1SLN

CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN FIBROBLAST STROMELYSIN-1 INHIBITED WITH THE N-CARBOXY-ALKYL INHIBITOR L-702,842

Summary for 1SLN

• Entry DOI: 10.2210/pdb1sln/pdb
• Descriptor: STROMELYSIN-1, ZINC ION, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: hydrolase, metalloprotease, fibroblast, collagen degradation
• Biological source: Homo sapiens (human)
• Cellular location: Secreted, extracellular space, extracellular matrix : P08254
• Total number of polymer chains: 1
• Total formula weight: 20151.16

Authors

Becker, J.W. (deposition date: 1995-08-03, release date: 1996-12-17, Last modification date: 2024-02-14)

• Primary citation: Becker, J.W.,Marcy, A.I.,Rokosz, L.L.,Axel, M.G.,Burbaum, J.J.,Fitzgerald, P.M.,Cameron, P.M.,Esser, C.K.,Hagmann, W.K.,Hermes, J.D.,Springer, J.P.; Stromelysin-1: three-dimensional structure of the inhibited catalytic domain and of the C-truncated proenzyme.; Protein Sci., 4:1966-1976, 1995; PubMed: 8535233

Experimental method

X-RAY DIFFRACTION (2.27 Å)