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3MFG
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BU of 3mfg by Molmil
Crystal structure of Toxic Shock Syndrome Toxin 1 (TSST-1) in complex with the human T cell receptor beta chain Vbeta2.1 (EP-8)
Descriptor: GLYCEROL, SULFATE ION, Toxic shock syndrome toxin-1, ...
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2010-04-02
Release date:2010-11-24
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Crystal structure of Toxic Shock Syndrome Toxin 1 (TSST-1) in complex with the human T cell receptor beta chain Vbeta2.1 (EP-8)
To be Published
4Y88
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BU of 4y88 by Molmil
Crystal structure of the N-terminal domain of CEACAM8
Descriptor: 1,3-PROPANDIOL, CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 8, ...
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2015-02-16
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Diverse oligomeric states of CEACAM IgV domains.
Proc.Natl.Acad.Sci.USA, 112, 2015
4Y8A
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BU of 4y8a by Molmil
Crystal Structure of the N-terminal domain of CEACAM6
Descriptor: Carcinoembryonic antigen-related cell adhesion molecule 6, GLYCEROL, ZINC ION
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2015-02-16
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Diverse oligomeric states of CEACAM IgV domains.
Proc.Natl.Acad.Sci.USA, 112, 2015
4Y89
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BU of 4y89 by Molmil
Crystal structure of the N-terminal domain of CEACAM7
Descriptor: CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 7
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2015-02-16
Release date:2015-09-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structure of the N-terminal dimerization domain of CEACAM7.
Acta Crystallogr.,Sect.F, 71, 2015
4YIQ
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BU of 4yiq by Molmil
Structure of the CEACAM6-CEACAM8 heterodimer
Descriptor: CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 6, Carcinoembryonic antigen-related cell adhesion molecule 8, ...
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2015-03-02
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Diverse oligomeric states of CEACAM IgV domains.
Proc.Natl.Acad.Sci.USA, 112, 2015
6AW2
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BU of 6aw2 by Molmil
Crystal structure of the HopQ-CEACAM1 complex
Descriptor: Carcinoembryonic antigen-related cell adhesion molecule 1, HopQ
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2017-09-05
Release date:2018-05-16
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
EMBO J., 37, 2018
6AVZ
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BU of 6avz by Molmil
Crystal structure of the HopQ-CEACAM3 WT complex
Descriptor: CALCIUM ION, Carcinoembryonic antigen-related cell adhesion molecule 3, HopQ, ...
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2017-09-05
Release date:2018-05-16
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
EMBO J., 37, 2018
6AW1
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BU of 6aw1 by Molmil
Crystal structure of CEACAM3
Descriptor: CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 3, DI(HYDROXYETHYL)ETHER, ...
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2017-09-05
Release date:2018-05-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
EMBO J., 37, 2018
6AW3
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BU of 6aw3 by Molmil
Crystal structure of the HopQ-CEACAM3 L44Q complex
Descriptor: Carcinoembryonic antigen-related cell adhesion molecule 3, HopQ
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2017-09-05
Release date:2018-05-16
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
EMBO J., 37, 2018
6AW0
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BU of 6aw0 by Molmil
Crystal structure of CEACAM3 L44Q
Descriptor: CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 3, GLYCEROL, ...
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2017-09-05
Release date:2018-05-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
EMBO J., 37, 2018
7TVF
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BU of 7tvf by Molmil
Crystal structure of the SHOC2-MRAS-PP1CA (SMP) complex to a resolution of 2.17 Angstrom
Descriptor: CHLORIDE ION, GLYCEROL, Leucine-rich repeat protein SHOC-2, ...
Authors:Bonsor, D.A, Simanshu, D.K.
Deposit date:2022-02-04
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structure of the SHOC2-MRAS-PP1C complex provides insights into RAF activation and Noonan syndrome.
Nat.Struct.Mol.Biol., 29, 2022
7TVG
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BU of 7tvg by Molmil
Crystal Structure of SHOC2 to a resolution of 2.4 Angstrom
Descriptor: CHLORIDE ION, Leucine-rich repeat protein SHOC-2, SULFATE ION
Authors:Bonsor, D.A, Simanshu, D.K.
Deposit date:2022-02-04
Release date:2022-05-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the SHOC2-MRAS-PP1C complex provides insights into RAF activation and Noonan syndrome.
Nat.Struct.Mol.Biol., 29, 2022
3R8B
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BU of 3r8b by Molmil
Crystal structure of Staphylococcal Enterotoxin B in complex with an affinity matured mouse TCR VBeta8.2 protein, G5-8
Descriptor: CHLORIDE ION, Enterotoxin type B, G5-8, ...
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2011-03-23
Release date:2011-04-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Molecular basis of a million-fold affinity maturation process in a protein-protein interaction.
J.Mol.Biol., 411, 2011
8CXJ
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BU of 8cxj by Molmil
The IgI3 domain of R28 protein from S. pyogenes bound to CEACAM1
Descriptor: CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 1, GLYCEROL, ...
Authors:Bonsor, D.A, McCarthy, A.J.
Deposit date:2022-05-21
Release date:2023-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Human CEACAM1 is targeted by a Streptococcus pyogenes adhesin implicated in puerperal sepsis pathogenesis.
