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2D26
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BU of 2d26 by Molmil
Active site distortion is sufficient for proteinase inhibit second crystal structure of covalent serpin-proteinase complex
分子名称: Alpha-1-antitrypsin, Elastase-1
著者Dementiev, A, Dobo, J, Gettins, P.G.
登録日2005-09-03
公開日2005-11-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Active Site Distortion Is Sufficient for Proteinase Inhibition by Serpins: Structure of the covalent complex of alpha 1-proteinase inhibitor with porcine pancreatic elastase
J.Biol.Chem., 281, 2006
1XQG
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3.10 A crystal structure of maspin, Space group P 4 21 2
分子名称: Maspin
著者Al-Ayyoubi, M, Gettins, P.G, Volz, K.
登録日2004-10-12
公開日2004-10-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of Human Maspin, a Serpin with Antitumor Properties: Reactive Center Loop of Mapsin is Exposed but Constrained
J.Biol.Chem., 279, 2004
1XQJ
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3.10 A Crystal structure of maspin, space group I 4 2 2
分子名称: Maspin
著者Al-Ayyoubi, M, Gettins, P.G, Volz, K.
登録日2004-10-12
公開日2004-10-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of Human Maspin, a Serpin with Antitumor Properties: Reactive Center Loop of Mapsin is Exposed but Constrained
J.Biol.Chem., 279, 2004
1OO8
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CRYSTAL STRUCTURE OF A1PI-PITTSBURGH IN THE NATIVE CONFORMATION
分子名称: Alpha-1-antitrypsin precursor
著者Dementiev, A, Simonovic, M, Volz, K, Gettins, P.G.
登録日2003-03-03
公開日2003-08-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Canonical inhibitor-like interactions explain reactivity of alpha1-proteinase inhibitor Pittsburgh and antithrombin with proteinases
J.Biol.Chem., 278, 2003
1OPH
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NON-COVALENT COMPLEX BETWEEN ALPHA-1-PI-PITTSBURGH AND S195A TRYPSIN
分子名称: Alpha-1-antitrypsin precursor, Trypsinogen, cationic precursor
著者Dementiev, A, Simonovic, M, Volz, K, Gettins, P.G.
登録日2003-03-05
公開日2003-08-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Canonical inhibitor-like interactions explain reactivity of alpha1-proteinase inhibitor Pittsburgh and antithrombin with proteinases
J.Biol.Chem., 278, 2003
1SR5
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ANTITHROMBIN-ANHYDROTHROMBIN-HEPARIN TERNARY COMPLEX STRUCTURE
分子名称: 2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-deoxy-2,3,6-tri-O-methyl-alpha-D-xylo-hexopyranose-(1-4)-2,3,6-tri-O-methyl-beta-D-glucopyranose-(1-4)-2,3-di-O-methyl-6-O-sulfo-alpha-D-glucopyranose-(1-4)-(2R,3R,4S,5S,6S)-6-(dihydroxymethyl)-3,4-dimethoxytetrahydro-2H-pyran-2,5-diol-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-(2R,3R,4S,5S,6R)-6-(dihydroxymethyl)-3,4-dimethoxytetrahydro-2H-pyran-2,5-diol-(1-4)-1,5-anhydro-3-O-methyl-2,6-di-O-sulfo-D-glucitol, ...
著者Dementiev, A, Petitou, M, Gettins, P.G.
登録日2004-03-22
公開日2004-08-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The ternary complex of antithrombin-anhydrothrombin-heparin reveals the basis of inhibitor specificity.
Nat.Struct.Mol.Biol., 11, 2004
3CVM
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High resolution structure of a stable Plasminogen activator inhibitor type-1 in its protease cleaved form
分子名称: Plasminogen activator inhibitor 1
著者Jensen, J.K, Gettins, P.G.W.
登録日2008-04-18
公開日2008-08-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献High-resolution structure of the stable plasminogen activator inhibitor type-1 variant 14-1B in its proteinase-cleaved form: a new tool for detailed interaction studies and modeling.
Protein Sci., 17, 2008
3H5C
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X-Ray Structure of Protein Z-Protein Z Inhibitor Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein Z-dependent protease inhibitor, Vitamin K-dependent protein Z, ...
著者Dementiev, A.A, Huang, X, Olson, S.T, Gettins, P.G.W.
