4I13

Nanobody ca1697 binding to the DHFR.folate binary complex

Summary for 4I13

Related4I1N
DescriptorDihydrofolate reductase, Protein ca1697 (nanobody), FOLIC ACID, ... (4 entities in total)
Functional Keywordsalpha/beta fold, immunoglobulin fold, reductase, nadph, folate derivatives, reduction, oxidoreductase-immune system complex, oxidoreductase/immune system
Biological sourceEscherichia coli
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Total number of polymer chains2
Total molecular weight33287.34
Authors
Oyen, D.,Steyaert, J.,Barlow, J.N. (deposition date: 2012-11-19, release date: 2013-11-27)
Primary citation
Oyen, D.,Steyaert, J.,Barlow, J.N.
Exploring an alternative antibody interaction mechanism
To be Published,
Experimental method
X-RAY DIFFRACTION (1.6 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.180200.9%1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution