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7ZKP
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BU of 7zkp by Molmil
Late assembly intermediate of the proximal proton pumping module of complex I with assembly factors NDUFAF1 and CIA84
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CARDIOLIPIN, ...
Authors:Schiller, J, Laube, E, Vonck, J, Zickermann, V.
Deposit date:2022-04-13
Release date:2022-11-23
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Insights into complex I assembly: Function of NDUFAF1 and a link with cardiolipin remodeling.
Sci Adv, 8, 2022
7ZKQ
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BU of 7zkq by Molmil
Early Pp module assembly intermediate of complex I
Descriptor: CARDIOLIPIN, Complex I intermediate-associated protein 30-domain-containing protein, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Schiller, J, Laube, E, Vonck, J, Zickermann, V.
Deposit date:2022-04-13
Release date:2022-11-23
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Insights into complex I assembly: Function of NDUFAF1 and a link with cardiolipin remodeling.
Sci Adv, 8, 2022
4K5B
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BU of 4k5b by Molmil
Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W
Descriptor: Apoptosis regulator BCL-W, Bcl-2-like protein 2
Authors:Schilling, J, Schoeppe, J, Sauer, E, Plueckthun, A.
Deposit date:2013-04-14
Release date:2014-04-16
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Co-Crystallization with Conformation-Specific Designed Ankyrin Repeat Proteins Explains the Conformational Flexibility of BCL-W
J.Mol.Biol., 426, 2014
4K5A
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BU of 4k5a by Molmil
Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W
Descriptor: Bcl-2-like protein 2, Designed Ankyrin Repeat Protein 013_D12
Authors:Schilling, J, Schoeppe, J, Sauer, E, Plueckthun, A.
Deposit date:2013-04-14
Release date:2014-04-16
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Co-Crystallization with Conformation-Specific Designed Ankyrin Repeat Proteins Explains the Conformational Flexibility of BCL-W
J.Mol.Biol., 426, 2014
4K5C
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BU of 4k5c by Molmil
From DARPins to LoopDARPins: Novel LoopDARPin Design Allows the Selection of Low Picomolar Binders in a Single Round of Ribosome Display
Descriptor: Loop Designed Ankyrin Repeat Protein Nran1_G06_C
Authors:Schilling, J, Schoeppe, J, Plueckthun, A.
Deposit date:2013-04-14
Release date:2013-11-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:From DARPins to LoopDARPins: novel LoopDARPin design allows the selection of low picomolar binders in a single round of ribosome display
J.Mol.Biol., 426, 2014
1U6U
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BU of 1u6u by Molmil
NMR structure of a V3 (IIIB isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody
Descriptor: V3 peptide
Authors:Rosen, O, Chill, J, Sharon, M, Kessler, N, Mester, B, Zolla-Pazner, S, Anglister, J.
Deposit date:2004-08-02
Release date:2005-04-05
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Induced fit in HIV-neutralizing antibody complexes: evidence for alternative conformations of the gp120 V3 loop and the molecular basis for broad neutralization.
Biochemistry, 44, 2005
1U6V
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BU of 1u6v by Molmil
NMR structure of a V3 (IIIB isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody
Descriptor: V3 peptide
Authors:Rosen, O, Chill, J, Sharon, M, Kessler, N, Mester, B, Zolla-Pazner, S, Anglister, J.
Deposit date:2004-08-02
Release date:2005-04-05
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Induced fit in HIV-neutralizing antibody complexes: evidence for alternative conformations of the gp120 V3 loop and the molecular basis for broad neutralization.
Biochemistry, 44, 2005
4HRN
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BU of 4hrn by Molmil
Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2
Descriptor: Designed Ankyrin Repeat Protein H10-2-G, Receptor tyrosine-protein kinase erbB-2
Authors:Jost, C, Schilling, J, Plueckthun, A.
Deposit date:2012-10-28
Release date:2013-10-16
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2.
Structure, 21, 2013
4HRL
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BU of 4hrl by Molmil
Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2
Descriptor: Designed Ankyrin Repeat Protein 9_29, Receptor tyrosine-protein kinase erbB-2
Authors:Jost, C, Schilling, J, Plueckthun, A.
Deposit date:2012-10-28
Release date:2013-10-16
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2.
Structure, 21, 2013
4HRM
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BU of 4hrm by Molmil
Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2
Descriptor: Designed Ankyrin Repeat Protein 9_26, Domain I of receptor tyrosine-protein kinase erbB-2
Authors:Jost, C, Schilling, J, Plueckthun, A.
Deposit date:2012-10-28
Release date:2013-10-16
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2.
