5ACX

VIM-2-2, Discovery of novel inhibitor scaffolds against the metallo- beta-lactamase VIM-2 by SPR based fragment screening

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	BETA-LACTAMASE	polymer	266	28400.8	2	UniProt (Q9K2N0) Pfam (PF00753)	PSEUDOMONAS AERUGINOSA
2	C, D, E, J, K... (A, B)	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
3	F, M (A, B)	2-(4-fluorophenyl)carbonylbenzoic acid	non-polymer		244.2	2	Chemie (WL3)
4	G, N (A, B)	HYDROXIDE ION	non-polymer		17.0	2	Chemie (OH)
5	H, I, O, P (A, B)	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
6	Q, R (A, B)	water	water		18.0	616	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56801.7
Non-Polymers*	Number of molecules	14
	Total formula weight	1056.7
All*	Total formula weight	57858.4

*Water molecules are not included.