7ZG0
 
 | | Murine IL-27 in complex with IL-27Ra and a non-competing Nb | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ... | | Authors: | Skladanowska, K, Bloch, Y, Savvides, S.N. | | Deposit date: | 2022-04-01 | | Release date: | 2022-11-02 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3.18 Å) | | Cite: | Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27.
Cell Rep, 41, 2022
|
|
5FRH
 | | Solution structure of oxidised RsrA | | Descriptor: | ANTI-SIGMA FACTOR RSRA | | Authors: | Zdanowski, K, Pecqueur, L, Werner, J, Potts, J.R, Kleanthous, C. | | Deposit date: | 2015-12-17 | | Release date: | 2016-08-03 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | The Anti-Sigma Factor Rsra Responds to Oxidative Stress by Reburying its Hydrophobic Core.
Nat.Commun., 7, 2016
|
|
5FRF
 | | Solution structure of reduced and zinc-bound RsrA | | Descriptor: | ANTI-SIGMA FACTOR RSRA, ZINC ION | | Authors: | Zdanowski, K, Pecqueur, L, Werner, J, Potts, J.R, Kleanthous, C. | | Deposit date: | 2015-12-17 | | Release date: | 2016-08-03 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The Anti-Sigma Factor Rsra Responds to Oxidative Stress by Reburying its Hydrophobic Core.
Nat.Commun., 7, 2016
|
|
7ZXK
 | | Human IL-27 in complex with neutralizing SRF388 FAb fragment | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 subunit alpha, Interleukin-27 subunit beta, ... | | Authors: | Bloch, Y, Skladanowska, K, Strand, J, Welin, M, Logan, D, Hill, J, Savvides, S.N. | | Deposit date: | 2022-05-21 | | Release date: | 2022-11-02 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27.
Cell Rep, 41, 2022
|
|
1YWH
 | | crystal structure of urokinase plasminogen activator receptor | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Llinas, P, Le Du, M.H, Gardsvoll, H, Dano, K, Ploug, M, Gilquin, B, Stura, E.A, Menez, A. | | Deposit date: | 2005-02-18 | | Release date: | 2005-05-10 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide
EMBO J., 24, 2005
|
|
8C7E
 | |
2LUX
 | |
2LHL
 | | Chemical Shift Assignments and solution structure of human apo-S100A1 E32Q mutant | | Descriptor: | Protein S100-A1 | | Authors: | Ruszczynska-Bartnik, K, Zdanowski, K, Zhukov, I, Bierzynski, A, Ejchart, A. | | Deposit date: | 2011-08-12 | | Release date: | 2012-08-01 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | 1H, 13C and 15N NMR sequence-specific resonance assignments and relaxation parameters for human apo-S100A1 E32Q mutant
To be Published
|
|
2LP2
 | | Solution structure and dynamics of human S100A1 protein modified at cysteine 85 with homocysteine disulfide bond formation in calcium saturated form | | Descriptor: | 2-AMINO-4-MERCAPTO-BUTYRIC ACID, CALCIUM ION, Protein S100-A1 | | Authors: | Nowakowski, M.E, Jaremko, L, Jaremko, M, Zdanowski, K, Ejchart, A. | | Deposit date: | 2012-01-31 | | Release date: | 2013-02-20 | | Last modified: | 2024-10-09 | | Method: | SOLUTION NMR | | Cite: | Impact of calcium binding and thionylation of S100A1 protein on its nuclear magnetic resonance-derived structure and backbone dynamics.
Biochemistry, 52, 2013
|
|
2LLS
 | | solution structure of human apo-S100A1 C85M | | Descriptor: | Protein S100-A1 | | Authors: | Budzinska, M, Jaremko, L, Jaremko, M, Zdanowski, K, Zhukov, I, Bierzynski, A, Ejchart, A. | | Deposit date: | 2011-11-17 | | Release date: | 2012-12-19 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Chemical Shift Assignments and solution structure of human apo-S100A1 C85M mutant
To be Published
|
|
2LP3
 | | Solution structure of S100A1 Ca2+ | | Descriptor: | CALCIUM ION, Protein S100-A1 | | Authors: | Budzinska, M, Ruszczynska-Bartnik, K, Belczyk-Ciesielska, A, Bierzynski, A, Ejchart, A. | | Deposit date: | 2012-01-31 | | Release date: | 2013-02-20 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Impact of calcium binding and thionylation of S100A1 protein on its nuclear magnetic resonance-derived structure and backbone dynamics.
Biochemistry, 52, 2013
|
|
5MXA
 | | Structure of unbound Interleukin-23 | | Descriptor: | Interleukin-12 subunit beta, Interleukin-23 subunit alpha, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Bloch, Y, Savvides, S.N. | | Deposit date: | 2017-01-22 | | Release date: | 2017-12-20 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.501 Å) | | Cite: | Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12R beta 1.
Immunity, 48, 2018
|
|
5MZV
 | | IL-23:IL-23R:Nb22E11 complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | Authors: | Bloch, Y, Savvides, S.N. | | Deposit date: | 2017-02-01 | | Release date: | 2018-01-03 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12R beta 1.
Immunity, 48, 2018
|
|
5N2K
 | | Structure of unbound Briakinumab FAb | | Descriptor: | 1,2-ETHANEDIOL, Briakinumab FAb heavy chain, Briakinumab FAb light chain | | Authors: | Bloch, Y, Savvides, S.N. | | Deposit date: | 2017-02-07 | | Release date: | 2018-01-03 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.219 Å) | | Cite: | Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12R beta 1.
Immunity, 48, 2018
|
|
5NJD
 | | Structure of Interleukin 23 in complex with Briakinumab FAb | | Descriptor: | Briakinumab FAb Heavy chain, Briakinumab FAb Light chain, Interleukin-12 subunit beta, ... | | Authors: | Bloch, Y, Savvides, S.N. | | Deposit date: | 2017-03-28 | | Release date: | 2018-01-03 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3.9 Å) | | Cite: | Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12R beta 1.
Immunity, 48, 2018
|
|