Nat Commun, 14, 2023
4X5U
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BU of 4x5u by Molmil
X-ray crystal structure of CagL at pH 4.2
Descriptor: Cag pathogenicity island protein (Cag18)
Authors:Sundberg, E.J, Bonsor, D.A, Diederichs, K.
Deposit date:2014-12-05
Release date:2015-04-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Integrin Engagement by the Helical RGD Motif of the Helicobacter pylori CagL Protein Is Regulated by pH-induced Displacement of a Neighboring Helix.
J.Biol.Chem., 290, 2015
6V3P
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BU of 6v3p by Molmil
The BIgI domain of beta protein from S. agalactiae bound to CEACAM1
Descriptor: Carcinoembryonic antigen-related cell adhesion molecule 1, GLYCEROL, IgA FC receptor, ...
Authors:Bonsor, D.A, McCarthy, A.J.
Deposit date:2019-11-26
Release date:2020-12-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Bacterial protein domains with a novel Ig-like fold target human CEACAM receptors.
Embo J., 40, 2021
8EQ5
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BU of 8eq5 by Molmil
Crystal structure of the N-terminal kinase domain of RSK2 in complex with SPRED2 (131-160)
Descriptor: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside, Ribosomal protein S6 kinase alpha-3, Sprouty-related, ...
Authors:Bonsor, D.A, Lopez, J, McCormick, F, Simanshu, D.K.
Deposit date:2022-10-07
Release date:2023-04-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The ribosomal S6 kinase 2 (RSK2)-SPRED2 complex regulates the phosphorylation of RSK substrates and MAPK signaling.
J.Biol.Chem., 299, 2023
2W8B
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BU of 2w8b by Molmil
Crystal structure of processed TolB in complex with Pal
Descriptor: ACETATE ION, GLYCEROL, PEPTIDOGLYCAN-ASSOCIATED LIPOPROTEIN, ...
Authors:Sharma, A, Bonsor, D.A, Kleanthous, C.
Deposit date:2009-01-15
Release date:2009-02-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Allosteric Beta-Propeller Signalling in Tolb and its Manipulation by Translocating Colicins.
Embo J., 28, 2009
2HQS
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BU of 2hqs by Molmil
Crystal structure of TolB/Pal complex
Descriptor: ACETATE ION, GLYCEROL, Peptidoglycan-associated lipoprotein, ...
Authors:Grishkovskaya, I, Bonsor, D.A, Kleanthous, C, Dodson, E.J.
Deposit date:2006-07-19
Release date:2007-04-03
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular mimicry enables competitive recruitment by a natively disordered protein.
J.Am.Chem.Soc., 129, 2007
2IVZ
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BU of 2ivz by Molmil
Structure of TolB in complex with a peptide of the colicin E9 T- domain
Descriptor: CALCIUM ION, COLICIN-E9, PROTEIN TOLB
Authors:Loftus, S.R, Walker, D, Mate, M.J, Bonsor, D.A, James, R, Moore, G.R, Kleanthous, C.
Deposit date:2006-06-23
Release date:2006-08-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Competitive Recruitment of the Periplasmic Translocation Portal Tolb by a Natively Disordered Domain of Colicin E9
Proc.Natl.Acad.Sci.USA, 103, 2006
3QLQ
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BU of 3qlq by Molmil
Crystal structure of Concanavalin A bound to an octa-alpha-mannosyl-octasilsesquioxane cluster
Descriptor: CALCIUM ION, Concanavalin-A, MANGANESE (II) ION, ...
Authors:Sundberg, E.J, Bonsor, D.A, Trastoy, B, Chiara, J.L.
Deposit date:2011-02-03
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Synthesis and Biophysical Study of Disassembling Nano hybrid Bioconjugates with a Cubic Octasilsesquioxane Core
Adv Funct Mater, 22, 2012
6XNT
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BU of 6xnt by Molmil
Crystal structure of I91A mutant of human CEACAM1
Descriptor: Carcinoembryonic antigen-related cell adhesion molecule 1, octyl beta-D-glucopyranoside
Authors:Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S.
Deposit date:2020-07-04
Release date:2021-03-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium.
Commun Biol, 4, 2021
6XO1
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BU of 6xo1 by Molmil
Crystal structure of N97A mutant of human CEACAM1
Descriptor: Carcinoembryonic antigen-related cell adhesion molecule 1, MALONIC ACID
Authors:Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S.
Deposit date:2020-07-05
Release date:2021-03-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.758 Å)
Cite:Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium.
Commun Biol, 4, 2021
6XNW
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BU of 6xnw by Molmil
Crystal structure of V39A mutant of human CEACAM1
Descriptor: Carcinoembryonic antigen-related cell adhesion molecule 1, NICKEL (II) ION
Authors:Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S.
Deposit date:2020-07-04
Release date:2021-03-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium.
Commun Biol, 4, 2021
6XNO
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BU of 6xno by Molmil
Crystal structure of E99A mutant of human CEACAM1
Descriptor: Carcinoembryonic antigen-related cell adhesion molecule 1, MALONIC ACID, octyl beta-D-glucopyranoside
Authors:Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S.
Deposit date:2020-07-03
Release date:2021-03-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium.
Commun Biol, 4, 2021

 

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