Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1KXR

Crystal Structure of Calcium-Bound Protease Core of Calpain I

Summary for 1KXR
Entry DOI10.2210/pdb1kxr/pdb
Related1AJ5 1ALW 1DF0 1DVI 1KFU 1KFX
Descriptorthiol protease DOMAINS I AND II, CALCIUM ION (3 entities in total)
Functional Keywordspapain-related, calcium-dependent cysteine protease, two novel cooperative calcium sites, hydrolase
Biological sourceRattus norvegicus (Norway rat)
Cellular locationCytoplasm (By similarity): P97571
Total number of polymer chains2
Total formula weight77737.29
Authors
Moldoveanu, T.,Hosfield, C.M.,Lim, D.,Elce, J.S.,Jia, Z.,Davies, P.L. (deposition date: 2002-02-01, release date: 2002-03-20, Last modification date: 2023-08-16)
Primary citationMoldoveanu, T.,Hosfield, C.M.,Lim, D.,Elce, J.S.,Jia, Z.,Davies, P.L.
A Ca(2+) switch aligns the active site of calpain.
Cell(Cambridge,Mass.), 108:649-660, 2002
Cited by
PubMed: 11893336
DOI: 10.1016/S0092-8674(02)00659-1
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.07 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon