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8DPS
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BU of 8dps by Molmil
The structure of the interleukin 11 signalling complex, truncated gp130
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ...
Authors:Metcalfe, R.D, Hanssen, E, Griffin, M.D.W.
Deposit date:2022-07-17
Release date:2023-11-29
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant
Nat Commun, 14, 2023
8DPU
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BU of 8dpu by Molmil
The crystal structure of the IL-11 signalling complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ...
Authors:Metcalfe, R.D, Aizel, K, Griffin, M.D.W.
Deposit date:2022-07-17
Release date:2023-11-29
Method:X-RAY DIFFRACTION (3.78 Å)
Cite:Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant
Nat Commun, 14, 2023
8DPW
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BU of 8dpw by Molmil
The structure of Interleukin-11 Mutein
Descriptor: Interleukin-11, SULFATE ION
Authors:Metcalfe, R.D, Griffin, M.D.W.
Deposit date:2022-07-17
Release date:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant
Nat Commun, 14, 2023
8DPV
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BU of 8dpv by Molmil
The crystal structure of Interleukin-11, W147A mutant
Descriptor: CHLORIDE ION, Interleukin-11, SULFATE ION
Authors:Metcalfe, R.D, Griffin, M.D.W.
Deposit date:2022-07-17
Release date:2023-11-29
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant
Nat Commun, 14, 2023
1HFS
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BU of 1hfs by Molmil
CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN FIBROBLAST STROMELYSIN-1 INHIBITED WITH THE N-CARBOXY-ALKYL INHIBITOR L-764,004
Descriptor: 6-(4'-FLUORO-BIPHENYL-4-YL)-4-(3-METHYL-1-PHENYLCARBAMOYL-BUTYLCARBAMOYL)-2-[4-(1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)-BUTYL]-HEXANOIC ACID, CALCIUM ION, STROMELYSIN-1, ...
Authors:Becker, J.W.
Deposit date:1997-02-13
Release date:1998-02-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Inhibition of stromelysin-1 (MMP-3) by P1'-biphenylylethyl carboxyalkyl dipeptides.
J.Med.Chem., 40, 1997
2IJY
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BU of 2ijy by Molmil
NMR structure ensemble for the reduced DsbA disulphide oxidoreductase from Vibrio Cholerae
Descriptor: Thiol:disulfide interchange protein dsbA
Authors:Horne, J.H, Velkov, T, Scanlon, M.J.
Deposit date:2006-10-02
Release date:2007-07-17
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Probing the Flexibility of the DsbA Oxidoreductase from Vibrio cholerae-a (15)N - (1)H Heteronuclear NMR Relaxation Analysis of Oxidized and Reduced Forms of DsbA.
J.Mol.Biol., 371, 2007
2KNI
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BU of 2kni by Molmil
High-resolution solution structure of the ASIC1a blocker PcTX1
Descriptor: Psalmotoxin-1
Authors:King, G.F, Mobli, M, Saez, N.J.
Deposit date:2009-08-25
Release date:2010-09-01
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A dynamic pharmacophore drives the interaction between Psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a.
Mol.Pharmacol., 80, 2011
1BM6
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BU of 1bm6 by Molmil
SOLUTION STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN STROMELYSIN-1 COMPLEXED TO A POTENT NON-PEPTIDIC INHIBITOR, NMR, 20 STRUCTURES
Descriptor: 1-METHYLOXY-4-SULFONE-BENZENE, 3-METHYLPYRIDINE, CALCIUM ION, ...
Authors:Li, Y, Zhang, X, Melton, R, Ganu, V, Gonnella, N.C.
Deposit date:1998-07-29
Release date:1999-07-29
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of the catalytic domain of human stromelysin-1 complexed to a potent, nonpeptidic inhibitor.
Biochemistry, 37, 1998
1SLM
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BU of 1slm by Molmil
CRYSTAL STRUCTURE OF FIBROBLAST STROMELYSIN-1: THE C-TRUNCATED HUMAN PROENZYME
Descriptor: CALCIUM ION, STROMELYSIN-1, ZINC ION
Authors:Becker, J.W.
Deposit date:1995-08-03
Release date:1996-12-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Stromelysin-1: three-dimensional structure of the inhibited catalytic domain and of the C-truncated proenzyme.
Protein Sci., 4, 1995
1SLN
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BU of 1sln by Molmil
CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN FIBROBLAST STROMELYSIN-1 INHIBITED WITH THE N-CARBOXY-ALKYL INHIBITOR L-702,842
Descriptor: CALCIUM ION, N-(R-CARBOXY-ETHYL)-ALPHA-(S)-(2-PHENYLETHYL)GLYCYL-L-ARGININE-N-PHENYLAMIDE, STROMELYSIN-1, ...
Authors:Becker, J.W.
Deposit date:1995-08-03
Release date:1996-12-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Stromelysin-1: three-dimensional structure of the inhibited catalytic domain and of the C-truncated proenzyme.
Protein Sci., 4, 1995
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