5ACU
VIM-2-NAT, Discovery of novel inhibitor scaffolds against the metallo- beta-lactamase VIM-2 by SPR based fragment screening
Summary for 5ACU
| Entry DOI | 10.2210/pdb5acu/pdb |
| Related | 5ACV 5ACW 5ACX |
| Descriptor | BETA-LACTAMASE, HYDROXIDE ION, ZINC ION, ... (5 entities in total) |
| Functional Keywords | hydrolase |
| Biological source | PSEUDOMONAS AERUGINOSA |
| Total number of polymer chains | 1 |
| Total formula weight | 28636.98 |
| Authors | Christopeit, T.,Carlsen, T.J.O.,Helland, R.,Leiros, H.K.S. (deposition date: 2015-08-18, release date: 2015-11-04, Last modification date: 2024-01-10) |
| Primary citation | Christopeit, T.,Carlsen, T.J.O.,Helland, R.,Leiros, H.K.S. Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening J.Med.Chem., 58:8671-, 2015 Cited by PubMed: 26477515DOI: 10.1021/ACS.JMEDCHEM.5B01289 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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