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3IBA
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BU of 3iba by Molmil
Crystal structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with zoledronate, IPP and Mg2+
分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ...
著者Amzel, L.M, Huang, C.H, Gabelli, S.B, Oldfield, E.
登録日2009-07-15
公開日2010-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
Proteins, 78, 2010
3ICK
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BU of 3ick by Molmil
Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with minodronate and isopentenyl disphosphate
分子名称: (1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC ACID), 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ACETIC ACID, ...
著者Amzel, L.M, Huang, C.H, Gabelli, S.B, Oldfield, E.
登録日2009-07-17
公開日2010-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
Proteins, 78, 2010
3ICN
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BU of 3icn by Molmil
Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with isopentenyl pyrophosphate and 3-Fluoro-1-(2-hydroxy-2,2-bis-phosphono-ethyl)-pyridinium
分子名称: 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, ...
著者Amzel, L.M, Huang, C.H, Gabelli, S.B, Oldfield, E.
登録日2009-07-17
公開日2010-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
Proteins, 78, 2010
1MQE
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BU of 1mqe by Molmil
Structure of the MT-ADPRase in complex with gadolidium and ADP-ribose, a Nudix enzyme
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, ADPR pyrophosphatase, GADOLINIUM ION
著者Kang, L.-W, Gabelli, S.B, Bianchet, M.A, Cunningham, J.E, O'Handley, S.F, Amzel, L.M.
登録日2002-09-16
公開日2003-08-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and mechanism of MT-ADPRase, a Nudix hydrolase from Mycobacterium tuberculosis
Structure, 11, 2003
3ICM
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BU of 3icm by Molmil
Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with isopentenyl pyrophosphate, Mg2+ and 1-(2-Hydroxy-2,2-bis-phosphono-ethyl)-3-phenyl-pyridinium
分子名称: 1-(2-hydroxy-2,2-diphosphonoethyl)-3-phenylpyridinium, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, ...
著者Amzel, L.M, Huang, C.H, Gabelli, S.B, Oldfield, E.
登録日2009-07-17
公開日2010-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
Proteins, 78, 2010
1MK1
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BU of 1mk1 by Molmil
Structure of the MT-ADPRase in complex with ADPR, a Nudix enzyme
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, ADPR pyrophosphatase
著者Kang, L.-W, Gabelli, S.B, Bianchet, M.A, Cunningham, J.E, O'Handley, S.F, Amzel, L.M.
登録日2002-08-28
公開日2003-08-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and mechanism of MT-ADPRase, a Nudix hydrolase from Mycobacterium tuberculosis
Structure, 11, 2003
1MQW
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BU of 1mqw by Molmil
Structure of the MT-ADPRase in complex with three Mn2+ ions and AMPCPR, a Nudix enzyme
分子名称: ADPR pyrophosphatase, ALPHA-BETA METHYLENE ADP-RIBOSE, MANGANESE (II) ION
著者Kang, L.-W, Gabelli, S.B, Bianchet, M.A, Cunningham, J.E, O'Handley, S.F, Amzel, L.M.
登録日2002-09-17
公開日2003-08-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and mechanism of MT-ADPRase, a Nudix hydrolase from Mycobacterium tuberculosis
Structure, 11, 2003
1MP2
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BU of 1mp2 by Molmil
Structure of MT-ADPRase (Apoenzyme), a Nudix hydrolase from Mycobacterium tuberculosis
分子名称: ADPR pyrophosphatase
著者Kang, L.-W, Gabelli, S.B, Bianchet, M.A, Cunningham, J.E, O'Handley, S.F, Amzel, L.M.
登録日2002-09-11
公開日2003-08-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and mechanism of MT-ADPRase, a Nudix hydrolase from Mycobacterium tuberculosis
Structure, 11, 2003
6ALA
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BU of 6ala by Molmil
Crystal structure of H108A peptidylglycine alpha-hydroxylating monooxygenase (PHM) in complex with citrate
分子名称: CITRATE ANION, COPPER (II) ION, GLYCEROL, ...
著者Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M.
登録日2017-08-07
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase.
Commun Biol, 1, 2018
6ALV
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BU of 6alv by Molmil
Crystal structure of H107A-peptidylglycine alpha-hydroxylating monooxygenase (PHM) mutant (no CuH bound)
分子名称: AZIDE ION, COPPER (II) ION, GLYCEROL, ...
著者Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M.
登録日2017-08-08
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase.
Commun Biol, 1, 2018
6AN3
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BU of 6an3 by Molmil
Crystal structure of H172A-peptidylglycine alpha-hydroxylating monooxygenase (PHM) mutant soaked with peptide (no CuH bound, no peptide bound)
分子名称: COPPER (II) ION, DI(HYDROXYETHYL)ETHER, Peptidyl-glycine alpha-amidating monooxygenase
著者Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M.
登録日2017-08-11
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase.
Commun Biol, 1, 2018
6B09
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BU of 6b09 by Molmil
Crystal structure of HsNUDT16 in complex with diADPR (soaked)
分子名称: CHLORIDE ION, MAGNESIUM ION, SODIUM ION, ...
著者Thirawatananond, P, Gabelli, S.B.
登録日2017-09-14
公開日2019-01-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural analyses of NudT16-ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins.
