8TAH
 
 | | Cryo-EM structure of Cortactin-bound to Arp2/3 complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1A, ... | | 著者 | Fregoso, F.E, van Eeuwen, T, Dominguez, R. | | 登録日 | 2023-06-27 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Mechanism of synergistic activation of Arp2/3 complex by cortactin and WASP-family proteins.
Nat Commun, 14, 2023
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5O0U
 | | Crystal structure of tarantula venom peptide Protoxin-II | | 分子名称: | 1,2-ETHANEDIOL, Beta/omega-theraphotoxin-Tp2a, CHLORIDE ION | | 著者 | Tabor, A, McCarthy, S, Reyes, F.E. | | 登録日 | 2017-05-17 | | 公開日 | 2017-09-13 | | 最終更新日 | 2019-03-27 | | 実験手法 | X-RAY DIFFRACTION (0.99 Å) | | 主引用文献 | The Role of Disulfide Bond Replacements in Analogues of the Tarantula Toxin ProTx-II and Their Effects on Inhibition of the Voltage-Gated Sodium Ion Channel Nav1.7.
J.Am.Chem.Soc., 139, 2017
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5OJJ
 | | Crystal structure of the Zn-bound ubiquitin-conjugating enzyme Ube2T | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, Ubiquitin-conjugating enzyme E2 T, ... | | 著者 | Morreale, F.E, Testa, A, Chaugule, V.K, Bortoluzzi, A, Ciulli, A, Walden, H. | | 登録日 | 2017-07-21 | | 公開日 | 2017-10-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Mind the Metal: A Fragment Library-Derived Zinc Impurity Binds the E2 Ubiquitin-Conjugating Enzyme Ube2T and Induces Structural Rearrangements.
J. Med. Chem., 60, 2017
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4ER4
 | | HIGH-RESOLUTION X-RAY ANALYSES OF RENIN INHIBITOR-ASPARTIC PROTEINASE COMPLEXES | | 分子名称: | ENDOTHIAPEPSIN, H-142 | | 著者 | Foundling, S.I, Watson, F.E, Szelke, M, Blundell, T.L. | | 登録日 | 1991-01-05 | | 公開日 | 1991-04-15 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | High resolution X-ray analyses of renin inhibitor-aspartic proteinase complexes.
Nature, 327, 1987
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6OIF
 | | Cryo-EM structure of human TorsinA filament | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Torsin-1A | | 著者 | Zheng, W, Demircioglu, F.E, Schwartz, T.U, Egelman, E.H. | | 登録日 | 2019-04-09 | | 公開日 | 2019-07-24 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | The AAA + ATPase TorsinA polymerizes into hollow helical tubes with 8.5 subunits per turn.
Nat Commun, 10, 2019
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4FRN
 | | Crystal structure of the cobalamin riboswitch regulatory element | | 分子名称: | BARIUM ION, Cobalamin riboswitch aptamer domain, Hydroxocobalamin | | 著者 | Reyes, F.E, Johnson, J.E, Polaski, J.T, Batey, R.T. | | 登録日 | 2012-06-26 | | 公開日 | 2012-10-17 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.43 Å) | | 主引用文献 | B12 cofactors directly stabilize an mRNA regulatory switch.
Nature, 492, 2012
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4FRG
 | | Crystal structure of the cobalamin riboswitch aptamer domain | | 分子名称: | Hydroxocobalamin, IRIDIUM (III) ION, MAGNESIUM ION, ... | | 著者 | Reyes, F.E, Johnson, J.E, Polaski, J.T, Batey, R.T. | | 登録日 | 2012-06-26 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | B12 cofactors directly stabilize an mRNA regulatory switch.
Nature, 492, 2012
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4GMA
 | | Crystal structure of the adenosylcobalamin riboswitch | | 分子名称: | Adenosylcobalamin, Adenosylcobalamin riboswitch | | 著者 | Reyes, F.E, Johnson, J.E, Polaski, J.T, Batey, R.T. | | 登録日 | 2012-08-15 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.94 Å) | | 主引用文献 | B12 cofactors directly stabilize an mRNA regulatory switch.
