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2WP8
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BU of 2wp8 by Molmil
yeast rrp44 nuclease
分子名称: CHLORIDE ION, EXOSOME COMPLEX COMPONENT RRP45, EXOSOME COMPLEX COMPONENT SKI6, ...
著者Basquin, J, Bonneau, F, Ebert, J, Lorentzen, E, Conti, E.
登録日2009-08-03
公開日2009-11-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Yeast Exosome Functions as a Macromolecular Cage to Channel RNA Substrates for Degradation.
Cell(Cambridge,Mass.), 139, 2009
2QFA
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BU of 2qfa by Molmil
Crystal structure of a Survivin-Borealin-INCENP core complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Baculoviral IAP repeat-containing protein 5, Borealin, ...
著者Jeyaprakash, A.A, Klein, U.R, Lindner, D, Ebert, J, Nigg, E.A, Conti, E.
登録日2007-06-27
公開日2007-11-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of a Survivin-Borealin-INCENP Core Complex Reveals How Chromosomal Passengers Travel Together.
Cell(Cambridge,Mass.), 131, 2007
7PW4
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BU of 7pw4 by Molmil
Human SMG1-8-9 kinase complex bound to a SMG1 inhibitor
分子名称: 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
著者Langer, L.M, Conti, E.
登録日2021-10-06
公開日2021-12-01
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Elife, 10, 2021
7PW8
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BU of 7pw8 by Molmil
Human SMG1-8-9 kinase complex bound to AMPPNP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
著者Langer, L.M, Conti, E.
登録日2021-10-06
公開日2021-12-01
実験手法ELECTRON MICROSCOPY (2.82 Å)
主引用文献Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Elife, 10, 2021
7PW7
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BU of 7pw7 by Molmil
Human SMG1-9 kinase complex bound to a SMG1 inhibitor
分子名称: 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
著者Langer, L.M, Conti, E.
登録日2021-10-06
公開日2021-12-01
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Elife, 10, 2021
7PW6
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BU of 7pw6 by Molmil
Human SMG1-8-9 kinase complex bound to a SMG1 inhibitor - SMG1 body
分子名称: 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, INOSITOL HEXAKISPHOSPHATE, Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1
著者Langer, L.M, Conti, E.
登録日2021-10-06
公開日2021-12-01
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Elife, 10, 2021
7PW9
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BU of 7pw9 by Molmil
Human SMG1-9 kinase complex bound to AMPPNP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
著者Langer, L.M, Conti, E.
登録日2021-10-06
公開日2021-12-01
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Elife, 10, 2021
7PW5
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BU of 7pw5 by Molmil
Human SMG1-8-9 kinase complex with AlphaFold predicted SMG8 C-terminus, bound to a SMG1 inhibitor
分子名称: 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
著者Langer, L.M, Conti, E.
登録日2021-10-06
公開日2021-12-01
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Elife, 10, 2021
4ZKE
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BU of 4zke by Molmil
Crystal structure of the S. cerevisiae Ski7 GTPase-like domain, bound to GTP.
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SODIUM ION, ...
著者Kowalinski, E, Conti, E.
登録日2015-04-30
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.251 Å)
主引用文献Saccharomyces cerevisiae Ski7 Is a GTP-Binding Protein Adopting the Characteristic Conformation of Active Translational GTPases.
Structure, 23, 2015
4ZKD
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BU of 4zkd by Molmil
Crystal structure of the S. cerevisiae Ski7 GTPase-like domain, bound to GDP and inorganic phosphate.
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Kowalinski, E, Conti, E.
登録日2015-04-30
公開日2015-06-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.181 Å)
主引用文献Saccharomyces cerevisiae Ski7 Is a GTP-Binding Protein Adopting the Characteristic Conformation of Active Translational GTPases.
Structure, 23, 2015
1OF5
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BU of 1of5 by Molmil
Crystal structure of Mex67-Mtr2
分子名称: MERCURY (II) ION, MRNA EXPORT FACTOR MEX67, MRNA TRANSPORT REGULATOR MTR2
著者Fribourg, S, Conti, E.
登録日2003-04-08
公開日2003-07-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural similarity in the absence of sequence homology of the messenger RNA export factors Mtr2 and p15.
EMBO Rep., 4, 2003
1OL6
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BU of 1ol6 by Molmil
Structure of unphosphorylated D274N mutant of Aurora-A
分子名称: ADENOSINE-5'-TRIPHOSPHATE, SERINE/THREONINE KINASE 6
著者Bayliss, R, Conti, E.
登録日2003-08-06
公開日2003-10-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis of Aurora-A Activation by Tpx2 at the Mitotic Spindle.
Mol.Cell, 12, 2003
1OL7
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BU of 1ol7 by Molmil
Structure of Human Aurora-A 122-403 phosphorylated on Thr287, Thr288
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SERINE/THREONINE KINASE 6
著者Bayliss, R, Conti, E.
