7ZH2
 
 | | SARS CoV Spike protein, Closed C1 conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ... | | Authors: | Toelzer, C, Gupta, K, Yadav, S.K.N, Buzas, D, Borucu, U, Schaffitzel, C, Berger, I. | | Deposit date: | 2022-04-05 | | Release date: | 2023-02-15 | | Method: | ELECTRON MICROSCOPY (2.71 Å) | | Cite: | The free fatty acid-binding pocket is a conserved hallmark in pathogenic beta-coronavirus spike proteins from SARS-CoV to Omicron.
Sci Adv, 8, 2022
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7ZH5
 | | SARS CoV Spike protein, Open conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin | | Authors: | Toelzer, C, Gupta, K, Yadav, S.K.N, Buzas, D, Borucu, U, Schaffitzel, C, Berger, I. | | Deposit date: | 2022-04-05 | | Release date: | 2023-02-15 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | The free fatty acid-binding pocket is a conserved hallmark in pathogenic beta-coronavirus spike proteins from SARS-CoV to Omicron.
Sci Adv, 8, 2022
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7ZH1
 | | SARS CoV Spike protein, Closed C3 conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ... | | Authors: | Toelzer, C, Gupta, K, Yadav, S.K.N, Buzas, D, Borucu, U, Schaffitzel, C, Berger, I. | | Deposit date: | 2022-04-05 | | Release date: | 2023-02-15 | | Method: | ELECTRON MICROSCOPY (2.48 Å) | | Cite: | The free fatty acid-binding pocket is a conserved hallmark in pathogenic beta-coronavirus spike proteins from SARS-CoV to Omicron.
Sci Adv, 8, 2022
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8F2R
 | | Human CCC complex | | Descriptor: | COMM domain-containing protein 1, COMM domain-containing protein 10, COMM domain-containing protein 2, ... | | Authors: | Healy, M.D, McNally, K.E, Butkovic, R, Chilton, M, Kato, K, Sacharz, J, McConville, C, Moody, E.R.R, Shaw, S, Planelles-Herrero, V.J, Kadapalakere, S.Y, Ross, J, Borucu, U, Palmer, C.S, Chen, K, Croll, T.I, Hall, R.J, Caruana, N.J, Ghai, R, Nguyen, T.H.D, Heesom, K.J, Saitoh, S, Berger, I, Berger-Schaffitzel, C, Williams, T.A, Stroud, D.A, Derivery, E, Collins, B.M, Cullen, P.J. | | Deposit date: | 2022-11-08 | | Release date: | 2023-05-24 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Cell, 186, 2023
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8F2U
 | | Human CCC complex | | Descriptor: | COMM domain-containing protein 1, COMM domain-containing protein 10, COMM domain-containing protein 2, ... | | Authors: | Healy, M.D, McNally, K.E, Butkovic, R, Chilton, M, Kato, K, Sacharz, J, McConville, C, Moody, E.R.R, Shaw, S, Planelles-Herrero, V.J, Kadapalakere, S.Y, Ross, J, Borucu, U, Palmer, C.S, Chen, K, Croll, T.I, Hall, R.J, Caruana, N.J, Ghai, R, Nguyen, T.H.D, Heesom, K.J, Saitoh, S, Berger, I, Berger-Schaffitzel, C, Williams, T.A, Stroud, D.A, Derivery, E, Collins, B.M, Cullen, P.J. | | Deposit date: | 2022-11-08 | | Release date: | 2023-05-24 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.53 Å) | | Cite: | Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Cell, 186, 2023
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7ODL
 | | SARS CoV-2 Spike protein, Bristol UK Deletion variant, Closed conformation, C1 symmetry | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, Spike glycoprotein | | Authors: | Toelzer, C, Gupta, K, Yadav, S.K.N, Borucu, U, Schaffitzel, C, Berger, I. | | Deposit date: | 2021-04-29 | | Release date: | 2022-01-26 | | Method: | ELECTRON MICROSCOPY (3.03 Å) | | Cite: | Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2.
Nat Commun, 13, 2022
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7OD3
 | | SARS CoV-2 Spike protein, Bristol UK Deletion variant, Closed conformation, C3 symmetry | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, Spike glycoprotein | | Authors: | Toelzer, C, Gupta, K, Yadav, S.K.N, Borucu, U, Schaffitzel, C, Berger, I. | | Deposit date: | 2021-04-28 | | Release date: | 2022-01-26 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2.
Nat Commun, 13, 2022
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8QBX
 | | Chimeric Adenovirus-derived dodecamer | | Descriptor: | Penton protein | | Authors: | Buzas, D, Borucu, U, Bufton, J, Kapadalakere, S.Y, Toelzer, C. | | Deposit date: | 2023-08-25 | | Release date: | 2023-12-27 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | Engineering the ADDobody protein scaffold for generation of high-avidity ADDomer super-binders.
