3DIK
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8TY6
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7URT
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7URN
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5I4T
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8EET
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8EEP
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8EJL
| Structure of HIV-1 capsid declination in complex with CPSF6-FG peptide | Descriptor: | Cleavage and polyadenylation specificity factor subunit 6, HIV-1 capsid protein | Authors: | Pornillos, O, Ganser-Pornillos, B.K, Schirra, R.T, dos Santos, N.F.B. | Deposit date: | 2022-09-17 | Release date: | 2023-02-15 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | A molecular switch modulates assembly and host factor binding of the HIV-1 capsid. Nat.Struct.Mol.Biol., 30, 2023
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7LGC
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7LGA
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6BHR
| HIV-1 immature CTD-SP1 hexamer in complex with IP6 | Descriptor: | Capsid protein p24,Spacer peptide 1, INOSITOL HEXAKISPHOSPHATE | Authors: | Zadrozny, K, Wagner, J.M, Ganser-Pornillos, B.K, Pornillos, O. | Deposit date: | 2017-10-31 | Release date: | 2018-08-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.908 Å) | Cite: | Inositol phosphates are assembly co-factors for HIV-1. Nature, 560, 2018
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6BHT
| HIV-1 CA hexamer in complex with IP6, orthorhombic crystal form | Descriptor: | Capsid protein p24, INOSITOL HEXAKISPHOSPHATE | Authors: | Zadrozny, K, Wagner, J.M, Ganser-Pornillos, B.K, Pornillos, O. | Deposit date: | 2017-10-31 | Release date: | 2018-08-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.689 Å) | Cite: | Inositol phosphates are assembly co-factors for HIV-1. Nature, 560, 2018
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6BHS
| HIV-1 CA hexamer in complex with IP6, hexagonal crystal form | Descriptor: | Capsid protein p24, INOSITOL HEXAKISPHOSPHATE | Authors: | Zadrozny, K, Wagner, J.M, Ganser-Pornillos, B.K, Pornillos, O. | Deposit date: | 2017-10-31 | Release date: | 2018-08-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.984 Å) | Cite: | Inositol phosphates are assembly co-factors for HIV-1. Nature, 560, 2018
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7R7P
| Immature HIV-1 CACTD-SP1 lattice with Bevirimat (BVM) and Inositol hexakisphosphate (IP6) | Descriptor: | 3alpha-[(3-carboxy-3-methylbutanoyl)oxy]-8alpha,9beta,10alpha,13alpha,17alpha,19beta-lup-20(29)-en-28-oic acid, Gag polyprotein, INOSITOL HEXAKISPHOSPHATE | Authors: | Sarkar, S, Zadrozny, K.K, Zadorozhnyi, R, Russell, R.W, Quinn, C.M, Kleinpeter, A, Ablan, S, Meshkin, H, Perilla, J.R, Ganser-Pornillos, B.K, Pornillos, O, Freed, E.O, Gronenborn, A.M, Polenova, T. | Deposit date: | 2021-06-25 | Release date: | 2023-02-15 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Structural basis of HIV-1 maturation inhibitor binding and activity. Nat Commun, 14, 2023
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7R7Q
| Immature HIV-1 CACTD-SP1 lattice with Inositol hexakisphosphate (IP6) | Descriptor: | Gag polyprotein, INOSITOL HEXAKISPHOSPHATE | Authors: | Sarkar, S, Zadrozny, K.K, Zadorozhnyi, R, Russell, R.W, Quinn, C.M, Kleinpeter, A, Ablan, S, Meshkin, H, Perilla, J.R, Ganser-Pornillos, B.K, Pornillos, O, Freed, E.O, Gronenborn, A.M, Polenova, T. | Deposit date: | 2021-06-25 | Release date: | 2023-02-15 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Structural basis of HIV-1 maturation inhibitor binding and activity. Nat Commun, 14, 2023
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5TSV
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5TSX
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5VA4
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5TEO
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7ZUD
| Crystal structure of HIV-1 capsid IP6-CPSF6 complex | Descriptor: | Capsid protein p24, Cleavage and polyadenylation specificity factor subunit 6, INOSITOL HEXAKISPHOSPHATE | Authors: | Nicastro, G, Taylor, I.A. | Deposit date: | 2022-05-12 | Release date: | 2022-07-27 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.93 Å) | Cite: | CP-MAS and Solution NMR Studies of Allosteric Communication in CA-assemblies of HIV-1. J.Mol.Biol., 434, 2022
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5EIU
| Mini TRIM5 B-box 2 dimer C2 crystal form | Descriptor: | TRIM protein-E3 ligase Chimera, ZINC ION | Authors: | Wagner, J.M, Doss, G, Pornillos, O. | Deposit date: | 2015-10-30 | Release date: | 2016-06-15 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.908 Å) | Cite: | Mechanism of B-box 2 domain-mediated higher-order assembly of the retroviral restriction factor TRIM5 alpha. Elife, 5, 2016
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3MGE
| X-ray Structure of Hexameric HIV-1 CA | Descriptor: | 1,2-ETHANEDIOL, Capsid protein p24 | Authors: | Pornillos, O. | Deposit date: | 2010-04-05 | Release date: | 2010-07-21 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Disulfide Bond Stabilization of the Hexameric Capsomer of Human Immunodeficiency Virus. J.Mol.Biol., 401, 2010
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3P0A
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3P05
| X-ray structure of pentameric HIV-1 CA | Descriptor: | HIV-1 CA, IODIDE ION | Authors: | Pornillos, O. | Deposit date: | 2010-09-27 | Release date: | 2011-01-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Atomic-level modelling of the HIV capsid. Nature, 469, 2011
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5F7T
| TRIM5 B-box2 and coiled-coil chimera | Descriptor: | Tripartite motif-containing protein 5,Serine--tRNA ligase,Tripartite motif-containing protein 5, ZINC ION | Authors: | Wagner, J.M, Doss, G, Pornillos, O. | Deposit date: | 2015-12-08 | Release date: | 2016-06-15 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.292 Å) | Cite: | Mechanism of B-box 2 domain-mediated higher-order assembly of the retroviral restriction factor TRIM5 alpha. Elife, 5, 2016
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