5HH1
 
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5HGZ
 | | Crystal structure of human Naa60 in complex with acetyl-CoA | | Descriptor: | ACETYL COENZYME *A, MALONIC ACID, N-alpha-acetyltransferase 60 | | Authors: | Chen, J.Y, Liu, L, Yun, C.H. | | Deposit date: | 2016-01-09 | | Release date: | 2016-09-14 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.383 Å) | | Cite: | Structure and function of human Naa60 (NatF), a Golgi-localized bi-functional acetyltransferase
Sci Rep, 6, 2016
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5HH0
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4YL9
 | | Crystal Structure of wild-type of hsp14.1 from Sulfolobus solfatataricus P2 | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Heat shock protein Hsp20 | | Authors: | Liu, L, Chen, J.Y, Yun, C.H. | | Deposit date: | 2015-03-05 | | Release date: | 2015-11-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.353 Å) | | Cite: | Active-State Structures of a Small Heat-Shock Protein Revealed a Molecular Switch for Chaperone Function
Structure, 23, 2015
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4YLC
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4YLB
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5ZQG
 | | Complex structure of PEDV 3CLpro mutant (C144A) with NEMO-231 peptite substrate | | Descriptor: | Non-structural protein, PEPTIDE LEU-ALA-GLN-LEU-GLN-VAL-ALA | | Authors: | Gang, Y, Chen, J.Y, Dang, W, Xiao, S.B, Peng, G.Q. | | Deposit date: | 2018-04-18 | | Release date: | 2019-05-22 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Complex structure of PEDV 3CLpro mutant (C144A) with NEMO peptite substrate
To Be Published
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6IEG
 | | Crystal structure of human MTR4 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Exosome RNA helicase MTR4, MAGNESIUM ION | | Authors: | Chen, J.Y, Yun, C.H. | | Deposit date: | 2018-09-14 | | Release date: | 2019-04-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.55 Å) | | Cite: | NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction.
Genes Dev., 33, 2019
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6IEH
 | | Crystal structures of the hMTR4-NRDE2 complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Exosome RNA helicase MTR4, ... | | Authors: | Chen, J.Y, Yun, C.H. | | Deposit date: | 2018-09-14 | | Release date: | 2019-04-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.892 Å) | | Cite: | NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction.
Genes Dev., 33, 2019
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4XSQ
 | | Structure of a variable lymphocyte receptor-like protein Bf66946 from Branchiostoma floridae | | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, variable lymphocyte receptor-like protein Bf66946 | | Authors: | Cao, D.D, Cheng, W, Jiang, Y.L, Wang, W.J, Li, Q, Chen, Y, Zhou, C.Z. | | Deposit date: | 2015-01-22 | | Release date: | 2016-03-23 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Structure of a variable lymphocyte receptor-like protein from the amphioxus Branchiostoma floridae.
Sci Rep, 6, 2016
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1QLY
 | | NMR Study of the SH3 Domain From Bruton's Tyrosine Kinase, 20 Structures | | Descriptor: | TYROSINE-PROTEIN KINASE BTK | | Authors: | Tzeng, S.R, Lou, Y.C, Pai, M.T, Chen, C, Chen, S.H, Cheng, J.Y. | | Deposit date: | 1999-09-20 | | Release date: | 1999-12-14 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the Human Btk SH3 Domain Complexed with a Proline-Rich Peptide from P120Cbl
J.Biomol.NMR, 16, 2000
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5HU9
 | | Crystal structure of ABL1 in complex with CHMFL-074 | | Descriptor: | 1,2-ETHANEDIOL, 4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[1-(pyridin-3-ylcarbonyl)piperidin-4-yl]oxy}phenyl)-3-(trifluoromethyl)benzamide, CHLORIDE ION, ... | | Authors: | Kong, L.L, Yun, C.H. | | Deposit date: | 2016-01-27 | | Release date: | 2016-07-13 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.529 Å) | | Cite: | Discovery and characterization of a novel potent type II native and mutant BCR-ABL inhibitor (CHMFL-074) for Chronic Myeloid Leukemia (CML)
Oncotarget, 7, 2016
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5ZWJ
 | | Crystal structure of EGFR 675-1022 T790M/C797S/V948R in complex with EAI045 | | Descriptor: | (2R)-2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide, Epidermal growth factor receptor | | Authors: | Zhao, P, Yun, C.H. | | Deposit date: | 2018-05-15 | | Release date: | 2018-07-25 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of EGFR T790M/C797S/V948R in complex with EAI045.
Biochem. Biophys. Res. Commun., 502, 2018
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