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Crystal Structure of dnaN DNA polymerase III beta subunit from Stenotrophomonas maltophilia K279a
Descriptor:	DNA polymerase III subunit beta
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-08-27
Release date:	2021-10-20
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.15 Å)
Cite:	Crystal Structure of dnaN DNA polymerase III beta subunit from Stenotrophomonas maltophilia K279a To Be Published

7RY7

Structure of Plasmepsin X (PM10, PMX) from Plasmodium falciparum 3D7
Descriptor:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasmepsin X
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-08-24
Release date:	2022-02-02
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Structures of plasmepsin X from Plasmodium falciparum reveal a novel inactivation mechanism of the zymogen and molecular basis for binding of inhibitors in mature enzyme. Protein Sci., 31, 2022

7SWH

Crystal Structure of Putative cystathionine gamma-synthase from Burkholderia pseudomallei in Complex with PLP
Descriptor:	1,2-ETHANEDIOL, Putative cystathionine gamma-synthase
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-11-19
Release date:	2021-12-01
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	Crystal Structure of Putative cystathionine gamma-synthase from Burkholderia pseudomallei in Complex with PLP to be published

7SWK

NAD/NADP-dependent betaine aldehyde dehydrogenase from Klebsiella pneumoniae subsp. pneumoniae
Descriptor:	(4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-11-20
Release date:	2021-12-01
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	NAD/NADP-dependent betaine aldehyde dehydrogenase from Klebsiella pneumoniae subsp. pneumoniae to be published

7SYB

Crystal Structure of sulfurtransferase (DsrC family protein) from Acinetobacter baumannii
Descriptor:	Sulfurtransferase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-11-24
Release date:	2021-12-08
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (1.45 Å)
Cite:	Crystal Structure of sulfurtransferase (DsrC family protein) from Acinetobacter baumannii to be published

7SYC

Crystal Structure of Nucleoside triphosphate pyrophosphohydrolase from Klebsiella pneumoniae subsp. pneumoniae
Descriptor:	7,8-dihydro-8-oxoguanine-triphosphatase, MAGNESIUM ION
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-11-24
Release date:	2021-12-08
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Crystal Structure of Nucleoside triphosphate pyrophosphohydrolase from Klebsiella pneumoniae subsp. pneumoniae to be published

7T29

Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa complexed with AMP
Descriptor:	1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Adenylosuccinate lyase
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-12-03
Release date:	2021-12-15
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa complexed with AMP to be published

7SZS

Crystal Structure of Probable GTP-binding protein EngB bound to GDP from Klebsiella pneumoniae subsp. pneumoniae
Descriptor:	1,4-BUTANEDIOL, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-11-29
Release date:	2021-12-15
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	Crystal Structure of Probable GTP-binding protein EngB bound to GDP from Klebsiella pneumoniae subsp. pneumoniae to be published

7T24

Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa
Descriptor:	Adenylosuccinate lyase, IMIDAZOLE, ISOPROPYL ALCOHOL
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-12-03
Release date:	2021-12-15
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (1.45 Å)
Cite:	Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa to be published

7TA9

Crystal Structure of thymidylate synthase from Acinetobacter baumannii
Descriptor:	1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-12-20
Release date:	2022-01-26
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	Crystal Structure of thymidylate synthase from Acinetobacter baumannii to be published

7SZV

Crystal Structure of Acyl-CoA dehydrogenase from Mycobacterium marinum in complex with FDA
Descriptor:	Acyl-CoA dehydrogenase, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-11-29
Release date:	2021-12-22
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Crystal Structure of Acyl-CoA dehydrogenase from Mycobacterium marinum in complex with FDA to be published

7STZ

Crystal Structure of Human E-cadherin EC1-5 bound by mouse monoclonal antibody Fab mAb-1_19A11
Descriptor:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-11-15
Release date:	2022-01-26
Last modified:	2023-10-25
Method:	X-RAY DIFFRACTION (2.95 Å)
Cite:	Regulation of multiple dimeric states of E-cadherin by adhesion activating antibodies revealed through Cryo-EM and X-ray crystallography. Pnas Nexus, 1, 2022

7T93

Crystal Structure of Fumarate hydratase class II from Mycobacterium ulcerans in complex with L-Malate
Descriptor:	(2S)-2-hydroxybutanedioic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, Fumarate hydratase class II
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-12-17
Release date:	2022-04-13
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.65 Å)
Cite:	Crystal Structure of Fumarate hydratase class II from Mycobacterium ulcerans in complex with L-Malate to be published

