7JTX
the structural basis of PTEN regulation by multi-site phosphorylation
Summary for 7JTX
Entry DOI | 10.2210/pdb7jtx/pdb |
Descriptor | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (1 entity in total) |
Functional Keywords | pten, phosphatase, cellular localization, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 42338.83 |
Authors | Park, E.,Dempsey, D.R.,Cole, P. (deposition date: 2020-08-18, release date: 2021-09-01, Last modification date: 2023-10-18) |
Primary citation | Dempsey, D.R.,Viennet, T.,Iwase, R.,Park, E.,Henriquez, S.,Chen, Z.,Jeliazkov, J.R.,Palanski, B.A.,Phan, K.L.,Coote, P.,Gray, J.J.,Eck, M.J.,Gabelli, S.B.,Arthanari, H.,Cole, P.A. The structural basis of PTEN regulation by multi-site phosphorylation. Nat.Struct.Mol.Biol., 28:858-868, 2021 Cited by PubMed: 34625746DOI: 10.1038/s41594-021-00668-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.23 Å) |
Structure validation
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