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4I1N
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BU of 4i1n by Molmil
R104A-ca1697 nanobody binding to the binary DHFR.folate complex
分子名称: Dihydrofolate reductase, FOLIC ACID, Protein ca1697 (nanobody)
著者Oyen, D, Steyaert, J, Barlow, J.N.
登録日2012-11-21
公開日2013-11-27
実験手法X-RAY DIFFRACTION (1.888 Å)
主引用文献Exploring an alternative antibody interaction mechanism
To be Published
4I13
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BU of 4i13 by Molmil
Nanobody ca1697 binding to the DHFR.folate binary complex
分子名称: Dihydrofolate reductase, FOLIC ACID, Protein ca1697 (nanobody)
著者Oyen, D, Steyaert, J, Barlow, J.N.
登録日2012-11-19
公開日2013-11-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Exploring an alternative antibody interaction mechanism
To be Published
1KCZ
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BU of 1kcz by Molmil
Crystal Structure of beta-methylaspartase from Clostridium tetanomorphum. Mg-complex.
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, beta-methylaspartase
著者Asuncion, M, Blankenfeldt, W, Barlow, J.N, Gani, D, Naismith, J.H.
登録日2001-11-12
公開日2001-12-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structure of 3-methylaspartase from Clostridium tetanomorphum functions via the common enolase chemical step.
J.Biol.Chem., 277, 2002
1KD0
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BU of 1kd0 by Molmil
Crystal Structure of beta-methylaspartase from Clostridium tetanomorphum. Apo-structure.
分子名称: 1,2-ETHANEDIOL, beta-methylaspartase
著者Asuncion, M, Blankenfeldt, W, Barlow, J.N, Gani, D, Naismith, J.H.
登録日2001-11-12
公開日2001-12-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structure of 3-methylaspartase from Clostridium tetanomorphum functions via the common enolase chemical step.
J.Biol.Chem., 277, 2002
3K74
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BU of 3k74 by Molmil
Disruption of protein dynamics by an allosteric effector antibody
分子名称: Dihydrofolate reductase, Nanobody
著者Oyen, D, Srinivasan, V, Steyaert, J, Barlow, J.
登録日2009-10-12
公開日2010-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Constraining enzyme conformational change by an antibody leads to hyperbolic inhibition.
J.Mol.Biol., 407, 2011
4EIG
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BU of 4eig by Molmil
CA1698 camel antibody fragment in complex with DHFR
分子名称: CA1698 camel antibody fragment, Dihydrofolate reductase
著者Oyen, D, Srinivasan, V.
登録日2012-04-05
公開日2013-04-24
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihyrofolate reductase of Escherichia coli.
Biochim.Biophys.Acta, 1834, 2013
4EIZ
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BU of 4eiz by Molmil
Structure of Nb113 bound to apoDHFR
分子名称: Dihydrofolate reductase, Nb113 Camel antibody fragment
著者Oyen, D, Srinivasan, V.
登録日2012-04-06
公開日2013-04-24
最終更新日2013-10-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihyrofolate reductase of Escherichia coli.
Biochim.Biophys.Acta, 1834, 2013
4EJ1
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BU of 4ej1 by Molmil
Binding of Nb113 camelid antibody fragment with the binary DHFR:folate complex
分子名称: Dihydrofolate reductase, FOLIC ACID, Nb113 camelid antibody fragment, ...
著者Oyen, D, Srinivasan, V.
登録日2012-04-06
公開日2013-04-24
最終更新日2013-10-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihyrofolate reductase of Escherichia coli.
Biochim.Biophys.Acta, 1834, 2013
4FHB
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BU of 4fhb by Molmil
Enhancing DHFR catalysis by binding of an allosteric regulator nanobody (Nb179)
分子名称: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Oyen, D.
登録日2012-06-06
公開日2013-04-24
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihyrofolate reductase of Escherichia coli.
Biochim.Biophys.Acta, 1834, 2013

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件を2024-05-15に公開中

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