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3BAE
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BU of 3bae by Molmil
Crystal structure of Fab WO2 bound to the N terminal domain of Amyloid beta peptide (1-28)
Descriptor: Amyloid Beta Peptide, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa
Authors:Miles, L.A, Wun, K.S, Crespi, G.A, Parker, M.W.
Deposit date:2007-11-07
Release date:2008-04-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.593 Å)
Cite:Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope.
J.Mol.Biol., 377, 2008
3BKC
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BU of 3bkc by Molmil
Crystal structure of anti-amyloid beta FAB WO2 (P21, FormB)
Descriptor: SODIUM ION, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa
Authors:Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W.
Deposit date:2007-12-06
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope.
J.Mol.Biol., 377, 2008
3BKJ
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BU of 3bkj by Molmil
Crystal structure of Fab wo2 bound to the n terminal domain of amyloid beta peptide (1-16)
Descriptor: Amyloid Beta Peptide, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa
Authors:Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W.
Deposit date:2007-12-06
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope.
J.Mol.Biol., 377, 2008
3BKM
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BU of 3bkm by Molmil
Structure of anti-amyloid-beta Fab WO2 (Form A, P212121)
Descriptor: SODIUM ION, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa, ...
Authors:Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W.
Deposit date:2007-12-07
Release date:2008-04-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope.
J.Mol.Biol., 377, 2008
4XXD
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BU of 4xxd by Molmil
Crystal Structure of mid-region amyloid beta capture by solanezumab
Descriptor: Amyloid-beta fragment, Fab Heavy Chain, Fab Light Chain
Authors:Hermans, S.J, Crespi, G.A.N, Parker, M.W, Miles, L.A.
Deposit date:2015-01-30
Release date:2015-04-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Molecular basis for mid-region amyloid-beta capture by leading Alzheimer's disease immunotherapies.
Sci Rep, 5, 2015
4HIX
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BU of 4hix by Molmil
Crystal structure of a humanised 3D6 Fab bound to amyloid beta peptide
Descriptor: Beta-amyloid protein 40, Humanized 3D6 Fab heavy chain, Humanized 3D6 Fab light chain
Authors:Miles, L.A, Crespi, G.A.N, Parker, M.W.
Deposit date:2012-10-12
Release date:2013-03-13
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation.
Sci Rep, 3, 2013

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