7ZH1

SARS CoV Spike protein, Closed C3 conformation

Summary for 7ZH1

Entry DOI	10.2210/pdb7zh1/pdb
EMDB information	14717
Descriptor	Spike glycoprotein,Fibritin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ... (4 entities in total)
Functional Keywords	sars-cov, viral protein, spike
Biological source	Severe acute respiratory syndrome-related coronavirus More
Total number of polymer chains	3
Total formula weight	423360.34
Authors	Toelzer, C.,Gupta, K.,Yadav, S.K.N.,Buzas, D.,Borucu, U.,Schaffitzel, C.,Berger, I. (deposition date: 2022-04-05, release date: 2023-02-15)
Primary citation	Toelzer, C.,Gupta, K.,Yadav, S.K.N.,Hodgson, L.,Williamson, M.K.,Buzas, D.,Borucu, U.,Powers, K.,Stenner, R.,Vasileiou, K.,Garzoni, F.,Fitzgerald, D.,Payre, C.,Gautam, G.,Lambeau, G.,Davidson, A.D.,Verkade, P.,Frank, M.,Berger, I.,Schaffitzel, C. The free fatty acid-binding pocket is a conserved hallmark in pathogenic beta-coronavirus spike proteins from SARS-CoV to Omicron. Sci Adv, 8:eadc9179-eadc9179, 2022 Cited by PubMed: 36417532 DOI: 10.1126/sciadv.adc9179 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.48 Å)

Structure validation