3IKF

Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with FOL fragment 717, imidazo[2,,1-b][1,3]thiazol-6-ylmethanol
Descriptor:	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ACETATE ION, CHLORIDE ION, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2009-08-05
Release date:	2009-08-18
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2.07 Å)
Cite:	Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12, 2011

4NI7

Crystal structure of human interleukin 6 in complex with a modified nucleotide aptamer (SOMAMER SL1025)
Descriptor:	Interleukin-6, SODIUM ION, SOMAmer SL1025
Authors:	Davies, D, Edwards, T, Gelinas, A, Jarvis, T, Clifton, M.C.
Deposit date:	2013-11-05
Release date:	2014-01-22
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Crystal structure of interleukin-6 in complex with a modified nucleic Acid ligand. J.Biol.Chem., 289, 2014

4NI9

Crystal structure of human interleukin 6 in complex with a modified nucleotide aptamer (SOMAMER SL1025), FORM 2
Descriptor:	Interleukin-6, SODIUM ION, SOMAmer SL1025
Authors:	Davies, D, Edwards, T, Gelinas, A, Jarvis, T, Clifton, M.C.
Deposit date:	2013-11-05
Release date:	2014-01-22
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.55 Å)
Cite:	Crystal structure of interleukin-6 in complex with a modified nucleic Acid ligand. J.Biol.Chem., 289, 2014

5JAY

Crystal Structure of an 8-amino-7-oxononanoate Synthase from Burkholderia xenovorans
Descriptor:	8-amino-7-oxononanoate synthase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2016-04-12
Release date:	2016-04-20
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	Crystal Structure of an 8-amino-7-oxononanoate Synthase from Burkholderia xenovorans to be published

5JLA

Crystal Structure of Ribose-5-phosphate Isomerase from Brucella melitensis 16M
Descriptor:	NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative short-chain dehydrogenase/reductase
Authors:	Seattle Structural Genomics Center for Infectious Disease, SSGCID, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2016-04-26
Release date:	2016-05-11
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.45 Å)
Cite:	Crystal Structure of putative short-chain dehdrogenase/reductase from Burkholderia xenovorans LB400 bound to NAD to be published

5JI5

Crystal Structure of a Histone Deacetylase superfamily protein from Burkholderia phymatumphymatum
Descriptor:	1,2-ETHANEDIOL, BuphA.10154.a.B1, SODIUM ION, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2016-04-21
Release date:	2016-05-04
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Crystal Structure of a Histone Deacetylase superfamily protein from Burkholderia phymatumphymatum to be published

5K0T

Crystal structure of methionyl-tRNA synthetase MetRS from Brucella melitensis in complex with inhibitor Chem 1415
Descriptor:	1,2-ETHANEDIOL, 1-{3-[(3-chloro-5-methoxybenzyl)amino]propyl}-3-phenylurea, Methionine--tRNA ligase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2016-05-17
Release date:	2016-05-25
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis. Plos One, 11, 2016

5K0S

Crystal structure of methionyl-tRNA synthetase MetRS from Brucella melitensis in complex with inhibitor Chem 1312
Descriptor:	2-({3-[(3,5-dichlorobenzyl)amino]propyl}amino)quinolin-4(1H)-one, Methionine--tRNA ligase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2016-05-17
Release date:	2016-05-25
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.45 Å)
Cite:	Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis. Plos One, 11, 2016

5KAK

Crystal structure of an uncharacterized NIPSNAP-like domain protein from Burkholderia xenovorans
Descriptor:	1,2-ETHANEDIOL, Uncharacterized protein
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2016-06-01
Release date:	2016-06-15
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.65 Å)
Cite:	Crystal Structure of Putative uncharacterized protein from Burkholderia xenovorans LB400 To Be Published

5JYD

Crystal Structure of a Putative Short Chain Dehydrogenase from Burkholderia cenocepacia
Descriptor:	1,2-ETHANEDIOL, IODIDE ION, MAGNESIUM ION, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2016-05-13
Release date:	2016-06-08
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (1.65 Å)
Cite:	TBD to be published

5KEU

Crystal Structure of a Taurine Dioxygenase from Burkholderia xenovorans
Descriptor:	1,2-ETHANEDIOL, FORMIC ACID, MAGNESIUM ION, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2016-06-10
Release date:	2016-06-22
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Crystal Structure of a Taurine Dioxygenase from Burkholderia xenovorans to be published

5K9F

Crystal structure of a NIPSNAP domain protein from Burkholderia xenovorans
Descriptor:	ACETATE ION, NIPSNAP domain protein, OXAMIC ACID
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2016-05-31
Release date:	2016-06-15
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.65 Å)
Cite:	Crystal structure of a NIPSNAP domain protein from Burkholderia xenovorans to be published

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