7SJN
 
 | | HtrA1:Fab15H6.v4 complex | | 分子名称: | Fab15H6.v4 Heavy Chain, Fab15H6.v4 Light Chain, Serine protease HTRA1 | | 著者 | Gerhardy, S, Green, E, Estevez, A, Arthur, C.P, Ultsch, M, Rohou, A, Kirchhofer, D. | | 登録日 | 2021-10-18 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-09-21 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration.
Nat Commun, 13, 2022
|
|
7SJO
 | | HtrA1S328A:Fab15H6.v4 complex | | 分子名称: | Fab15H6.v4 Heavy Chain, Fab15H6.v4 Light Chain, Serine protease HTRA1 | | 著者 | Gerhardy, S, Green, E, Estevez, A, Arthur, C.P, Ultsch, M, Rohou, A, Kirchhofer, D. | | 登録日 | 2021-10-18 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-09-21 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration.
Nat Commun, 13, 2022
|
|
7SJP
 | |
7SJM
 | | anti-HtrA1 Fab15H6.v4 | | 分子名称: | GLYCEROL, Heavy Chain, Light Chain, ... | | 著者 | Ultsch, M.H, Gerhardy, S. | | 登録日 | 2021-10-18 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration.
Nat Commun, 13, 2022
|
|
6G52
 | | CRYSTAL STRUCTURE OF THE CNMP BINDING DOMAIN OF THE MAGNESIUM TRANSPORTER CNNM4 | | 分子名称: | Metal transporter CNNM4 | | 著者 | Gimenez, P, Oyenarte, I, Hardy, S, Zubillaga, M, Merino, N, Blanco, F.J, Siliqi, D, Tremblay, M, Muller, D, Martinez-Cruz, L.A. | | 登録日 | 2018-03-28 | | 公開日 | 2019-04-10 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (3.691 Å) | | 主引用文献 | Structural Insights into the Intracellular Region of the Human Magnesium Transport Mediator CNNM4.
Int J Mol Sci, 20, 2019
|
|
5LXQ
 | | Structure of PRL-1 in complex with the Bateman domain of CNNM2 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Metal transporter CNNM2, Protein tyrosine phosphatase type IVA 1, ... | | 著者 | GIMENEZ-Mascarell, P, Oyenarte, I, Hardy, S, Breiderhoff, T, Stuiver, M, Kostantin, E, Diercks, T, Pey, A.L, Ereno-ORBEA, J, Martinez-Chantar, M.L, Khalaf-Nazzal, R, Claverie-Martin, F, Muller, D, Tremblay, M, Martinez-Cruz, L.A. | | 登録日 | 2016-09-22 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.335 Å) | | 主引用文献 | Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.
J. Biol. Chem., 292, 2017
|
|
5MMZ
 | | Structure of PRL-1 in complex with the Bateman domain of CNNM2 | | 分子名称: | Metal transporter CNNM2, Protein tyrosine phosphatase type IVA 1 | | 著者 | Gimenez-Mascarell, P, Oyenarte, I, Hardy, S, Breiderhoff, T, Stuiver, M, Kostantin, E, Diercks, T, Pey, A.L, Ereno-Orbea, J, Martinez-Chantar, M.L, Khalaf-Nazzal, R, Claverie-Martin, F, Muller, D, Tremblay, M.L, Martinez-Cruz, L.A. | | 登録日 | 2016-12-12 | | 公開日 | 2016-12-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.
J. Biol. Chem., 292, 2017
|
|
6FAI
 | | Structure of a eukaryotic cytoplasmic pre-40S ribosomal subunit | | 分子名称: | 20S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | | 著者 | Scaiola, A, Pena, C, Weisser, M, Boehringer, D, Leibundgut, M, Klingauf-Nerurkar, P, Gerhardy, S, Panse, V.G, Ban, N. | | 登録日 | 2017-12-15 | | 公開日 | 2018-02-28 | | 最終更新日 | 2018-04-11 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of a eukaryotic cytoplasmic pre-40S ribosomal subunit.
