7WWG

Crystal structure of Saccharomyces cerevisiae Sfh2 complexed with phosphatidylinositol in an open conformation

Summary for 7WWG

• Entry DOI: 10.2210/pdb7wwg/pdb
• Descriptor: Phosphatidylinositol transfer protein CSR1, (1R)-2-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate (2 entities in total)
• Functional Keywords: sec14, phosphatidylinositol, squalene, transport, lipid transport
• Biological source: Saccharomyces cerevisiae S288C
• Total number of polymer chains: 1
• Total formula weight: 47435.76

Authors

Chen, L.,Tan, L.,Im, Y.J. (deposition date: 2022-02-12, release date: 2022-07-13)

• Primary citation: Chen, L.,Tan, L.,Im, Y.J.; Structural basis of ligand recognition and transport by Sfh2, a yeast phosphatidylinositol transfer protein of the Sec14 superfamily.; Acta Crystallogr D Struct Biol, 78:853-864, 2022; PubMed: 35775985; DOI: 10.1107/S2059798322005666

Experimental method

X-RAY DIFFRACTION (3.4 Å)