Structure, 21, 2013
1LJZ
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BU of 1ljz by Molmil
NMR structure of an AChR-peptide (Torpedo Californica, alpha-subunit residues 182-202) in complex with alpha-Bungarotoxin
Descriptor: Acetylcholine receptor protein, alpha-Bungarotoxin
Authors:Samson, A.O, Scherf, T, Eisenstein, M, Chill, J.H, Anglister, J.
Deposit date:2002-04-23
Release date:2002-07-17
Last modified:2024-11-20
Method:SOLUTION NMR
Cite:The mechanism for acetylcholine receptor inhibition by alpha-neurotoxins and species-specific resistance to alpha-bungarotoxin revealed by NMR.
Neuron, 35, 2002
1L4W
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BU of 1l4w by Molmil
NMR structure of an AChR-peptide (Torpedo Californica, alpha-subunit residues 182-202) in complex with alpha-Bungarotoxin
Descriptor: Acetylcholine receptor protein, alpha-Bungarotoxin
Authors:Samson, A.O, Scherf, T, Rodriguez, E, Eisenstein, M, Anglister, J.
Deposit date:2002-03-06
Release date:2002-07-17
Last modified:2024-11-20
Method:SOLUTION NMR
Cite:The mechanism for acetylcholine receptor inhibition by alpha-neurotoxins and species-specific resistance to alpha-bungarotoxin revealed by NMR.
Neuron, 35, 2002
6Z0Y
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BU of 6z0y by Molmil
HtrA1 inactive protease domain S328A with CARASIL mutations D174R R274Q
Descriptor: SULFATE ION, Serine protease HTRA1
Authors:Vetter, I.R, Stege, P, Ingendahl, L, Ehrmann, M.
Deposit date:2020-05-11
Release date:2021-05-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Repair strategies addressing pathogenic protein conformations
To Be Published
6Z0E
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BU of 6z0e by Molmil
HtrA1 inactive protease domain S328A with CARASIL mutation R274Q
Descriptor: CALCIUM ION, Serine protease HTRA1
Authors:Vetter, I.R, Stege, P, Ingendahl, L, Ehrmann, M.
Deposit date:2020-05-08
Release date:2021-05-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Repair strategies addressing pathogenic protein conformations
To Be Published
6Z0X
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BU of 6z0x by Molmil
HtrA1 inactive protease domain S328A with CARASIL mutations D174R R274Q
Descriptor: SULFATE ION, Serine protease HTRA1
Authors:Vetter, I.R, Stege, P, Ingendahl, L, Ehrmann, M.
Deposit date:2020-05-11
Release date:2021-05-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Repair strategies addressing pathogenic protein conformations
To Be Published
5OY6
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BU of 5oy6 by Molmil
Crystal structure of the ACVR1 (ALK2) kinase in complex with cyclical inhibitor OD36.
Descriptor: 1,2-ETHANEDIOL, Activin receptor type-1, cyclical inhibitor OD36
Authors:Williams, E.P, Pinkas, D.M, Krojer, T, Kupinska, K, Mahajan, P, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N.
Deposit date:2017-09-07
Release date:2017-09-27
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Establishment and characterization of endothelial colony forming cells as a surrogate model for Fibrodysplasia Ossificans Progressiva
To Be Published
6ZWT
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BU of 6zwt by Molmil
Crystal structure of DNA-binding domain of OmpR of two-component system of Acinetobacter baumannii
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, SULFATE ION, ...
Authors:Narwal, M, Lucchini, V, Trebosc, V, Gartenmann, S, Pieren, M, Kemmer, C, Kammerer, R.A.
Deposit date:2020-07-28
Release date:2021-08-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Targeting virulence regulation to disarm Acinetobacter baumannii pathogenesis.
Virulence, 13, 2022
1UTR
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BU of 1utr by Molmil
UTEROGLOBIN-PCB COMPLEX (REDUCED FORM)
Descriptor: 4,4'-BIS([H]METHYLSULFONYL)-2,2',5,5'-TETRACHLOROBIPHENYL, UTEROGLOBIN
Authors:Hard, T, Barnes, H.J, Larsson, C, Gustafsson, J.-A, Lund, J.
Deposit date:1995-09-01
Release date:1995-12-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of a mammalian PCB-binding protein in complex with a PCB.
Nat.Struct.Biol., 2, 1995
1CFB
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BU of 1cfb by Molmil
CRYSTAL STRUCTURE OF TANDEM TYPE III FIBRONECTIN DOMAINS FROM DROSOPHILA NEUROGLIAN AT 2.0 ANGSTROMS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DROSOPHILA NEUROGLIAN, ...
Authors:Huber, A.H, Wang, Y.E, Bieber, A.J, Bjorkman, P.J.
Deposit date:1994-08-27
Release date:1994-11-30
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of tandem type III fibronectin domains from Drosophila neuroglian at 2.0 A.
Neuron, 12, 1994

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