Crystal structure of a Survivin-Borealin-INCENP core complex

Summary for 2QFA

DescriptorBaculoviral IAP repeat-containing protein 5, Borealin, Inner centromere protein, ... (6 entities in total)
Functional Keywordsthree-helical-bundle, long helix, protein complex, alternative splicing, apoptosis, cell cycle, cell division, centromere, chromosomal protein, cytoplasm, metal-binding, mitosis, nucleus, phosphorylation, polymorphism, protease inhibitor, thiol protease inhibitor, zinc, coiled coil, microtubule, cell cycle-cell cycle-cell cycle complex, cell cycle/cell cycle/cell cycle
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm O15392
Nucleus, nucleolus Q53HL2
Chromosome, centromere Q9NQS7
Total number of polymer chains3
Total molecular weight29870.69
Jeyaprakash, A.A.,Klein, U.R.,Lindner, D.,Ebert, J.,Nigg, E.A.,Conti, E. (deposition date: 2007-06-27, release date: 2007-11-06, Last modification date: 2011-07-13)
Primary citation
Jeyaprakash, A.A.,Klein, U.R.,Lindner, D.,Ebert, J.,Nigg, E.A.,Conti, E.
Structure of a Survivin-Borealin-INCENP Core Complex Reveals How Chromosomal Passengers Travel Together.
Cell(Cambridge,Mass.), 131:271-285, 2007
PubMed: 17956729 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2007.07.045
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.208501.4%8.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-07-29