | Ribonuclease J, ZINC ION | Authors: | Li, J, Bao, L, Hu, J, Zhan, B, Li, Z. | Deposit date: | 2022-01-19 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Structural ans functional study of RNase J from Mycobacterium tuberculosis To Be Published
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7WNU
| Mycobacterium tuberculosis Rnase J complex with 7nt RNA | Descriptor: | RNA (5'-R(P*AP*AP*AP*AP*AP*AP*A)-3'), Ribonuclease J, ZINC ION | Authors: | Li, J, Hu, J, Bao, L, Zhan, B, Li, Z. | Deposit date: | 2022-01-19 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural ans functional study of RNase J from Mycobacterium tuberculosis To Be Published
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5V2Z
| Ethylene forming enzyme in complex with manganese, 2-oxoadipic acid and L-arginine | Descriptor: | 2-OXOADIPIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ARGININE, ... | Authors: | Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. | Deposit date: | 2017-03-06 | Release date: | 2017-08-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.23 Å) | Cite: | Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist. J. Am. Chem. Soc., 139, 2017
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5V2V
| Ethylene forming enzyme in complex with nickel | Descriptor: | 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, NICKEL (II) ION | Authors: | Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. | Deposit date: | 2017-03-06 | Release date: | 2017-08-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.04 Å) | Cite: | Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist. J. Am. Chem. Soc., 139, 2017
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5V2Y
| Ethylene forming enzyme in complex with manganese, 2-oxoglutarate and L-arginine | Descriptor: | 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ARGININE, ... | Authors: | Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. | Deposit date: | 2017-03-06 | Release date: | 2017-08-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.428 Å) | Cite: | Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist. J. Am. Chem. Soc., 139, 2017
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5V2X
| Ethylene forming enzyme in complex with manganese and 2-oxoglutarate | Descriptor: | 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, MANGANESE (II) ION | Authors: | Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. | Deposit date: | 2017-03-06 | Release date: | 2017-08-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.847 Å) | Cite: | Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist. J. Am. Chem. Soc., 139, 2017
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5V2U
| Ethylene forming enzyme apo form | Descriptor: | 2-oxoglutarate-dependent ethylene/succinate-forming enzyme | Authors: | Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. | Deposit date: | 2017-03-06 | Release date: | 2017-08-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.058 Å) | Cite: | Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist. J. Am. Chem. Soc., 139, 2017
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5V32
| Ethylene forming enzyme in complex with manganese and malic acid | Descriptor: | 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, D-MALATE, MANGANESE (II) ION | Authors: | Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. | Deposit date: | 2017-03-06 | Release date: | 2017-08-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.486 Å) | Cite: | Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist. J. Am. Chem. Soc., 139, 2017
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5V34
| Ethylene forming enzyme in complex with manganese, malic acid and L-arginine | Descriptor: | 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ARGININE, D-MALATE, ... | Authors: | Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. | Deposit date: | 2017-03-06 | Release date: | 2017-08-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist. J. Am. Chem. Soc., 139, 2017
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5V31
| Ethylene forming enzyme in complex with manganese and L-arginine | Descriptor: | 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ARGININE, MANGANESE (II) ION | Authors: | Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. | Deposit date: | 2017-03-06 | Release date: | 2017-08-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist. J. Am. Chem. Soc., 139, 2017
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5V2T
| Ethylene forming enzyme in complex with manganese and tartrate | Descriptor: | 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, L(+)-TARTARIC ACID, MANGANESE (II) ION | Authors: | Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. | Deposit date: | 2017-03-06 | Release date: | 2017-08-16 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (1.227 Å) | Cite: | Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist. J. Am. Chem. Soc., 139, 2017
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5VKA
| Ethylene forming enzyme in complex with manganese, 2-oxoglutarate and N-omega-hydroxy-L-arginine | Descriptor: | 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, MANGANESE (II) ION, ... | Authors: | Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. | Deposit date: | 2017-04-21 | Release date: | 2017-08-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.169 Å) | Cite: | Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist. J. Am. Chem. Soc., 139, 2017
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5VKB
| Ethylene forming enzyme in complex with manganese, 2-oxoglutarate and argininamide | Descriptor: | 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ARGININEAMIDE, ... | Authors: | Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. | Deposit date: | 2017-04-21 | Release date: | 2017-08-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.139 Å) | Cite: | Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist. J. Am. Chem. Soc., 139, 2017
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2K4K
| Solution structure of GSP13 from Bacillus subtilis | Descriptor: | General stress protein 13 | Authors: | Yu, W, Yu, B, Hu, J, Jin, C, Xia, B. | Deposit date: | 2008-06-13 | Release date: | 2009-05-12 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Solution structure of GSP13 from Bacillus subtilis exhibits an S1 domain related to cold shock proteins. J.Biomol.Nmr, 43, 2009
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