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7WWG
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Crystal structure of Saccharomyces cerevisiae Sfh2 complexed with phosphatidylinositol in an open conformation
分子名称: (1R)-2-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Phosphatidylinositol transfer protein CSR1
著者Chen, L, Tan, L, Im, Y.J.
登録日2022-02-12
公開日2022-07-13
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural basis of ligand recognition and transport by Sfh2, a yeast phosphatidylinositol transfer protein of the Sec14 superfamily.
Acta Crystallogr D Struct Biol, 78, 2022
7WWE
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Crystal structure of Saccharomyces cerevisiae Sfh2 in an apo form
分子名称: Phosphatidylinositol transfer protein CSR1
著者Chen, L, Tan, L, Im, Y.J.
登録日2022-02-12
公開日2022-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of ligand recognition and transport by Sfh2, a yeast phosphatidylinositol transfer protein of the Sec14 superfamily.
Acta Crystallogr D Struct Biol, 78, 2022
7WWD
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Crystal structure of Saccharomyces cerevisiae Sfh2 complexed with squalene
分子名称: (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene, Phosphatidylinositol transfer protein CSR1
著者Chen, L, Tan, L, Im, Y.J.
登録日2022-02-12
公開日2022-07-13
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structural basis of ligand recognition and transport by Sfh2, a yeast phosphatidylinositol transfer protein of the Sec14 superfamily.
Acta Crystallogr D Struct Biol, 78, 2022
7WVT
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Crystal structure of Saccharomyces cerevisiae Sfh2 complexed with phosphatidylinositol
分子名称: (1R)-2-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Phosphatidylinositol transfer protein CSR1
著者Chen, L, Tan, L, Im, Y.J.
登録日2022-02-11
公開日2022-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis of ligand recognition and transport by Sfh2, a yeast phosphatidylinositol transfer protein of the Sec14 superfamily.
Acta Crystallogr D Struct Biol, 78, 2022
7VVH
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Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation E140G
分子名称: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1,Potassium voltage-gated channel subfamily KQT member 1
著者Chen, L.
登録日2021-11-06
公開日2022-11-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.296 Å)
主引用文献Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L
To Be Published
7VVD
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Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation Q135P
分子名称: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1,Potassium voltage-gated channel subfamily KQT member 1
著者Chen, L.
登録日2021-11-05
公開日2022-11-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.134 Å)
主引用文献Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L
To Be Published
7VUO
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Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L
分子名称: CALCIUM ION, Calmodulin-1, Kv7.1
著者Chen, L.
登録日2021-11-03
公開日2022-11-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.679 Å)
主引用文献Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L
To Be Published
4U1X
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Full length GluA2-kainate-(R,R)-2b complex crystal form B
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, ...
著者Chen, L, Gouaux, E.
登録日2014-07-16
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.301 Å)
主引用文献Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U1Z
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GluA2flip sLBD complexed with kainate and (R,R)-2b crystal form D
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2,Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide
著者Chen, L, Gouaux, E.
登録日2014-07-16
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9401 Å)
主引用文献Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U21
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GluA2flip sLBD complexed with FW and (R,R)-2b crystal form E
分子名称: 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2,Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide
著者Chen, L, Gouaux, E.
登録日2014-07-16
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.3908 Å)
主引用文献Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U22
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GluA2flip sLBD complexed with FW and (R,R)-2b crystal form D
分子名称: 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide
著者Chen, L, Gouaux, E.
登録日2014-07-16
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.4409 Å)
主引用文献Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U23
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GluA2flip sLBD complexed with FW and (R,R)-2b crystal form F
分子名称: 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2,Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide
著者Chen, L, Gouaux, E.
登録日2014-07-16
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.6734 Å)
主引用文献Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U1Y
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Full length GluA2-FW-(R,R)-2b complex
分子名称: 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2, ...
著者Chen, L, Gouaux, E.
登録日2014-07-16
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.8999 Å)
主引用文献Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U1O
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GluA2flip sLBD complexed with kainate and (R,R)-2b crystal form C
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide
著者Chen, L, Gouaux, E.
登録日2014-07-15
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8501 Å)
主引用文献Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
7YSW
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Cryo-EM Structure of FGF23-FGFR4-aKlotho-HS Quaternary Complex
分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, COPPER (II) ION, Fibroblast growth factor 23, ...
著者Mohammadi, M, Chen, L.
登録日2022-08-13
公開日2023-06-14
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Structural basis for FGF hormone signalling.
Nature, 618, 2023
3BWH
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Atomic resolution structure of cucurmosin, a novel type 1 RIP from the sarcocarp of Cucurbita moschata
分子名称: 1,2-ETHANEDIOL, PHOSPHATE ION, beta-D-xylopyranose-(1-2)-[alpha-D-mannopyranose-(1-3)][alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chen, L.
