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2QFA

Crystal structure of a Survivin-Borealin-INCENP core complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Baculoviral IAP repeat-containing protein 5polymer14216414.71UniProt (O15392)
Pfam (PF00653)
Homo sapiens (human)Apoptosis inhibitor survivin, Apoptosis inhibitor 4
2B
(B)
Borealinpolymer627649.91UniProt (Q53HL2)
Pfam (PF10444)
Homo sapiens (human)Dasra-B, hDasra-B, Cell division cycle-associated protein 8, Pluripotent embryonic stem cell-related gene 3 protein
3C
(C)
Inner centromere proteinpolymer475545.41UniProt (Q9NQS7)
Pfam (PF12178)
Homo sapiens (human)
4D
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
5E
(A)
2-(N-MORPHOLINO)-ETHANESULFONIC ACIDnon-polymer195.21Chemie (MES)
6F, G, H
(A, B, C)
waterwater18.0327Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight29610.0
Non-Polymers*Number of molecules2
Total formula weight260.6
All*Total formula weight29870.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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