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7RRO
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BU of 7rro by Molmil
Structure of the 48-nm repeat doublet microtubule from bovine tracheal cilia
Descriptor: Armadillo repeat containing 4, Chromosome 3 C1orf194 homolog, Cilia and flagella associated protein 161, ...
Authors:Gui, M, Anderson, J.R, Botsch, J.J, Meleppattu, S, Singh, S.K, Zhang, Q, Brown, A.
Deposit date:2021-08-10
Release date:2021-10-27
Last modified:2021-11-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:De novo identification of mammalian ciliary motility proteins using cryo-EM.
Cell, 184, 2021
7SQC
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BU of 7sqc by Molmil
Ciliary C1 central pair apparatus isolated from Chlamydomonas reinhardtii
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CPC1, Calmodulin, ...
Authors:Gui, M, Wang, X, Dutcher, S.K, Brown, A, Zhang, R.
Deposit date:2021-11-05
Release date:2022-04-13
Last modified:2022-06-08
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Ciliary central apparatus structure reveals mechanisms of microtubule patterning.
Nat.Struct.Mol.Biol., 29, 2022
7SOM
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BU of 7som by Molmil
Ciliary C2 central pair apparatus isolated from Chlamydomonas reinhardtii
Descriptor: Cilia- and flagella-associated protein 20, FAP147, FAP178, ...
Authors:Gui, M, Wang, X, Dutcher, S.K, Brown, A, Zhang, R.
Deposit date:2021-11-01
Release date:2022-04-13
Last modified:2022-06-08
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Ciliary central apparatus structure reveals mechanisms of microtubule patterning.
Nat.Struct.Mol.Biol., 29, 2022
7JU4
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BU of 7ju4 by Molmil
Radial spoke 2 stalk, IDAc, and N-DRC attached with doublet microtubule
Descriptor: 28 kDa inner dynein arm light chain, axonemal, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Gui, M, Ma, M, Sze-Tu, E, Wang, X, Koh, F, Zhong, E, Berger, B, Davis, J, Dutcher, S, Zhang, R, Brown, A.
Deposit date:2020-08-19
Release date:2020-12-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of radial spokes and associated complexes important for ciliary motility.
Nat.Struct.Mol.Biol., 28, 2021
7JTK
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BU of 7jtk by Molmil
Radial spoke 1 isolated from Chlamydomonas reinhardtii
Descriptor: Cytochrome b5 heme-binding domain-containing protein, Dynein 8 kDa light chain, flagellar outer arm, ...
Authors:Gui, M, Ma, M, Sze-Tu, E, Wang, X, Koh, F, Zhong, E, Berger, B, Davis, J, Dutcher, S, Zhang, R, Brown, A.
Deposit date:2020-08-17
Release date:2020-12-16
Last modified:2021-01-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of radial spokes and associated complexes important for ciliary motility.
Nat.Struct.Mol.Biol., 28, 2021
7JTS
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BU of 7jts by Molmil
Stalk of radial spoke 1 attached with doublet microtubule from Chlamydomonas reinhardtii
Descriptor: Calmodulin, Dynein 8 kDa light chain, flagellar outer arm, ...
Authors:Gui, M, Ma, M, Sze-Tu, E, Wang, X, Koh, F, Zhong, E, Berger, B, Davis, J, Dutcher, S, Zhang, R, Brown, A.
Deposit date:2020-08-18
Release date:2020-12-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structures of radial spokes and associated complexes important for ciliary motility.
Nat.Struct.Mol.Biol., 28, 2021
5WRG
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BU of 5wrg by Molmil
SARS-CoV spike glycoprotein
Descriptor: Spike glycoprotein
Authors:Gui, M, Song, W, Xiang, Y, Wang, X.
Deposit date:2016-12-01
Release date:2017-01-11
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Cryo-electron microscopy structures of the SARS-CoV spike glycoprotein reveal a prerequisite conformational state for receptor binding.
Cell Res., 27, 2017
5XLR
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BU of 5xlr by Molmil
Structure of SARS-CoV spike glycoprotein
Descriptor: Spike glycoprotein
Authors:Gui, M, Song, W, Xiang, Y, Wang, X.
Deposit date:2017-05-11
Release date:2017-06-07
Last modified:2019-10-09
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-electron microscopy structures of the SARS-CoV spike glycoprotein reveal a prerequisite conformational state for receptor binding.
Cell Res., 27, 2017
7UN1
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BU of 7un1 by Molmil
8-nm repeat of the human sperm tip singlet microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Gui, M, Croft, J.T, Zabeo, D, Acharya, V, Kollman, J.M, Burgoyne, T, Hoog, J.L, Brown, A.
Deposit date:2022-04-08
Release date:2022-10-05
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (6 Å)
Cite:SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UNG
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BU of 7ung by Molmil
48-nm repeat of the human respiratory doublet microtubule
Descriptor: Cilia- and flagella-associated protein 161, Cilia- and flagella-associated protein 20, Cilia- and flagella-associated protein 45, ...
Authors:Gui, M, Croft, J.T, Zabeo, D, Acharya, V, Kollman, J.M, Burgoyne, T, Hoog, J.L, Brown, A.
Deposit date:2022-04-11
Release date:2022-10-05
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules.
Proc.Natl.Acad.Sci.USA, 119, 2022
8J07
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BU of 8j07 by Molmil
96nm repeat of human respiratory doublet microtubule and associated axonemal complexes
Descriptor: ACTA2, Axonemal dynein light intermediate polypeptide 1, Calaxin, ...
