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5ODZ
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BU of 5odz by Molmil
CRYSTAL STRUCTURE OF THE BETA-LACTAMASE OXA-163
Descriptor: Beta-lactamase, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Lund, B.A, Carlsen, T.J.O, Leiros, H.K.S.
Deposit date:2017-07-07
Release date:2017-10-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structure, activity and thermostability investigations of OXA-163, OXA-181 and OXA-245 using biochemical analysis, crystal structures and differential scanning calorimetry analysis.
Acta Crystallogr F Struct Biol Commun, 73, 2017
5OE0
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BU of 5oe0 by Molmil
CRYSTAL STRUCTURE OF THE BETA-LACTAMASE OXA-181
Descriptor: Beta-lactamase, CHLORIDE ION, SULFATE ION
Authors:Lund, B.A, Carlsen, T.J.O, Leiros, H.K.S, Thomassen, A.M.
Deposit date:2017-07-07
Release date:2017-08-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.0500083 Å)
Cite:Structure, activity and thermostability investigations of OXA-163, OXA-181 and OXA-245 using biochemical analysis, crystal structures and differential scanning calorimetry analysis.
Acta Crystallogr F Struct Biol Commun, 73, 2017
5ACX
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BU of 5acx by Molmil
VIM-2-2, Discovery of novel inhibitor scaffolds against the metallo- beta-lactamase VIM-2 by SPR based fragment screening
Descriptor: 2-(4-fluorophenyl)carbonylbenzoic acid, BETA-LACTAMASE, CHLORIDE ION, ...
Authors:Christopeit, T, Carlsen, T.J.O, Helland, R, Leiros, H.K.S.
Deposit date:2015-08-18
Release date:2015-11-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
J.Med.Chem., 58, 2015
5ACV
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BU of 5acv by Molmil
VIM-2-OX, Discovery of novel inhibitor scaffolds against the metallo- beta-lactamase VIM-2 by SPR based fragment screening
Descriptor: BETA-LACTAMASE, CHLORIDE ION, HYDROXIDE ION, ...
Authors:Christopeit, T, Carlsen, T.J.O, Helland, R, Leiros, H.K.S.
Deposit date:2015-08-18
Release date:2015-11-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.963 Å)
Cite:Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
J.Med.Chem., 58, 2015
5ACU
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BU of 5acu by Molmil
VIM-2-NAT, Discovery of novel inhibitor scaffolds against the metallo- beta-lactamase VIM-2 by SPR based fragment screening
Descriptor: BETA-LACTAMASE, CHLORIDE ION, HYDROXIDE ION, ...
Authors:Christopeit, T, Carlsen, T.J.O, Helland, R, Leiros, H.K.S.
Deposit date:2015-08-18
Release date:2015-11-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
J.Med.Chem., 58, 2015
5ACW
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BU of 5acw by Molmil
VIM-2-1, Discovery of novel inhibitor scaffolds against the metallo- beta-lactamase VIM-2 by SPR based fragment screening
Descriptor: 4-methyl-5-(trifluoromethyl)-1,2,4-triazole-3-thiol, BETA-LACTAMASE, CHLORIDE ION, ...
Authors:Christopeit, T, Carlsen, T.J.O, Helland, R, Leiros, H.K.S.
Deposit date:2015-08-18
Release date:2015-11-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
J.Med.Chem., 58, 2015
6GOA
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BU of 6goa by Molmil
Structural basis for OXA-48 dimerization - R189A mutant
Descriptor: Beta-lactamase, CHLORIDE ION
Authors:Lund, B.A, Thomassen, A.M, Leiros, H.K.S.
Deposit date:2018-06-01
Release date:2018-07-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The biological assembly of OXA-48 reveals a dimer interface with high charge complementarity and very high affinity.
FEBS J., 285, 2018
5OE2
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BU of 5oe2 by Molmil
CRYSTAL STRUCTURE OF THE BETA-LACTAMASE OXA-245
Descriptor: Beta-lactamase, CHLORIDE ION, SODIUM ION
Authors:Lund, B.A, Leiros, H.K.S.
Deposit date:2017-07-07
Release date:2017-08-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure, activity and thermostability investigations of OXA-163, OXA-181 and OXA-245 using biochemical analysis, crystal structures and differential scanning calorimetry analysis.
Acta Crystallogr F Struct Biol Commun, 73, 2017
5OFT
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BU of 5oft by Molmil
Structural basis for OXA-48 dimerization
Descriptor: Beta-lactamase
Authors:Lund, B.A, Nesheim, B.H.B, Leiros, H.K.S.
Deposit date:2017-07-11
Release date:2018-08-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The biological assembly of OXA-48 reveals a dimer interface with high charge complementarity and very high affinity.
FEBS J., 285, 2018

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