8CXJ

The IgI3 domain of R28 protein from S. pyogenes bound to CEACAM1

Summary for 8CXJ

Entry DOI	10.2210/pdb8cxj/pdb
Descriptor	Carcinoembryonic antigen-related cell adhesion molecule 1, Surface protein R28, GLYCEROL, ... (6 entities in total)
Functional Keywords	bacterial, adhesion, cell adhesion
Biological source	Homo sapiens (human) More
Total number of polymer chains	8
Total formula weight	105483.85
Authors	Bonsor, D.A.,McCarthy, A.J. (deposition date: 2022-05-21, release date: 2023-03-15, Last modification date: 2023-10-25)
Primary citation	Catton, E.A.,Bonsor, D.A.,Herrera, C.,Stalhammar-Carlemalm, M.,Lyndin, M.,Turner, C.E.,Soden, J.,van Strijp, J.A.G.,Singer, B.B.,van Sorge, N.M.,Lindahl, G.,McCarthy, A.J. Human CEACAM1 is targeted by a Streptococcus pyogenes adhesin implicated in puerperal sepsis pathogenesis. Nat Commun, 14:2275-2275, 2023 Cited by PubMed: 37080973 DOI: 10.1038/s41467-023-37732-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.05 Å)

Structure validation