EMBO J., 37, 2018
|
|
5APO
 | | Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and C-terminally tagged Rei1 | | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, N. | | 登録日 | 2015-09-17 | | 公開日 | 2015-12-16 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation.
Cell(Cambridge,Mass.), 164, 2016
|
|
5APN
 | | Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and N-terminally tagged Rei1 | | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, V. | | 登録日 | 2015-09-17 | | 公開日 | 2015-12-16 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | | 主引用文献 | Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation.
Cell, 164, 2015
|
|
6RS2
 | | Structure of the Bateman module of human CNNM4. | | 分子名称: | Metal transporter CNNM4 | | 著者 | Corral-Rodriguez, M.A, Stuiver, M, Gomez-Garcia, I, Oyenarte, I, Gimenez, P, Ereno-Orbea, J, Diercks, T, Muller, D, Martinez-Cruz, L.A. | | 登録日 | 2019-05-21 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.694 Å) | | 主引用文献 | Structural Insights into the Intracellular Region of the Human Magnesium Transport Mediator CNNM4.
Int J Mol Sci, 20, 2019
|
|
7QDD
 | |
7QDE
 | |
6MV5
 | |
2MJH
 | |
6E4Y
 | |
6E4Z
 | |
6VDP
 | | Crystal structure of SfmD truncated variant | | 分子名称: | 3-methyl-L-tyrosine peroxygenase, HEME C | | 著者 | Shin, I, Liu, A. | | 登録日 | 2019-12-27 | | 公開日 | 2021-03-10 | | 最終更新日 | 2021-07-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A novel catalytic heme cofactor in SfmD with a single thioether bond and a bis -His ligand set revealed by a de novo crystal structural and spectroscopic study.
Chem Sci, 12, 2021
|
|
6VDZ
 | |
6VDQ
 | | Crystal structure of SfmD | | 分子名称: | 3-methyl-L-tyrosine peroxygenase, HEME C | | 著者 | Shin, I, Liu, A. | | 登録日 | 2019-12-27 | | 公開日 | 2021-03-10 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | A novel catalytic heme cofactor in SfmD with a single thioether bond and a bis -His ligand set revealed by a de novo crystal structural and spectroscopic study.
Chem Sci, 12, 2021
|
|
6VE0
 | |
7LFA
 | | Fab 3B6 bound to ApoL1 NTD | | 分子名称: | Apolipoprotein L1, CHLORIDE ION, Fab 3B6 heavy chain, ... | | 著者 | Ultsch, M, Kirchhofer, D. | | 登録日 | 2021-01-15 | | 公開日 | 2021-08-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.857 Å) | | 主引用文献 | Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif.
Commun Biol, 4, 2021
|
|
7LFB
 | | Fab 7D6 bound to ApoL1 NTD | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Apolipoprotein L1, Fab 7D6 heavy chain, ... | | 著者 | Ultsch, M, Kirchhofer, D. | | 登録日 | 2021-01-16 | | 公開日 | 2021-08-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.913 Å) | | 主引用文献 | Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif.
Commun Biol, 4, 2021
|
|
7LF8
 | | Fab 6D12 bound to ApoL2 NTD | | 分子名称: | Apolipoprotein L2, Fab 6D12 heavy chain, Fab 6D12 light chain, ... | | 著者 | Ultsch, M, Kirchhofer, D. | | 登録日 | 2021-01-15 | | 公開日 | 2021-08-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif.
Commun Biol, 4, 2021
|
|
7LFD
 | | Fab 7D6 bound to ApoL1 BH3 like peptide | | 分子名称: | AMMONIUM ION, Apolipoprotein L1 BH3 like peptide, CITRATE ANION, ... | | 著者 | Ultsch, M, Kirchhofer, D. | | 登録日 | 2021-01-16 | | 公開日 | 2021-08-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.157 Å) | | 主引用文献 | Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif.
Commun Biol, 4, 2021
|
|
