6Z0Y

HtrA1 inactive protease domain S328A with CARASIL mutations D174R R274Q

Summary for 6Z0Y

• Entry DOI: 10.2210/pdb6z0y/pdb
• Related: 6Z0E 6Z0X
• Descriptor: Serine protease HTRA1, SULFATE ION (3 entities in total)
• Functional Keywords: hydrolase protease htra family carasil mutations trimerization, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 77362.33

Authors

Vetter, I.R.,Stege, P.,Ingendahl, L.,Ehrmann, M. (deposition date: 2020-05-11, release date: 2021-05-19, Last modification date: 2024-01-24)

• Primary citation: Ingendahl, L.,Beaufort, N.,Kuszner, M.,Vetter, I.R.,Stege, P.,Ruiz-Blanco, Y.B.,Bravo-Rodriguez, K.,Beuck, C.,Schillinger, J.,Rey, J.,Roberti, A.,Hagemeier, B.,Hu, X.-Y.,Clausen, T.,Sanchez-Garcia, E.,Schmuck, C.,Dichgans, M.,Ehrmann, M.; Repair strategies addressing pathogenic protein conformations; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)