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6D2P
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BU of 6d2p by Molmil
Crystal structure of IOMA-class CLK31 Fab from an HIV-1 naive donor in complex with a germline-targeting gp120 engineered outer domain eOD-GT8 at 2.6 A
分子名称: GLYCEROL, Germline-targeting HIV-1 gp120 engineered outer domain eOD-GT8, IOMAclass naive CLK31 Fab heavy chain, ...
著者Sarkar, A, Wilson, I.A.
登録日2018-04-13
公開日2019-01-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen.
Sci Transl Med, 10, 2018
7CYP
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BU of 7cyp by Molmil
Complex of SARS-CoV-2 spike trimer with its neutralizing antibody HB27
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of HB27, ...
著者Wang, X, Zhu, L.
登録日2020-09-04
公開日2021-06-09
最終更新日2022-02-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Double lock of a potent human therapeutic monoclonal antibody against SARS-CoV-2.
Natl Sci Rev, 8, 2021
7U6R
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BU of 7u6r by Molmil
Cryo-EM structure of PDF-2180 Spike glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PDF-2180 Spike glycoprotein
著者Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2022-03-05
公開日2022-11-30
最終更新日2023-01-04
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Close relatives of MERS-CoV in bats use ACE2 as their functional receptors.
Nature, 612, 2022
5F59
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BU of 5f59 by Molmil
The crystal structure of MLL3 SET domain
分子名称: Histone-lysine N-methyltransferase 2C, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
著者Li, Y, Lei, M, Chen, Y.
登録日2015-12-04
公開日2016-02-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5F6L
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BU of 5f6l by Molmil
The crystal structure of MLL1 (N3861I/Q3867L) in complex with RbBP5 and Ash2L
分子名称: Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Li, Y, Lei, M, Chen, Y.
登録日2015-12-06
公開日2016-02-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5F5E
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BU of 5f5e by Molmil
The Crystal Structure of MLL1 SET domain with N3816I/Q3867L mutation
分子名称: Histone-lysine N-methyltransferase 2A, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
著者Li, Y, Lei, M, Chen, Y.
登録日2015-12-04
公開日2016-02-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5F6K
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BU of 5f6k by Molmil
Crystal structure of the MLL3-Ash2L-RbBP5 complex
分子名称: Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Li, Y, Lei, M, Chen, Y.
登録日2015-12-06
公開日2016-02-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.411 Å)
主引用文献Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
4ZRS
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BU of 4zrs by Molmil
Crystal structure of a cloned feruloyl esterase from a soil metagenomic library
分子名称: Esterase, GLYCEROL
著者Xie, W, Chen, R, Cao, L, Liu, Y.
登録日2015-05-12
公開日2016-02-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Enhancing the Thermostability of Feruloyl Esterase EstF27 by Directed Evolution and the Underlying Structural Basis
J.Agric.Food Chem., 63, 2015
7LI2
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BU of 7li2 by Molmil
Omega ester peptide pre-fuscimiditide
分子名称: Pre-fuscimiditide peptide
著者Link, A.J, Elashal, H.E.
登録日2021-01-26
公開日2022-02-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Biosynthesis and characterization of fuscimiditide, an aspartimidylated graspetide.
Nat.Chem., 14, 2022
7LIF
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BU of 7lif by Molmil
Aspartimidylated omega ester peptide fuscimiditide
分子名称: Fuscimiditide peptide
著者Link, A.J, Elashal, H.E.
登録日2021-01-27
公開日2022-02-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Biosynthesis and characterization of fuscimiditide, an aspartimidylated graspetide.
Nat.Chem., 14, 2022
8DYM
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BU of 8dym by Molmil
Aspartimidylated Graspetide Amycolimiditide
分子名称: ATP-grasp target RiPP
著者Link, A.J, Choi, B.
登録日2022-08-04
公開日2022-11-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Mechanistic Analysis of the Biosynthesis of the Aspartimidylated Graspetide Amycolimiditide.
J.Am.Chem.Soc., 144, 2022
8F53
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BU of 8f53 by Molmil
Top-down design of protein architectures with reinforcement learning
分子名称: RC_I_2
著者Borst, A.J, Baker, D.
登録日2022-11-11
公開日2023-05-10
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Top-down design of protein architectures with reinforcement learning.
Science, 380, 2023
8F54
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BU of 8f54 by Molmil
Top-down design of protein architectures with reinforcement learning
分子名称: RC_I_1
著者Borst, A.J, Baker, D.
登録日2022-11-11
公開日2023-05-10
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Top-down design of protein architectures with reinforcement learning.
