2VL5
 
 | | Structure of anti-collagen type II FAb CIIC1 | | Descriptor: | CIIC1 ANTICOLLAGEN FAB | | Authors: | Uysal, H, Sehnert, B, Nandakumar, K.S, Boiers, U, Burkhardt, H, Holmdahl, R, Thunnissen, M.M. | | Deposit date: | 2008-01-08 | | Release date: | 2008-03-18 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The Crystal Structure of the Pathogenic Collagen Type II-Specific Mouse Monoclonal Antibody Ciic1 Fab: Structure to Function Analysis.
Mol.Immunol., 45, 2008
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2W60
 | | Anti citrullinated Collagen type 2 antibody acc4 | | Descriptor: | ANTI-CITRULLINATED COLLAGEN TYPE II FAB ACC4, NITRATE ION | | Authors: | Uysal, H, Bockermann, R, Nandakumar, K.S, Sehnert, B, Bajtner, E, Engstrom, A, Serre, G, Burkhardt, H, Thunnissen, M.M.G.M, Holmdahl, R. | | Deposit date: | 2008-12-16 | | Release date: | 2009-02-24 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis.
J. Exp. Med., 206, 2009
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2W65
 | | Anti citrullinated Collagen type 2 antibody acc4 in complex with a citrullinated peptide | | Descriptor: | ANTI-CITRULLINATED COLLAGEN TYPE II FAB ACC4, COLLAGEN DERIVED PEPTIDE PCII-CIT1, SULFATE ION | | Authors: | Uysal, H, Bockermann, R, Nandakumar, K.S, Sehnert, B, Bajtner, E, Engstrom, A, Serre, G, Burkhardt, H, Thunnissen, M.M.G.M, Holmdahl, R. | | Deposit date: | 2008-12-17 | | Release date: | 2009-02-24 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis.
J. Exp. Med., 206, 2009
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2Y5T
 | | Crystal structure of the pathogenic autoantibody CIIC1 in complex with the triple-helical C1 peptide | | Descriptor: | C1, CHLORIDE ION, CIIC1 FAB FRAGMENT HEAVY CHAIN, ... | | Authors: | Dobritzsch, D, Lindh, I, Schneider, N, Uysal, H, Nandakumar, K.S, Burkhardt, H, Schneider, G, Holmdahl, R. | | Deposit date: | 2011-01-17 | | Release date: | 2011-12-14 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of an Arthritogenic Anticollagen Immune Complex.
Arthritis Rheum., 63, 2011
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7O00
 | | Crystal structure of HLA-DR4 in complex with a HSP70 peptide | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chaperone protein DnaK, ... | | Authors: | Ge, C, Holmdahl, R. | | Deposit date: | 2021-03-25 | | Release date: | 2022-05-11 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.24 Å) | | Cite: | Key interactions in the trimolecular complex consisting of the rheumatoid arthritis-associated DRB1*04:01 molecule, the major glycosylated collagen II peptide and the T-cell receptor.
Ann Rheum Dis, 81, 2022
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7NZH
 | | Crystal structure of HLA-DR4 in complex with a citrullinated cilp peptide | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, ... | | Authors: | Ge, C, Holmdahl, R. | | Deposit date: | 2021-03-24 | | Release date: | 2022-05-11 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.831 Å) | | Cite: | Key interactions in the trimolecular complex consisting of the rheumatoid arthritis-associated DRB1*04:01 molecule, the major glycosylated collagen II peptide and the T-cell receptor.
Ann Rheum Dis, 81, 2022
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7NZF
 | | Crystal structure of HLA-DR4 in complex with a mutated human collagen type II peptide | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ... | | Authors: | Ge, C, Dobritzsch, D, Holmdahl, R. | | Deposit date: | 2021-03-24 | | Release date: | 2022-05-11 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Key interactions in the trimolecular complex consisting of the rheumatoid arthritis-associated DRB1*04:01 molecule, the major glycosylated collagen II peptide and the T-cell receptor.
Ann Rheum Dis, 81, 2022
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7NZE
 | | Crystal structure of HLA-DR4 in complex with a human collagen type II peptide | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Collagen alpha-1(II) chain, GLYCEROL, ... | | Authors: | Ge, C, Dobritzsch, D, Holmdahl, R. | | Deposit date: | 2021-03-24 | | Release date: | 2022-06-08 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Key interactions in the trimolecular complex consisting of the rheumatoid arthritis-associated DRB1*04:01 molecule, the major glycosylated collagen II peptide and the T-cell receptor.
Ann Rheum Dis, 81, 2022
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5MUB
 | | ACC1 Fab fragment in complex with citrullinated C1 epitope of CII (CG05) | | Descriptor: | ACC1 Fab fragment heavy chain, ACC1 Fab fragment light chain, triple-helical peptide containing the citrullinated C1 epitope of collagen type II,Collagen alpha-1(II) chain,triple-helical peptide containing the citrullinated C1 epitope of collagen type II | | Authors: | Dobritzsch, D, Holmdahl, R, Ge, C. | | Deposit date: | 2017-01-13 | | Release date: | 2017-07-19 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage.
JCI Insight, 2, 2017
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5MV4
 | | ACC1 Fab fragment in complex with citrullinated CII616-639 epitope of collagen type II (ptm23) | | Descriptor: | ACC1 antibody Fab fragment, heavy chain, light chain, ... | | Authors: | Dobritzsch, D, Holmdahl, R, Ge, C. | | Deposit date: | 2017-01-15 | | Release date: | 2017-07-19 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage.
JCI Insight, 2, 2017
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5MU0
 | | ACC1 Fab fragment in complex with citrullinated C1 epitope of CII (IA03) | | Descriptor: | IA03 peptide containing the citrullinated C1 epitope of collagen type II,Collagen alpha-1(II) chain,IA03 peptide containing the citrullinated C1 epitope of collagen type II, heavy chain of ACC1 antibody Fab fragment, light chain of ACC1 antibody Fab fragment | | Authors: | Dobritzsch, D, Holmdahl, R, Ge, C. | | Deposit date: | 2017-01-11 | | Release date: | 2017-07-19 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage.
JCI Insight, 2, 2017
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5MV3
 | | ACC1 Fab fragment in complex with CII583-591 (CG10) | | Descriptor: | heavy chain of ACC1 Fab fragment, light chain of ACC1 Fab fragment, synthetic peptide containing the CII583-591 epitope of collagen type II,Collagen alpha-1(II) chain,synthetic peptide containing the CII583-591 epitope of collagen type II, | | Authors: | Dobritzsch, D, Holmdahl, R, Ge, C. | | Deposit date: | 2017-01-15 | | Release date: | 2017-07-19 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage.
JCI Insight, 2, 2017
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5MU2
 | | ACC1 Fab fragment in complex with CII583-591 (CG10) | | Descriptor: | ACC1 Fab fragment heavy chain, ACC1 Fab fragment light chain, synthetic peptide containing the CII583-591 epitope of collagen type II | | Authors: | Dobritzsch, D, Holmdahl, R, Ge, C. | | Deposit date: | 2017-01-12 | | Release date: | 2017-07-19 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage.
JCI Insight, 2, 2017
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