登録日2003-08-06
公開日2003-10-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural Basis of Aurora-A Activation by Tpx2 at the Mitotic Spindle
Mol.Cell, 12, 2003
1OL5
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BU of 1ol5 by Molmil
Structure of Aurora-A 122-403, phosphorylated on Thr287, Thr288 and bound to TPX2 1-43
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RESTRICTED EXPRESSION PROLIFERATION ASSOCIATED PROTEIN 100, ...
著者Bayliss, R, Conti, E.
登録日2003-08-06
公開日2003-10-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis of Aurora-A Activation by Tpx2 at the Mitotic Spindle
Mol.Cell, 12, 2003
1HL6
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BU of 1hl6 by Molmil
A novel mode of RBD-protein recognition in the Y14-mago complex
分子名称: CG8781 PROTEIN, MAGO NASHI PROTEIN
著者Fribourg, S, Gatfield, D, Yao, W, Izaurralde, E, Conti, E.
登録日2003-03-13
公開日2003-05-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Novel Mode of Rbd-Protein Recognition in the Y14-Mago Complex
Nat.Struct.Biol., 10, 2003
1JKG
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BU of 1jkg by Molmil
Structural basis for the recognition of a nucleoporin FG-repeat by the NTF2-like domain of TAP-p15 mRNA nuclear export factor
分子名称: TAP, p15
著者Fribourg, S, Braun, I.C, Izaurralde, E, Conti, E.
登録日2001-07-12
公開日2001-10-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor.
Mol.Cell, 8, 2001
1JN5
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BU of 1jn5 by Molmil
Structural basis for the recognition of a nucleoporin FG-repeat by the NTF2-like domain of TAP-p15 mRNA export factor
分子名称: FG-repeat, TAP, p15
著者Fribourg, S, Braun, I.C, Izaurralde, E, Conti, E.
登録日2001-07-23
公開日2001-10-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor.
Mol.Cell, 8, 2001
5C0X
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BU of 5c0x by Molmil
Structure of a 12-subunit nuclear exosome complex bound to structured RNA
分子名称: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ...
著者Makino, D.L, Conti, E.
登録日2015-06-12
公開日2015-08-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.812 Å)
主引用文献RNA degradation paths in a 12-subunit nuclear exosome complex.
Nature, 524, 2015
5C0Y
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BU of 5c0y by Molmil
Crystal structure of the Rrp6 catalytic domain bound to poly(U) RNA
分子名称: Exosome complex exonuclease RRP6, MAGNESIUM ION, poly U RNA
著者Schuch, B, Conti, E.
登録日2015-06-12
公開日2015-08-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献RNA degradation paths in a 12-subunit nuclear exosome complex.
Nature, 524, 2015
5C0W
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BU of 5c0w by Molmil
Structure of a 12-subunit nuclear exosome complex bound to single-stranded RNA substrates
分子名称: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ...
著者Makino, D.L, Conti, E.
登録日2015-06-12
公開日2015-07-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (4.6 Å)
主引用文献RNA degradation paths in a 12-subunit nuclear exosome complex.
Nature, 524, 2015
4ZRL
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BU of 4zrl by Molmil
Structure of the non canonical Poly(A) polymerase complex GLD-2 - GLD-3
分子名称: CHLORIDE ION, Defective in germ line development protein 3, Poly(A) RNA polymerase gld-2
著者Nakel, K, Bonneau, F, Eckmann, C.R, Conti, E.
登録日2015-05-12
公開日2015-07-08
最終更新日2017-09-06
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structural basis for the activation of the C. elegans noncanonical cytoplasmic poly(A)-polymerase GLD-2 by GLD-3.
Proc.Natl.Acad.Sci.USA, 112, 2015
8BFJ
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BU of 8bfj by Molmil
CNOT11-GGNBP2 complex
分子名称: 1,2-ETHANEDIOL, CCR4-NOT transcription complex subunit 11, Gametogenetin-binding protein 2
著者Basquin, J, Ozgur, S, Conti, E.
登録日2022-10-26
公開日2022-12-28
最終更新日2023-02-15
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions.
Cell Rep, 42, 2023
8BFI
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BU of 8bfi by Molmil
human CNOT1-CNOT10-CNOT11 module
分子名称: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11
著者Basquin, J, Ozgur, S, Conti, E.
登録日2022-10-26
公開日2022-12-28
最終更新日2023-02-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions.
Cell Rep, 42, 2023
8BFH
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BU of 8bfh by Molmil
CNOT11
分子名称: CCR4-NOT transcription complex subunit 11
著者Basquin, J, Ozgur, S, Conti, E.
登録日2022-10-26
公開日2022-12-28
最終更新日2023-02-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions.
Cell Rep, 42, 2023
5MC6
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BU of 5mc6 by Molmil
Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Schmidt, C, Kowalinski, E, Shanmuganathan, V, Defenouillere, Q, Braunger, K, Heuer, A, Pech, M, Namane, A, Berninghausen, O, Fromont-Racine, M, Jacquier, A, Conti, E, Becker, T, Beckmann, R.
登録日2016-11-09
公開日2017-01-18
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex.
Science, 354, 2016

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