Science, 380, 2023
8F4X
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BU of 8f4x by Molmil
Top-down design of protein architectures with reinforcement learning
分子名称: RC_I_1-H11
著者Borst, A.J, Baker, D.
登録日2022-11-11
公開日2023-05-10
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Top-down design of protein architectures with reinforcement learning.
Science, 380, 2023
7CWS
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BU of 7cws by Molmil
SARS-CoV-2 Spike Proteins Trimer in Complex with FC05 and H014 Fabs Cocktail
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of FC05 Fab, ...
著者Wang, L, Wang, X.
登録日2020-08-31
公開日2020-12-16
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure-based development of human antibody cocktails against SARS-CoV-2.
Cell Res., 31, 2021
5H4B
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BU of 5h4b by Molmil
Crystal structure of Cbln4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cerebellin-4
著者Zhong, C, Shen, J, Zhang, H, Ding, J.
登録日2016-10-31
公開日2017-09-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions.
Cell Rep, 20, 2017
6JCS
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BU of 6jcs by Molmil
AAV5 in complex with AAVR
分子名称: Capsid protein, Dyslexia-associated protein KIAA0319-like protein
著者Lou, Z, Zhang, R.
登録日2019-01-30
公開日2019-08-14
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
Nat Commun, 10, 2019
6JCR
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BU of 6jcr by Molmil
AAV1 in neutral condition at 3.07 Ang
分子名称: Capsid protein
著者Lou, Z, Zhang, R.
登録日2019-01-30
公開日2019-10-23
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
Nat Commun, 10, 2019
7CWU
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BU of 7cwu by Molmil
SARS-CoV-2 spike proteins trimer in complex with P17 and FC05 Fabs cocktail
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Wang, X, Wang, N.
登録日2020-08-31
公開日2020-12-16
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure-based development of human antibody cocktails against SARS-CoV-2.
Cell Res., 31, 2021
7CWT
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BU of 7cwt by Molmil
SARS-CoV-2 Spike protein in complex with hb27 and fc05 Fab cocktail
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain Fab of FC05, Heavy chain Fab of HB27, ...
著者Cui, Z, Wang, X.
登録日2020-08-31
公開日2021-06-23
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure-based development of human antibody cocktails against SARS-CoV-2.
Cell Res., 31, 2021
6JCQ
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BU of 6jcq by Molmil
AAV1 in complex with AAVR
分子名称: Capsid protein, Dyslexia-associated protein KIAA0319-like protein
著者Lou, Z, Zhang, R.
登録日2019-01-30
公開日2019-10-23
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
Nat Commun, 10, 2019
6JCT
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BU of 6jct by Molmil
AAV5 in neutral condition at 3.18 Ang
分子名称: Capsid protein
著者Lou, Z, Zhang, R.
登録日2019-01-30
公開日2019-07-31
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
Nat Commun, 10, 2019
5GSW
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BU of 5gsw by Molmil
Crystal structure of EV71 3C in complex with N69S 1.8k
分子名称: 3C protein, ~{N}-[(2~{S})-3-(4-fluorophenyl)-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepiperidin-3-yl]propan-2-yl]amino]propan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide
著者Wang, Y.
登録日2016-08-17
公開日2017-05-31
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Structure of the Enterovirus 71 3C Protease in Complex with NK-1.8k and Indications for the Development of Antienterovirus Protease Inhibitor
Antimicrob. Agents Chemother., 61, 2017
5GSO
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BU of 5gso by Molmil
Crystal Structures of EV71 3C Protease in complex with NK-1.8k
分子名称: 3C protein, ~{N}-[(2~{S})-3-(4-fluorophenyl)-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepiperidin-3-yl]propan-2-yl]amino]propan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide
著者Wang, Y.
登録日2016-08-16
公開日2017-05-31
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the Enterovirus 71 3C Protease in Complex with NK-1.8k and Indications for the Development of Antienterovirus Protease Inhibitor
Antimicrob. Agents Chemother., 61, 2017
6LJ9
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BU of 6lj9 by Molmil
Crystal Structure of Se-Met ASFV pS273R protease
分子名称: Cysteine protease S273R
著者Li, G.B, Liu, X.X, Chen, C, Guo, Y.
登録日2019-12-13
公開日2020-02-26
最終更新日2020-05-13
実験手法X-RAY DIFFRACTION (2.307 Å)
主引用文献Crystal Structure of African Swine Fever Virus pS273R Protease and Implications for Inhibitor Design.
J.Virol., 94, 2020

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