7SJM

anti-HtrA1 Fab15H6.v4

Summary for 7SJM

• Entry DOI: 10.2210/pdb7sjm/pdb
• Descriptor: Heavy Chain, Light Chain, SULFATE ION, ... (5 entities in total)
• Functional Keywords: fab, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 47983.02

Authors

Ultsch, M.H.,Gerhardy, S. (deposition date: 2021-10-18, release date: 2022-09-07, Last modification date: 2023-10-18)

• Primary citation: Gerhardy, S.,Ultsch, M.,Tang, W.,Green, E.,Holden, J.K.,Li, W.,Estevez, A.,Arthur, C.,Tom, I.,Rohou, A.,Kirchhofer, D.; Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration.; Nat Commun, 13:5222-5222, 2022; PubMed: 36064790; DOI: 10.1038/s41467-022-32760-9

Experimental method

X-RAY DIFFRACTION (1.8 Å)