Authors:Gui, M, Brown, A.
Deposit date:2023-04-09
Release date:2023-07-26
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Axonemal structures reveal mechanoregulatory and disease mechanisms.
Nature, 618, 2023
6ACG
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BU of 6acg by Molmil
Trypsin-cleaved and low pH-treated SARS-CoV spike glycoprotein and ACE2 complex, ACE2-bound conformation 1
Descriptor: Angiotensin-converting enzyme 2, Spike glycoprotein
Authors:Gui, M, Song, W.
Deposit date:2018-07-26
Release date:2018-08-08
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2.
PLoS Pathog., 14, 2018
6ACJ
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BU of 6acj by Molmil
Trypsin-cleaved and low pH-treated SARS-CoV spike glycoprotein and ACE2 complex, ACE2-bound conformation 2
Descriptor: Angiotensin-converting enzyme 2, Spike glycoprotein
Authors:Gui, M, Song, W.
Deposit date:2018-07-26
Release date:2018-08-08
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2.
PLoS Pathog., 14, 2018
6ACK
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BU of 6ack by Molmil
Trypsin-cleaved and low pH-treated SARS-CoV spike glycoprotein and ACE2 complex, ACE2-bound conformation 3
Descriptor: Angiotensin-converting enzyme 2, Spike glycoprotein
Authors:Gui, M, Song, W.
Deposit date:2018-07-26
Release date:2018-08-08
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2.
PLoS Pathog., 14, 2018
6ACC
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BU of 6acc by Molmil
Trypsin-cleaved and low pH-treated SARS-CoV spike glycoprotein and ACE2 complex, ACE2-free conformation with three RBD in down conformation
Descriptor: Spike glycoprotein
Authors:Gui, M, Song, W.
Deposit date:2018-07-26
Release date:2018-08-08
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2.
PLoS Pathog., 14, 2018
6ACD
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BU of 6acd by Molmil
Trypsin-cleaved and low pH-treated SARS-CoV spike glycoprotein and ACE2 complex, ACE2-free conformation with one RBD in up conformation
Descriptor: Spike glycoprotein
Authors:Gui, M, Song, W.
Deposit date:2018-07-26
Release date:2018-08-08
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2.
PLoS Pathog., 14, 2018
7K3A
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BU of 7k3a by Molmil
Structure of full-length influenza HA with a head-binding antibody at pH 5.2, conformation B, fusion peptide release
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Gui, M, Gao, J, Xiang, Y.
Deposit date:2020-09-10
Release date:2020-11-11
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural intermediates in the low pH-induced transition of influenza hemagglutinin.
Plos Pathog., 16, 2020
7K3B
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BU of 7k3b by Molmil
Structure of full-length influenza HA with a head-binding antibody at pH 5.2, conformation C, central helices splay
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Gui, M, Gao, J, Xiang, Y.
Deposit date:2020-09-10
Release date:2020-11-11
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural intermediates in the low pH-induced transition of influenza hemagglutinin.
Plos Pathog., 16, 2020
7K37
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BU of 7k37 by Molmil
Structure of full-length influenza HA with a head-binding antibody at pH 7.8
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Gui, M, Xiang, Y, Gao, J.
Deposit date:2020-09-10
Release date:2020-11-11
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural intermediates in the low pH-induced transition of influenza hemagglutinin.
Plos Pathog., 16, 2020
7K39
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BU of 7k39 by Molmil
Structure of full-length influenza HA with a head-binding antibody at pH 5.2, conformation A, neutral pH-like
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Gui, M, Gao, J, Xiang, Y.
Deposit date:2020-09-10
Release date:2020-11-11
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural intermediates in the low pH-induced transition of influenza hemagglutinin.
Plos Pathog., 16, 2020
8SH7
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BU of 8sh7 by Molmil
TUBB4B and TUBA1A Heterodimer from Human Respiratory Doublet Microtubules
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Anderson, J.R, Gui, M, Brown, A.
Deposit date:2023-04-13
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:TUBB4B variants specifically impact ciliary function, causing a ciliopathic spectrum
To Be Published
7L0R
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BU of 7l0r by Molmil
Structure of NTS-NTSR1-Gi complex in lipid nanodisc, noncanonical state, without AHD
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G.
Deposit date:2020-12-12
Release date:2021-01-06
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.
Nat.Struct.Mol.Biol., 28, 2021
7L0P
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BU of 7l0p by Molmil
Structure of NTS-NTSR1-Gi complex in lipid nanodisc, canonical state, without AHD
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G.
Deposit date:2020-12-12
Release date:2021-01-06
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.
Nat.Struct.Mol.Biol., 28, 2021
7L0S
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BU of 7l0s by Molmil
Structure of NTS-NTSR1-Gi complex in lipid nanodisc, noncanonical state, with AHD
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G.
Deposit date:2020-12-12
Release date:2021-01-06
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.
Nat.Struct.Mol.Biol., 28, 2021
7L0Q
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BU of 7l0q by Molmil
Structure of NTS-NTSR1-Gi complex in lipid nanodisc, canonical state, with AHD
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G.
Deposit date:2020-12-12
Release date:2021-01-06
Last modified:2021-03-31
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.
Nat.Struct.Mol.Biol., 28, 2021

 

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