Structure, 32, 2024
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8C9N
 | | MiniCoV-ADDomer, a SARS-CoV-2 epitope presenting viral like particle | | Descriptor: | Penton protein | | Authors: | Bufton, J.C, Capin, J, Boruku, U, Garzoni, F, Schaffitzel, C, Berger, I. | | Deposit date: | 2023-01-23 | | Release date: | 2023-12-06 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.36 Å) | | Cite: | In vitro generated antibodies guide thermostable ADDomer nanoparticle design for nasal vaccination and passive immunization against SARS-CoV-2.
Antib Ther, 6, 2023
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8COI
 | | Human adenovirus-derived synthetic ADDobody binder | | Descriptor: | ADDobody | | Authors: | Buzas, D, Toelzer, C, Gupta, K, Berger-Schaffitzel, C, Berger, I. | | Deposit date: | 2023-02-28 | | Release date: | 2023-12-27 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.17 Å) | | Cite: | Engineering the ADDobody protein scaffold for generation of high-avidity ADDomer super-binders.
Structure, 32, 2024
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6ZB4
 | | SARS CoV-2 Spike protein, Closed conformation, C1 symmetry | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ... | | Authors: | Toelzer, C, Gupta, K, Yadav, S.K.N, Burucu, U, Schaffitzel, C, Berger, I. | | Deposit date: | 2020-06-06 | | Release date: | 2020-09-30 | | Last modified: | 2020-11-18 | | Method: | ELECTRON MICROSCOPY (3.03 Å) | | Cite: | Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein.
Science, 370, 2020
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6ZB5
 | | SARS CoV-2 Spike protein, Closed conformation, C3 symmetry | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ... | | Authors: | Toelzer, C, Gupta, K, Yadav, S.K.N, Burucu, U, Schaffitzel, C, Berger, I. | | Deposit date: | 2020-06-07 | | Release date: | 2020-09-30 | | Last modified: | 2020-11-18 | | Method: | ELECTRON MICROSCOPY (2.85 Å) | | Cite: | Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein.
Science, 370, 2020
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8ESD
 | | Crystal structure of COMMD7-COMMD9-COMMD5-COMMD10 tetramer | | Descriptor: | COMM domain-containing protein 10, COMM domain-containing protein 5, COMM domain-containing protein 7, ... | | Authors: | Healy, M.D, Collins, B.M. | | Deposit date: | 2022-10-13 | | Release date: | 2023-05-24 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.33 Å) | | Cite: | Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Cell, 186, 2023
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8ESE
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7NWI
 | | Mammalian pre-termination 80S ribosome with Empty-A site bound by Blasticidin S | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA+BlaS, 40S ribosomal protein S11, ... | | Authors: | Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. | | Deposit date: | 2021-03-16 | | Release date: | 2021-07-07 | | Last modified: | 2023-01-11 | | Method: | ELECTRON MICROSCOPY (3.13 Å) | | Cite: | Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA.
Nucleic Acids Res., 49, 2021
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7NWG
 | | Mammalian pre-termination 80S ribosome with Hybrid P/E- and A/P-site tRNA's bound by Blasticidin S. | | Descriptor: | 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ... | | Authors: | Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. | | Deposit date: | 2021-03-16 | | Release date: | 2021-07-07 | | Last modified: | 2023-01-11 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA.
Nucleic Acids Res., 49, 2021
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7NWH
 | | Mammalian pre-termination 80S ribosome with eRF1 and eRF3 bound by Blasticidin S. | | Descriptor: | 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ... | | Authors: | Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. | | Deposit date: | 2021-03-16 | | Release date: | 2021-07-07 | | Last modified: | 2023-01-11 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA.
Nucleic Acids Res., 49, 2021
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8QB3
 | | ADDobody zinc containing condition | | Descriptor: | ADDobody, ZINC ION | | Authors: | Buzas, D, Toelzer, C, Berger, I, Schaffitzel, C. | | Deposit date: | 2023-08-24 | | Release date: | 2023-12-27 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Engineering the ADDobody protein scaffold for generation of high-avidity ADDomer super-binders.
Structure, 32, 2024
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8QAA
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8QAB
 | | X-ray crystal structure of a de novo designed antiparallel coiled-coil hexameric alpha-helical barrel with 4 heptad repeats, apCCHex | | Descriptor: | 1-methoxy-2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethane, apCCHex | | Authors: | Naudin, E.N, Albanese, K.I, Petrenas, R, Woolfson, D.N. | | Deposit date: | 2023-08-22 | | Release date: | 2024-07-03 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Rationally seeded computational protein design of ɑ-helical barrels.
Nat.Chem.Biol., 2024
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8QAI
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8QAH
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8QKD
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8QAD
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8QAF
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