2QFA
Crystal structure of a Survivin-Borealin-INCENP core complex
Summary for 2QFA
Entry DOI | 10.2210/pdb2qfa/pdb |
Descriptor | Baculoviral IAP repeat-containing protein 5, Borealin, Inner centromere protein, ... (6 entities in total) |
Functional Keywords | three-helical-bundle, long helix, protein complex, alternative splicing, apoptosis, cell cycle, cell division, centromere, chromosomal protein, cytoplasm, metal-binding, mitosis, nucleus, phosphorylation, polymorphism, protease inhibitor, thiol protease inhibitor, zinc, coiled coil, microtubule, cell cycle-cell cycle-cell cycle complex, cell cycle/cell cycle/cell cycle |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: O15392 Nucleus, nucleolus: Q53HL2 Chromosome, centromere: Q9NQS7 |
Total number of polymer chains | 3 |
Total formula weight | 29870.69 |
Authors | Jeyaprakash, A.A.,Klein, U.R.,Lindner, D.,Ebert, J.,Nigg, E.A.,Conti, E. (deposition date: 2007-06-27, release date: 2007-11-06, Last modification date: 2024-02-21) |
Primary citation | Jeyaprakash, A.A.,Klein, U.R.,Lindner, D.,Ebert, J.,Nigg, E.A.,Conti, E. Structure of a Survivin-Borealin-INCENP Core Complex Reveals How Chromosomal Passengers Travel Together. Cell(Cambridge,Mass.), 131:271-285, 2007 Cited by PubMed: 17956729DOI: 10.1016/j.cell.2007.07.045 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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