5ACX

VIM-2-2, Discovery of novel inhibitor scaffolds against the metallo- beta-lactamase VIM-2 by SPR based fragment screening

Summary for 5ACX

Entry DOI	10.2210/pdb5acx/pdb
Related	5ACU 5ACV 5ACW
Descriptor	BETA-LACTAMASE, ZINC ION, 2-(4-fluorophenyl)carbonylbenzoic acid, ... (6 entities in total)
Functional Keywords	hydrolase
Biological source	PSEUDOMONAS AERUGINOSA
Total number of polymer chains	2
Total formula weight	57858.38
Authors	Christopeit, T.,Carlsen, T.J.O.,Helland, R.,Leiros, H.K.S. (deposition date: 2015-08-18, release date: 2015-11-04, Last modification date: 2024-01-10)
Primary citation	Christopeit, T.,Carlsen, T.J.O.,Helland, R.,Leiros, H.K.S. Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening J.Med.Chem., 58:8671-, 2015 Cited by PubMed: 26477515 DOI: 10.1021/ACS.JMEDCHEM.5B01289 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation