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4O69
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BU of 4o69 by Molmil
Human cyclic GMP-AMP synthase (cGAS) in complex with sulfate ion
Descriptor: Cyclic GMP-AMP synthase, SULFATE ION, ZINC ION
Authors:Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J.
Deposit date:2013-12-20
Release date:2014-02-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.252 Å)
Cite:The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Cell Rep, 6, 2014
4O6A
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BU of 4o6a by Molmil
Mouse cyclic GMP-AMP synthase (cGAS) in complex with DNA
Descriptor: Cyclic GMP-AMP synthase, DNA1, DNA2, ...
Authors:Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J.
Deposit date:2013-12-20
Release date:2014-02-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.859 Å)
Cite:The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Cell Rep, 6, 2014
5DHF
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BU of 5dhf by Molmil
Crystal Structure of hRio2 NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: CHLORIDE ION, Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y, Chook, Y.M.
Deposit date:2015-08-30
Release date:2015-09-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.285 Å)
Cite:Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
5DH9
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BU of 5dh9 by Molmil
Crystal Structure of PKI NES Flip Mutant Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Engineered Nuclear Export Signal Peptide (PKINES-Flip3 mutant), Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y, Chook, Y.M.
Deposit date:2015-08-30
Release date:2015-09-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
5DHA
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BU of 5dha by Molmil
Crystal Structure of CPEB4 NES Reverse Mutant Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Engineered Nuclear Export Signal Peptide (CPEB4 NES reverse mutant), Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y, Chook, Y.M.
Deposit date:2015-08-30
Release date:2015-09-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
5DIF
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BU of 5dif by Molmil
Crystal Structure of CPEB4 NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: CHLORIDE ION, Cytoplasmic polyadenylation element-binding protein 4, Exportin-1, ...
Authors:Fung, H.Y, Chook, Y.M.
Deposit date:2015-08-31
Release date:2015-09-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.092 Å)
Cite:Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
5DI9
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BU of 5di9 by Molmil
Crystal Structure of hRio2 NES Reverse Mutant Peptide in complex with CRM1-Ran-RanBP1
Descriptor: CHLORIDE ION, Engineered Nuclear Export Signal Peptide (hRio2 NES reverse mutant), Exportin-1, ...
Authors:Fung, H.Y, Chook, Y.M.
Deposit date:2015-08-31
Release date:2015-09-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
5E6P
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BU of 5e6p by Molmil
PlexinB2 cytoplasmic region/PDZ-RhoGEF PDZ domain complex
Descriptor: Plexin-B2, Rho guanine nucleotide exchange factor 11
Authors:Pascoe, H.G, Zhang, X.
Deposit date:2015-10-10
Release date:2015-11-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.215 Å)
Cite:Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.
Proc.Natl.Acad.Sci.USA, 112, 2015
4U3J
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BU of 4u3j by Molmil
TOG2:alpha/beta-tubulin complex
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein STU2, ...
Authors:Ayaz, P, Rice, L.M.
Deposit date:2014-07-22
Release date:2014-08-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:A tethered delivery mechanism explains the catalytic action of a microtubule polymerase.
Elife, 3, 2014
5WC2
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BU of 5wc2 by Molmil
Crystal Structure of ADP-bound human TRIP13
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Pachytene checkpoint protein 2 homolog
Authors:Jeong, B.-C, Luo, X.
Deposit date:2017-06-29
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanistic insight into TRIP13-catalyzed Mad2 structural transition and spindle checkpoint silencing.
Nat Commun, 8, 2017
6AR0
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BU of 6ar0 by Molmil
Structure of human SLMAP FHA domain
Descriptor: Sarcolemmal membrane-associated protein
Authors:Ni, L, Luo, X.
Deposit date:2017-08-21
Release date:2018-07-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.
Elife, 6, 2017
6BC0
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BU of 6bc0 by Molmil
A Complex between PH Domain of p190RhoGEF and Activated RhoA Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rho guanine nucleotide exchange factor 28, ...
Authors:Chen, Z, Sternweis, P.C.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.
J. Struct. Biol., 202, 2018
6AR2
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BU of 6ar2 by Molmil
Structure of human SLMAP FHA domain in complex with pMST2
Descriptor: ASP-GLY-TPO-MET-LYS-ARG, Sarcolemmal membrane-associated protein
Authors:Osinski, A, Ni, L, Luo, X.
Deposit date:2017-08-21
Release date:2018-07-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.
Elife, 6, 2017
6BC1
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BU of 6bc1 by Molmil
A Complex between PH Domain of p190RhoGEF and Activated Rac1 Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1, ...
Authors:Chen, Z, Sternweis, P.C.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.