登録日2009-04-21
公開日2010-04-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.26 Å)
主引用文献Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa.
J.Biol.Chem., 285, 2010
1IMV
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2.85 A crystal structure of PEDF
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PIGMENT EPITHELIUM-DERIVED FACTOR
著者Simonovic, M, Gettins, P.G.W, Volz, K.
登録日2001-05-11
公開日2001-09-26
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structure of human PEDF, a potent anti-angiogenic and neurite growth-promoting factor.
Proc.Natl.Acad.Sci.USA, 98, 2001
1J8E
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Crystal structure of ligand-binding repeat CR7 from LRP
分子名称: CALCIUM ION, LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1
著者Simonovic, M, Dolmer, K, Huang, W, Strickland, D.K, Volz, K, Gettins, P.G.W.
登録日2001-05-21
公開日2001-12-19
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Calcium coordination and pH dependence of the calcium affinity of ligand-binding repeat CR7 from the LRP. Comparison with related domains from the LRP and the LDL receptor.
Biochemistry, 40, 2001
1JRF
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NMR Solution Structure of the Viral Receptor Domain of Tva
分子名称: CALCIUM ION, SUBGROUP A ROUS SARCOMA VIRUS RECEPTORS PG800 AND PG950
著者Wang, Q.-Y, Huang, W, Dolmer, K, Gettins, P.G.W, Rong, L.
登録日2001-08-13
公開日2002-03-08
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of the viral receptor domain of Tva and its implications in viral entry.
J.Virol., 76, 2002
2P9R
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Human alpha2-macroglogulin is composed of multiple domains, as predicted by homology with complement component C3
分子名称: Alpha-2-macroglobulin
著者Doan, N.
登録日2007-03-26
公開日2007-08-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Human alpha2-macroglobulin is composed of multiple domains, as predicted by homology with complement component C3.
Biochem.J., 407, 2007
3Q02
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Crystal structure of plasminogen activator inhibitor-1 in a metastable active conformation.
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Plasminogen activator inhibitor 1, ...
著者Jensen, J.K, Morth, J.P.
登録日2010-12-15
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of plasminogen activator inhibitor-1 in an active conformation with normal thermodynamic stability.
J.Biol.Chem., 286, 2011
3Q03
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Crystal structure of plasminogen activator inhibitor-1 in a metastable active conformation.
分子名称: CHLORIDE ION, Plasminogen activator inhibitor 1, ZINC ION
著者Jensen, J.K, Morth, J.P.
登録日2010-12-15
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6401 Å)
主引用文献Crystal structure of plasminogen activator inhibitor-1 in an active conformation with normal thermodynamic stability.
J.Biol.Chem., 286, 2011
1BV8
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RECEPTOR DOMAIN FROM ALPHA-2-MACROGLOBULIN
分子名称: ALPHA-2-MACROGLOBULIN
著者Huang, W, Dolmer, K, Liao, X, Gettins, P.G.W.
登録日1998-09-22
公開日2000-04-05
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献NMR solution structure of complement-like repeat CR8 from the low density lipoprotein receptor-related protein.
J.Biol.Chem., 274, 1999
1CR8
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LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN COMPLEMENT REPEAT 8
分子名称: CALCIUM ION, PROTEIN (LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN)
著者Huang, W, Dolmer, K, Gettins, P.G.W.
登録日1998-12-14
公開日1998-12-23
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献NMR solution structure of complement-like repeat CR8 from the low density lipoprotein receptor-related protein.
J.Biol.Chem., 274, 1999
1D2L
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NMR SOLUTION STRUCTURE OF COMPLEMENT-LIKE REPEAT CR3 FROM THE LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN (LRP). EVIDENCE FOR SPECIFIC BINDING TO THE RECEPTOR BINDING DOMAIN OF HUMAN ALPHA-2 MACROGLOBULIN
分子名称: CALCIUM ION, LIPOPROTEIN RECEPTOR RELATED PROTEIN
著者Dolmer, K, Huang, W, Gettins, P.G.W.
登録日1999-09-24
公開日2000-01-14
最終更新日2022-12-21
実験手法SOLUTION NMR
主引用文献NMR solution structure of complement-like repeat CR3 from the low density lipoprotein receptor-related protein. Evidence for specific binding to the receptor binding domain of human alpha(2)-macroglobulin.
J.Biol.Chem., 275, 2000

219869

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