3H5C

X-Ray Structure of Protein Z-Protein Z Inhibitor Complex

Summary for 3H5C

Entry DOI	10.2210/pdb3h5c/pdb
Descriptor	Protein Z-dependent protease inhibitor, Vitamin K-dependent protein Z, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	protein z-protein z inhibitor complex, blood coagulation, cleavage on pair of basic residues, disulfide bond, egf-like domain, gamma-carboxyglutamic acid, glycoprotein, hydroxylation, secreted, serine protease homolog, protease inhibitor, serine protease inhibitor, hydrolase inhibitor-blood clotting complex, hydrolase inhibitor/blood clotting
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	85246.31
Authors	Dementiev, A.A.,Huang, X.,Olson, S.T.,Gettins, P.G.W. (deposition date: 2009-04-21, release date: 2010-04-28, Last modification date: 2020-07-29)
Primary citation	Huang, X.,Dementiev, A.,Olson, S.T.,Gettins, P.G. Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa. J.Biol.Chem., 285:20399-20409, 2010 Cited by PubMed: 20427285 DOI: 10.1074/jbc.M110.112748 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.26 Å)

Structure validation