J. Struct. Biol., 202, 2018
2QJO
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BU of 2qjo by Molmil
crystal structure of a bifunctional NMN adenylyltransferase/ADP ribose pyrophosphatase (NadM) complexed with ADPRP and NAD from Synechocystis sp.
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, Bifunctional NMN adenylyltransferase/Nudix hydrolase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Huang, N, Sorci, L, Zhang, X, Brautigan, C, Raffaelli, N, Magni, G, Grishin, N.V, Osterman, A, Zhang, H.
Deposit date:2007-07-08
Release date:2008-03-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Bifunctional NMN Adenylyltransferase/ADP-Ribose Pyrophosphatase: Structure and Function in Bacterial NAD Metabolism.
Structure, 16, 2008
2QJT
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BU of 2qjt by Molmil
Crystal structure of a bifunctional NMN adenylyltransferase/ADP ribose pyrophosphatase complexed with AMP and MN ion from Francisella tularensis
Descriptor: ADENOSINE MONOPHOSPHATE, MANGANESE (II) ION, Nicotinamide-nucleotide adenylyltransferase
Authors:Huang, N, Sorci, L, Zhang, X, Brautigan, C, Raffaelli, N, Magni, G, Grishin, N.V, Osterman, A, Zhang, H.
Deposit date:2007-07-09
Release date:2008-03-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Bifunctional NMN Adenylyltransferase/ADP-Ribose Pyrophosphatase: Structure and Function in Bacterial NAD Metabolism.
Structure, 16, 2008
2R5W
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BU of 2r5w by Molmil
Crystal structure of a bifunctional NMN adenylyltransferase/ADP ribose pyrophosphatase from Francisella tularensis
Descriptor: CHLORIDE ION, MAGNESIUM ION, Nicotinamide-nucleotide adenylyltransferase
Authors:Huang, N, Sorci, L, Zhang, X, Brautigan, C, Li, X, Raffaelli, N, Grishin, N, Osterman, A, Zhang, H.
Deposit date:2007-09-04
Release date:2008-03-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Bifunctional NMN Adenylyltransferase/ADP-Ribose Pyrophosphatase: Structure and Function in Bacterial NAD Metabolism.
Structure, 16, 2008
7CYL
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BU of 7cyl by Molmil
Crystal structure of Karyopherin-beta2 in complex with FUS PY-NLS(P525L)
Descriptor: RNA-binding protein FUS, Transportin-1
Authors:Yoshizawa, T, Chook, Y.M.
Deposit date:2020-09-03
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mechanism of karyopherin-beta 2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X).
Sci Rep, 11, 2021
3SEO
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BU of 3seo by Molmil
Crystal structure of VopL C terminal domain
Descriptor: CHLORIDE ION, VopL C terminal domain protein
Authors:Yu, B, Rosen, M.K, Tomchick, D.R.
Deposit date:2011-06-10
Release date:2011-08-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.305 Å)
Cite:Mechanism of actin filament nucleation by the bacterial effector VopL.
Nat.Struct.Mol.Biol., 18, 2011
6VII
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BU of 6vii by Molmil
Crystal structure of mouse RABL3 in complex with GTPgammaS
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rab-like protein 3
Authors:Su, L, Tomchick, D.R, Beutler, B.
Deposit date:2020-01-13
Release date:2020-04-08
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VIK
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BU of 6vik by Molmil
Crystal structure of mouse xm RABL3 in complex with GTPgammsS
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rab-like protein 3
Authors:Su, L, Tomchick, D.R, Beutler, B.
Deposit date:2020-01-13
Release date:2020-04-08
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VIH
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BU of 6vih by Molmil
The ligand-free structure of mouse RABL3
Descriptor: Rab-like protein 3
Authors:Su, L, Tomchick, D.R, Beutler, B.
Deposit date:2020-01-13
Release date:2020-04-08
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.993 Å)
Cite:Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VIJ
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BU of 6vij by Molmil
Crystal structure of mouse RABL3 in complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rab-like protein 3
Authors:Su, L, Tomchick, D.R, Beutler, B.
Deposit date:2020-01-13
Release date:2020-04-08
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.
Proc.Natl.Acad.Sci.USA, 117, 2020
6X2W
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BU of 6x2w by Molmil
Crystal Structure of PKINES peptide bound to CRM1(E571K)
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Baumhardt, J.M.
Deposit date:2020-05-21
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020
6X2U
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BU of 6x2u by Molmil
Crystal Structure of PKINES peptide bound to CRM1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Baumhardt, J.M.
Deposit date:2020-05-21
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020

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数据于2024-05-22公开中

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