5ACW
VIM-2-1, Discovery of novel inhibitor scaffolds against the metallo- beta-lactamase VIM-2 by SPR based fragment screening
Summary for 5ACW
Entry DOI | 10.2210/pdb5acw/pdb |
Related | 5ACU 5ACV 5ACX |
Descriptor | BETA-LACTAMASE, ZINC ION, 4-methyl-5-(trifluoromethyl)-1,2,4-triazole-3-thiol, ... (6 entities in total) |
Functional Keywords | hydrolase |
Biological source | PSEUDOMONAS AERUGINOSA |
Total number of polymer chains | 2 |
Total formula weight | 58102.56 |
Authors | Christopeit, T.,Carlsen, T.J.O.,Helland, R.,Leiros, H.K.S. (deposition date: 2015-08-18, release date: 2015-11-04, Last modification date: 2024-01-10) |
Primary citation | Christopeit, T.,Carlsen, T.J.O.,Helland, R.,Leiros, H.K.S. Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening J.Med.Chem., 58:8671-, 2015 Cited by PubMed: 26477515DOI: 10.1021/ACS.JMEDCHEM.5B01289 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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