5ACW

VIM-2-1, Discovery of novel inhibitor scaffolds against the metallo- beta-lactamase VIM-2 by SPR based fragment screening

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	BETA-LACTAMASE	polymer	266	28400.8	2	UniProt (Q9K2N0)	PSEUDOMONAS AERUGINOSA
2	C, D, E, K, L... (A, B)	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
3	F, G, N, O (A, B)	4-methyl-5-(trifluoromethyl)-1,2,4-triazole-3-thiol	non-polymer		183.2	4	Chemie (RHU)
4	H, I, P, Q (A, B)	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
5	J, R (A, B)	HYDROXIDE ION	non-polymer		17.0	2	Chemie (OH)
6	S, T (A, B)	water	water		18.0	674	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56801.7
Non-Polymers*	Number of molecules	16
	Total formula weight	1300.9
All*	Total formula weight	58102.6

*Water molecules are not included.