Nature, 492, 2012
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2XO1
 | | xpt-pbuX C74U Riboswitch from B. subtilis bound to N6-methyladenine | | 分子名称: | ACETATE ION, COBALT HEXAMMINE(III), Guanine riboswitch, ... | | 著者 | Daldrop, P, Reyes, F.E, Robinson, D.A, Hammond, C.M, Lilley, D.M.J, Batey, R.T, Brenk, R. | | 登録日 | 2010-08-09 | | 公開日 | 2011-04-06 | | 最終更新日 | 2018-06-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Novel ligands for a purine riboswitch discovered by RNA-ligand docking.
Chem. Biol., 18, 2011
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3NPQ
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3NPN
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2XO0
 | | xpt-pbuX C74U Riboswitch from B. subtilis bound to 24-diamino-1,3,5- triazine identified by virtual screening | | 分子名称: | 1,3,5-TRIAZINE-2,4-DIAMINE, ACETATE ION, COBALT HEXAMMINE(III), ... | | 著者 | Daldrop, P, Reyes, F.E, Robinson, D.A, Hammond, C.M, Lilley, D.M.J, Batey, R.T, Brenk, R. | | 登録日 | 2010-08-09 | | 公開日 | 2011-04-06 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Novel ligands for a purine riboswitch discovered by RNA-ligand docking.
Chem. Biol., 18, 2011
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2XNZ
 | | xpt-pbuX C74U Riboswitch from B. subtilis bound to acetoguanamine identified by virtual screening | | 分子名称: | 6-METHYL-1,3,5-TRIAZINE-2,4-DIAMINE, ACETATE ION, COBALT HEXAMMINE(III), ... | | 著者 | Daldrop, P, Reyes, F.E, Robinson, D.A, Hammond, C.M, Lilley, D.M.J, Batey, R.T, Brenk, R. | | 登録日 | 2010-08-06 | | 公開日 | 2011-04-06 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Novel ligands for a purine riboswitch discovered by RNA-ligand docking.
Chem. Biol., 18, 2011
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2XNW
 | | XPT-PBUX C74U RIBOSWITCH FROM B. SUBTILIS BOUND TO A TRIAZOLO- TRIAZOLE-DIAMINE LIGAND IDENTIFIED BY VIRTUAL SCREENING | | 分子名称: | 3,6-diamino-1,5-dihydro[1,2,4]triazolo[4,3-b][1,2,4]triazol-4-ium, ACETATE ION, COBALT HEXAMMINE(III), ... | | 著者 | Daldrop, P, Reyes, F.E, Robinson, D.A, Hammond, C.M, Lilley, D.M.J, Brenk, R. | | 登録日 | 2010-08-06 | | 公開日 | 2011-04-06 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Novel ligands for a purine riboswitch discovered by RNA-ligand docking.
Chem. Biol., 18, 2011
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6CSF
 | | Crystal structure of sodium/alanine symporter AgcS with D-alanine bound | | 分子名称: | D-ALANINE, Monoclonal antibody FAB heavy chain, Monoclonal antibody FAB light chain, ... | | 著者 | Ma, J, Reyes, F.E, Gonen, T. | | 登録日 | 2018-03-20 | | 公開日 | 2019-01-30 | | 最終更新日 | 2019-02-20 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural basis for substrate binding and specificity of a sodium-alanine symporter AgcS.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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1A4J
 | | DIELS ALDER CATALYTIC ANTIBODY GERMLINE PRECURSOR | | 分子名称: | IMMUNOGLOBULIN, DIELS ALDER CATALYTIC ANTIBODY (HEAVY CHAIN), DIELS ALDER CATALYTIC ANTIBODY (LIGHT CHAIN) | | 著者 | Spiller, B.W, Romesburg, F.E, Schultz, P.G, Stevens, R.C. | | 登録日 | 1998-01-30 | | 公開日 | 1998-05-13 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Immunological origins of binding and catalysis in a Diels-Alderase antibody.
Science, 279, 1998
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1A4K
 | | DIELS ALDER CATALYTIC ANTIBODY WITH TRANSITION STATE ANALOGUE | | 分子名称: | ANTIBODY FAB, CADMIUM ION, [4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0 2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC ACID | | 著者 | Spiller, B.W, Romesburg, F.E, Schultz, P.G, Stevens, R.C. | | 登録日 | 1998-01-30 | | 公開日 | 1998-05-13 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Immunological origins of binding and catalysis in a Diels-Alderase antibody.
Science, 279, 1998
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1B07
 | | CRK SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR | | 分子名称: | PHENYLETHANE, PROTEIN (PROTO-ONCOGENE CRK (CRK)), PROTEIN (SH3 PEPTOID INHIBITOR) | | 著者 | Nguyen, J.T, Turck, C.W, Cohen, F.E, Zuckermann, R.N, Lim, W.A. | | 登録日 | 1998-11-17 | | 公開日 | 1999-01-06 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors.
Science, 282, 1998
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5AMU
 | | IglE I39A,Y40A,V44A | | 分子名称: | IGLE | | 著者 | Robb, C.S, Nano, F.E, Boraston, A.B. | | 登録日 | 2015-09-01 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The Structure, Dimerisation and Impact on Intramacrophage Replication of Igle in Francisella Novicida
To be Published
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5AMT
 | | Intracellular growth locus protein E | | 分子名称: | 1,2-ETHANEDIOL, BROMIDE ION, IGLE | | 著者 | Robb, C.S, Nano, F.E, Boraston, A.B. | | 登録日 | 2015-09-01 | | 公開日 | 2016-10-05 | | 最終更新日 | 2016-11-16 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Cloning, Expression, Purification, Crystallization and Preliminary X-Ray Diffraction Analysis of Intracellular Growth Locus E (Igle) Protein from Francisella Tularensis Subsp. Novicida.
Acta Crystallogr.,Sect.F, 66, 2010
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7JPN
 | | Cryo-EM structure of Arpin-bound Arp2/3 complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ... | | 著者 | van Eeuwen, T, Fregoso, F.E, Dominguez, R, Zimmet, A, Boczkowska, M, Rebowski, G. | | 登録日 | 2020-08-09 | | 公開日 | 2022-02-09 | | 最終更新日 | 2022-08-24 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | Molecular mechanism of Arp2/3 complex inhibition by Arpin.
Nat Commun, 13, 2022
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8EEY
 | | Cas7-11 in complex with DR-mismatched target RNA, Csx29 and Csx30 | | 分子名称: | Cas7-11, Csx29, Csx30, ... | | 著者 | Demircioglu, F.E, Wilkinson, M.E, Strecker, J, Li, D, Faure, G, Macrae, R.K, Zhang, F. | | 登録日 | 2022-09-07 | | 公開日 | 2022-11-16 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | | 主引用文献 | RNA-activated protein cleavage with a CRISPR-associated endopeptidase.
Science, 378, 2022
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8EEX
 | | Cas7-11 in complex with Csx29 | | 分子名称: | Cas7-11, Csx29, ZINC ION, ... | | 著者 | Demircioglu, F.E, Wilkinson, M.E, Strecker, J, Li, D, Faure, G, Macrae, R.K, Zhang, F. | | 登録日 | 2022-09-07 | | 公開日 | 2022-11-16 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | RNA-activated protein cleavage with a CRISPR-associated endopeptidase.
Science, 378, 2022
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1DO6
 | | CRYSTAL STRUCTURE OF SUPEROXIDE REDUCTASE IN THE OXIDIZED STATE AT 2.0 ANGSTROM RESOLUTION | | 分子名称: | FE (III) ION, SUPEROXIDE REDUCTASE | | 著者 | Yeh, A.P, Hu, Y, Jenney Junior, F.E, Adams, M.W, Rees, D.C. | | 登録日 | 1999-12-19 | | 公開日 | 2000-03-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of the superoxide reductase from Pyrococcus furiosus in the oxidized and reduced states.
Biochemistry, 39, 2000
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1DYZ
 | | OXIDISED AZURIN II FROM ALCALIGENES XYLOSOXIDANS | | 分子名称: | AZURIN II, COPPER (II) ION | | 著者 | Dodd, F.E, Abraham, Z.H.L, Eady, R.R, Hasnain, S.S. | | 登録日 | 2000-02-11 | | 公開日 | 2000-07-10 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structures of Oxidised and Reduced Azurin II from Alcaligenes Xylosoxidans at 1.75 Angstoms Resolution
Acta Crystallogr.,Sect.D, 56, 2000
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