Sci Rep, 9, 2019
6AY0
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BU of 6ay0 by Molmil
Crystal structure of H108A peptidylglycine alpha-hydroxylating monooxygenase (PHM) soaked with peptide
分子名称: COPPER (II) ION, Peptidyl-glycine alpha-amidating monooxygenase
著者Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M.
登録日2017-09-07
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase.
Commun Biol, 1, 2018
6AMP
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BU of 6amp by Molmil
Crystal structure of H172A PHM (CuH absent, CuM present)
分子名称: COPPER (II) ION, Peptidyl-glycine alpha-amidating monooxygenase
著者Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M.
登録日2017-08-10
公開日2018-07-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase.
Commun Biol, 1, 2018
6AO6
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BU of 6ao6 by Molmil
Crystal structure of H108A peptidylglycine alpha-hydroxylating monooxygenase (PHM)
分子名称: COPPER (II) ION, GLYCEROL, NICKEL (II) ION, ...
著者Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M.
登録日2017-08-15
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase.
Commun Biol, 1, 2018
5TJ7
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BU of 5tj7 by Molmil
Structure of WWP2 WW2-2,3-linker-HECT aa 334-398 linked to 485-865
分子名称: CHLORIDE ION, NEDD4-like E3 ubiquitin-protein ligase WWP2, SODIUM ION, ...
著者Chen, Z, Gabelli, S.B.
登録日2016-10-03
公開日2017-05-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A Tunable Brake for HECT Ubiquitin Ligases.
Mol. Cell, 66, 2017
5TJQ
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BU of 5tjq by Molmil
Structure of WWP2 2,3-linker-HECT
分子名称: NEDD4-like E3 ubiquitin-protein ligase WWP2,NEDD4-like E3 ubiquitin-protein ligase WWP2
著者Chen, Z, Gabelli, S.B.
登録日2016-10-04
公開日2017-05-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献A Tunable Brake for HECT Ubiquitin Ligases.
Mol. Cell, 66, 2017
5TJ8
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BU of 5tj8 by Molmil
Structure of WWP2 WW2-2,3-linker-HECT (no WW2 observed)
分子名称: NEDD4-like E3 ubiquitin-protein ligase WWP2,NEDD4-like E3 ubiquitin-protein ligase WWP2, SODIUM ION
著者Chen, Z, Gabelli, S.B.
登録日2016-10-03
公開日2017-06-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A Tunable Brake for HECT Ubiquitin Ligases.
Mol. Cell, 66, 2017
3FZD
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BU of 3fzd by Molmil
Mutation of Asn28 disrupts the enzymatic activity and dimerization of SARS 3CLpro
分子名称: 3C-like proteinase
著者Barrila, J, Gabelli, S, Bacha, U, Amzel, L.M, Freire, E.
登録日2009-01-25
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Mutation of Asn28 disrupts the dimerization and enzymatic activity of SARS 3CL(pro) .
Biochemistry, 49, 2010
4K10
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BU of 4k10 by Molmil
Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM and Mg2+
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM, ACETATE ION, ...
著者Aripirala, S, Gabelli, S, Amzel, L.M.
登録日2013-04-04
公開日2014-04-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and thermodynamic basis of the inhibition of Leishmania major farnesyl diphosphate synthase by nitrogen-containing bisphosphonates.
Acta Crystallogr.,Sect.D, 70, 2014
4JZB
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BU of 4jzb by Molmil
Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)-3-PHENYLPYRIDINIUM, IPP and Ca2+
分子名称: 1-(2-hydroxy-2,2-diphosphonoethyl)-3-phenylpyridinium, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, CALCIUM ION, ...
著者Aripirala, S, Amzel, L.M, Gabelli, S.
登録日2013-04-02
公開日2014-02-12
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and thermodynamic basis of the inhibition of Leishmania major farnesyl diphosphate synthase by nitrogen-containing bisphosphonates.
Acta Crystallogr.,Sect.D, 70, 2014
4JZX
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BU of 4jzx by Molmil
Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 3-BUTYL-1-(2,2-DIPHOSPHONOETHYL)PYRIDINIUM, IPP and Ca2+
分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, 3-butyl-1-(2,2-diphosphonoethyl)pyridinium, CALCIUM ION, ...
著者Aripirala, S, Gabelli, S, Amzel, L.M.
登録日2013-04-03
公開日2014-03-05
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and thermodynamic basis of the inhibition of Leishmania major farnesyl diphosphate synthase by nitrogen-containing bisphosphonates.
Acta Crystallogr.,Sect.D, 70, 2014
7JTX
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BU of 7jtx by Molmil
the structural basis of PTEN regulation by multi-site phosphorylation
分子名称: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
著者Park, E, Dempsey, D.R, Cole, P.
登録日2020-08-18
公開日2021-09-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.23 Å)
主引用文献The structural basis of PTEN regulation by multi-site phosphorylation.
Nat.Struct.Mol.Biol., 28, 2021
1S78
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BU of 1s78 by Molmil
Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Pertuzumab Fab heavy chain, ...
著者Franklin, M.C, Carey, K.D, Vajdos, F.F, Leahy, D.J, de Vos, A.M, Sliwkowski, M.X.
登録日2004-01-29
公開日2004-04-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex.
Cancer Cell, 5, 2004

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