1DF0
 
 | | Crystal structure of M-Calpain | | 分子名称: | CALPAIN, M-CALPAIN | | 著者 | Hosfield, C.M, Elce, J.S, Davies, P.L, Jia, Z. | | 登録日 | 1999-11-16 | | 公開日 | 2000-06-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of calpain reveals the structural basis for Ca(2+)-dependent protease activity and a novel mode of enzyme activation.
EMBO J., 18, 1999
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1NP8
 | | 18-k C-terminally trunucated small subunit of calpain | | 分子名称: | CADMIUM ION, Calcium-dependent protease, small subunit | | 著者 | Leinala, E.K, Arthur, J.S, Grochulski, P, Davies, P.L, Elce, J.S, Jia, Z. | | 登録日 | 2003-01-17 | | 公開日 | 2003-11-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A second binding site revealed by C-terminal truncation of calpain small subunit, a penta-EF-hand protein
PROTEINS: STRUCT.,FUNCT.,GENET., 53, 2003
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1KXR
 | | Crystal Structure of Calcium-Bound Protease Core of Calpain I | | 分子名称: | CALCIUM ION, thiol protease DOMAINS I AND II | | 著者 | Moldoveanu, T, Hosfield, C.M, Lim, D, Elce, J.S, Jia, Z, Davies, P.L. | | 登録日 | 2002-02-01 | | 公開日 | 2002-03-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | A Ca(2+) switch aligns the active site of calpain.
Cell(Cambridge,Mass.), 108, 2002
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1QXP
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1U5I
 | | Crystal Structure analysis of rat m-calpain mutant Lys10 Thr | | 分子名称: | Calpain 2, large [catalytic] subunit precursor, Calpain small subunit 1 | | 著者 | Hosfield, C.M, Pal, G.P, Elce, J.S, Jia, Z. | | 登録日 | 2004-07-27 | | 公開日 | 2005-01-18 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | | 主引用文献 | Activation of calpain by Ca2+: roles of the large subunit N-terminal and domain III-IV linker peptides
J.Mol.Biol., 343, 2004
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1AJ5
 | | CALPAIN DOMAIN VI APO | | 分子名称: | CALPAIN | | 著者 | Cygler, M, Grochulski, P, Blanchard, H. | | 登録日 | 1997-05-15 | | 公開日 | 1998-05-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of a calpain Ca(2+)-binding domain reveals a novel EF-hand and Ca(2+)-induced conformational changes.
Nat.Struct.Biol., 4, 1997
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1DVI
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1MDW
 | | Crystal Structure of Calcium-Bound Protease Core of Calpain II Reveals the Basis for Intrinsic Inactivation | | 分子名称: | CALCIUM ION, Calpain II, catalytic subunit | | 著者 | Moldoveanu, T, Hosfield, C.M, Lim, D, Jia, Z, Davies, P.L. | | 登録日 | 2002-08-07 | | 公開日 | 2003-04-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Calpain silencing by a reversible intrinsic mechanism.
Nat.Struct.Biol., 10, 2003
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3DF0
 | | Calcium-dependent complex between m-calpain and calpastatin | | 分子名称: | CALCIUM ION, Calpain small subunit 1, Calpain-2 catalytic subunit, ... | | 著者 | Moldoveanu, T, Gehring, K, Green, D.R. | | 登録日 | 2008-06-11 | | 公開日 | 2008-11-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains.
Nature, 456, 2008
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1TL9
 | | High resolution crystal structure of calpain I protease core in complex with leupeptin | | 分子名称: | CALCIUM ION, Calpain 1, large [catalytic] subunit, ... | | 著者 | Moldoveanu, T, Campbell, R.L, Cuerrier, D, Davies, P.L. | | 登録日 | 2004-06-09 | | 公開日 | 2004-11-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structures of Calpain-E64 and -Leupeptin Inhibitor Complexes Reveal Mobile Loops Gating the Active Site
J.Mol.Biol., 343, 2004
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1TLO
 | | High resolution crystal structure of calpain I protease core in complex with E64 | | 分子名称: | CALCIUM ION, Calpain 1, large [catalytic] subunit, ... | | 著者 | Moldoveanu, T, Campbell, R.L, Cuerrier, D, Davies, P.L. | | 登録日 | 2004-06-09 | | 公開日 | 2004-11-02 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structures of Calpain-E64 and -Leupeptin Inhibitor Complexes Reveal Mobile Loops Gating the Active Site
J.Mol.Biol., 343, 2004
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