8SOQ

S127A variant of LarB, a carboxylase/hydrolase involved in synthesis of the cofactor for lactate racemase, in complex with authentic substrate NaAD

Summary for 8SOQ

Entry DOI	10.2210/pdb8soq/pdb
Descriptor	Pyridinium-3,5-biscarboxylic acid mononucleotide synthase, MAGNESIUM ION, NICOTINIC ACID ADENINE DINUCLEOTIDE (3 entities in total)
Functional Keywords	carboxylase, hydrolase, lyase (carbon-carbon), lyase
Biological source	Lactiplantibacillus plantarum WCFS1
Total number of polymer chains	6
Total formula weight	162462.59
Authors	Chatterjee, S.,Rankin, J.A.,Hu, J.,Hausinger, R.P. (deposition date: 2023-04-29, release date: 2023-12-27)
Primary citation	Chatterjee, S.,Nevarez, J.L.,Rankin, J.A.,Hu, J.,Hausinger, R.P. Structure of the LarB-Substrate Complex and Identification of a Reaction Intermediate during Nickel-Pincer Nucleotide Cofactor Biosynthesis. Biochemistry, 62:3096-3104, 2023 Cited by PubMed: 37831946 DOI: 10.1021/acs.biochem.3c00242 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation