7WF3
 
 | | Composite map of human Kv1.3 channel in apo state with beta subunits | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3, ... | | 著者 | Tyagi, A, Ahmed, T, Jian, S, Bajaj, S, Ong, S.T, Goay, S.S.M, Zhao, Y, Vorobyov, I, Tian, C, Chandy, K.G, Bhushan, S. | | 登録日 | 2021-12-25 | | 公開日 | 2022-02-09 | | 最終更新日 | 2022-05-25 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7WF4
 | | Composite map of human Kv1.3 channel in dalazatide-bound state with beta subunits | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3, ... | | 著者 | Tyagi, A, Ahmed, T, Jian, S, Bajaj, S, Ong, S.T, Goay, S.S.M, Zhao, Y, Vorobyov, I, Tian, C, Chandy, K.G, Bhushan, S. | | 登録日 | 2021-12-25 | | 公開日 | 2022-02-09 | | 最終更新日 | 2022-05-25 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug.
Proc.Natl.Acad.Sci.USA, 119, 2022
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1BEI
 | | Shk-dnp22: A Potent Kv1.3-specific immunosuppressive polypeptide, NMR, 20 structures | | 分子名称: | POTASSIUM CHANNEL TOXIN SHK | | 著者 | Kalman, K, Pennington, M.W, Lanigan, M.D, Nguyen, A, Rauer, H, Mahnir, V, Gutman, G.A, Paschetto, K, Kem, W.R, Grissmer, S, Christian, E.P, Cahalan, M.D, Norton, R.S, Chandy, K.G. | | 登録日 | 1998-05-14 | | 公開日 | 1998-12-02 | | 最終更新日 | 2022-12-21 | | 実験手法 | SOLUTION NMR | | 主引用文献 | ShK-Dap22, a potent Kv1.3-specific immunosuppressive polypeptide.
J.Biol.Chem., 273, 1998
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1C2U
 | | SOLUTION STRUCTURE OF [ABU3,35]SHK12-28,17-32 | | 分子名称: | SYNTHETIC PEPTIDE ANALOGUE OF SHK TOXIN | | 著者 | Pennington, M.W, Lanigan, M.D, Kalman, K, Manhir, V.M, Rauer, H, McVaugh, C.T, Behm, D, Donaldson, D, Chandy, K.G, Kem, W.R, Norton, R.S. | | 登録日 | 1999-07-27 | | 公開日 | 1999-11-10 | | 最終更新日 | 2021-11-03 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Role of disulfide bonds in the structure and potassium channel blocking activity of ShK toxin.
Biochemistry, 38, 1999
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7C31
 | | Crystal structure of the grapevine defensin VvK1 | | 分子名称: | Knot1 domain-containing protein | | 著者 | Chen, M.W, Chang, S.C, Chandy, K.G, Luo, D. | | 登録日 | 2020-05-10 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Modulation of Lymphocyte Potassium Channel KV1.3 by Membrane-Penetrating, Joint-Targeting Immunomodulatory Plant Defensin.
Acs Pharmacol Transl Sci, 3, 2020
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2MD0
 | | Solution structure of ShK-like immunomodulatory peptide from Ancylostoma caninum (hookworm) | | 分子名称: | AcK1 | | 著者 | Chhabra, S, Swarbrick, J.D, Mohanty, B, Chang, S.C, Chandy, G.K, Pennington, M.W, Norton, R.S. | | 登録日 | 2013-08-28 | | 公開日 | 2014-07-02 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases.
Faseb J., 28, 2014
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7C2P
 | | Structure of Egk Peptide | | 分子名称: | Plant defensing Egk | | 著者 | El Sahili, A. | | 登録日 | 2020-05-08 | | 公開日 | 2020-09-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Modulation of Lymphocyte Potassium Channel KV1.3 by Membrane-Penetrating, Joint-Targeting Immunomodulatory Plant Defensin.
Acs Pharmacol Transl Sci, 3, 2020
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7EJ1
 | | human voltage-gated potassium channel KV1.3 | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Potassium voltage-gated channel subfamily A member 3, Voltage-gated potassium channel subunit beta-2 | | 著者 | Liu, S, Zhao, Y, Tian, C. | | 登録日 | 2021-04-01 | | 公開日 | 2021-06-09 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structures of wild-type and H451N mutant human lymphocyte potassium channel K V 1.3.
Cell Discov, 7, 2021
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7EJ2
 | | human voltage-gated potassium channel KV1.3 H451N mutant | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Potassium voltage-gated channel subfamily A member 3, Voltage-gated potassium channel subunit beta-2 | | 著者 | Liu, S, Zhao, Y, Tian, C. | | 登録日 | 2021-04-01 | | 公開日 | 2021-06-09 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structures of wild-type and H451N mutant human lymphocyte potassium channel K V 1.3.
Cell Discov, 7, 2021
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2MCR
 | | Solution structure of ShK-like immunomodulatory peptide from Brugia malayi (filarial worm) | | 分子名称: | Probable zinc metalloproteinase, putative | | 著者 | Chhabra, S, Swarbrick, J.D, Pennington, M.W, Chang, S.C, Norton, R.S. | | 登録日 | 2013-08-22 | | 公開日 | 2014-07-02 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases.
Faseb J., 28, 2014
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2K9E
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2K72
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