登録日2008-01-09
公開日2008-10-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Atomic resolution structure of cucurmosin, a novel type 1 ribosome-inactivating protein from the sarcocarp of Cucurbita moschata.
J.Struct.Biol., 164, 2008
2HJD
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Crystal structure of a second quorum sensing antiactivator TraM2 from A. tumefaciens strain A6
分子名称: Quorum-sensing antiactivator
著者Chen, L.
登録日2006-06-30
公開日2006-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure and Mechanism of TraM2, a Second Quorum-Sensing Antiactivator of Agrobacterium tumefaciens Strain A6.
J.Bacteriol., 188, 2006
1AAN
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BU of 1aan by Molmil
CRYSTAL STRUCTURE ANALYSIS OF AMICYANIN AND APOAMICYANIN FROM PARACOCCUS DENITRIFICANS AT 2.0 ANGSTROMS AND 1.8 ANGSTROMS RESOLUTION
分子名称: AMICYANIN, COPPER (II) ION
著者Chen, L, Durley, R.C.E, Lim, L.W, Mathews, F.S.
登録日1992-04-09
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure analysis of amicyanin and apoamicyanin from Paracoccus denitrificans at 2.0 A and 1.8 A resolution.
Protein Sci., 2, 1993
6WC5
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Crystal Structure of a Ternary MEF2B/NKX2-5/myocardin enhancer DNA Complex
分子名称: Homeobox protein Nkx-2.5, Myocardin enhancer DNA, Myocyte-specific enhancer factor 2B
著者Chen, L, Lei, X.
登録日2020-03-29
公開日2020-07-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structures of Ternary Complexes of MEF2 and NKX2-5 Bound to DNA Reveal a Disease Related Protein-Protein Interaction Interface.
J.Mol.Biol., 432, 2020
3WMC
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BU of 3wmc by Molmil
Crystal structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with naphthalimide derivative Q2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-(dimethylamino)-2-(2-{[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]amino}ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione, Beta-hexosaminidase
著者Chen, L, Zhou, Y, Chen, L, Yang, Q.
登録日2013-11-16
公開日2014-11-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.095 Å)
主引用文献A crystal structure-guided rational design switching non-carbohydrate inhibitors' specificity between two beta-GlcNAcase homologs
Sci Rep, 4, 2014
3HI1
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Structure of HIV-1 gp120 (core with V3) in Complex with CD4-Binding-Site Antibody F105
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, F105 Heavy Chain, F105 Light Chain, ...
著者Kwon, Y.D, Chen, L, Zhou, T, Wu, X, O'Dell, S, Cavacini, L, Hessell, A.J, Pancera, M, Tang, M, Xu, L, Yang, Z, Zhang, M.-Y, Arthos, J, Burton, D.R, Dimitrov, D, Nabel, G.J, Posner, M, Sodroski, J, Wyatt, R, Mascola, J.R, Kwong, P.D.
登録日2009-05-18
公開日2009-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
Science, 326, 2009
6IMM
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Cryo-EM structure of an alphavirus, Sindbis virus
分子名称: Assembly protein E3, Octadecane, Spike glycoprotein E1, ...
著者Zhang, X, Ma, J, Chen, L.
登録日2018-10-23
公開日2019-03-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Implication for alphavirus host-cell entry and assembly indicated by a 3.5 angstrom resolution cryo-EM structure.
Nat Commun, 9, 2018
1RHP
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CRYSTAL STRUCTURE OF RECOMBINANT HUMAN PLATELET FACTOR 4
分子名称: PLATELET FACTOR 4
著者Chen, L, Zhang, X.
登録日1994-09-16
公開日1994-11-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of recombinant human platelet factor 4.
Biochemistry, 33, 1994
1TQE
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Mechanism of recruitment of class II histone deacetylases by myocyte enhancer factor-2
分子名称: Histone deacetylase 9, MEF2 binding site of nur77 promoter, Myocyte-specific enhancer factor 2B
著者Chen, L, Han, A, He, J, Wu, Y, Liu, J.O.
登録日2004-06-17
公開日2004-12-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Mechanism of Recruitment of Class II Histone Deacetylases by Myocyte Enhancer Factor-2.
J.Mol.Biol., 345, 2005
8X2L
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Structure of human phagocyte NADPH oxidase in the resting state in the presence of 2 mM NADPH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7D5 Fab heavy chain, 7D5 Fab light chain, ...
著者Chen, L, Liu, X.
登録日2023-11-09
公開日2024-01-24
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Structure of human phagocyte NADPH oxidase in the activated state.
Nature, 627, 2024

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