6N13
 
 | | UbcH7-Ub Complex with R0RBR Parkin and phosphoubiquitin | | 分子名称: | E3 ubiquitin-protein ligase parkin, Ubiquitin-conjugating enzyme E2 L3, ZINC ION, ... | | 著者 | Condos, T.E.C, Dunkerley, K.M, Freeman, E.A, Barber, K.R, Aguirre, J.D, Chaugule, V.K, Xiao, Y, Konermann, L, Walden, H, Shaw, G.S. | | 登録日 | 2018-11-08 | | 公開日 | 2018-11-28 | | 最終更新日 | 2020-01-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation.
EMBO J., 37, 2018
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5C1Z
 | | Parkin (UblR0RBR) | | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ... | | 著者 | kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H. | | 登録日 | 2015-06-15 | | 公開日 | 2015-07-29 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
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5C23
 | | Parkin (S65DUblR0RBR) | | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ... | | 著者 | Kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H. | | 登録日 | 2015-06-15 | | 公開日 | 2015-07-29 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
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2LGY
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2M48
 | | Solution Structure of IBR-RING2 Tandem Domain from Parkin | | 分子名称: | E3 UBIQUITIN-PROTEIN LIGASE PARKIN, ZINC ION | | 著者 | Noh, Y.J, Mercier, P, Spratt, D.E, Shaw, G.S. | | 登録日 | 2013-01-30 | | 公開日 | 2013-05-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.
Nat Commun, 4, 2013
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2LWR
 | | Solution Structure of RING2 Domain from Parkin | | 分子名称: | SD01679p, ZINC ION | | 著者 | Mercier, P, Spratt, D.E, Manczyk, N, Shaw, G.S. | | 登録日 | 2012-08-06 | | 公開日 | 2013-06-12 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.
Nat Commun, 4, 2013
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5N2W
 | | WT-Parkin and pUB complex | | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, ... | | 著者 | Kumar, A, Chaugule, V.K, Johnson, C, Toth, R, Sundaramoorthy, R, Knebel, A, Walden, H. | | 登録日 | 2017-02-08 | | 公開日 | 2017-04-19 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.
Nat. Struct. Mol. Biol., 24, 2017
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5N38
 | | S65DParkin and pUB complex | | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, ... | | 著者 | Kumar, A, Chaugule, V.K, Johnson, C, Toth, R, Sundaramoorthy, R, Knebel, A, Walden, H. | | 登録日 | 2017-02-08 | | 公開日 | 2017-04-19 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.
Nat. Struct. Mol. Biol., 24, 2017
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1FXT
 | | STRUCTURE OF A CONJUGATING ENZYME-UBIQUITIN THIOLESTER COMPLEX | | 分子名称: | UBIQUITIN, UBIQUITIN-CONJUGATING ENZYME E2-24 KDA | | 著者 | Hamilton, K.S, Shaw, G.S, Williams, R.S, Huzil, J.T, McKenna, S, Ptak, C, Glover, M, Ellison, M.J. | | 登録日 | 2000-09-26 | | 公開日 | 2001-10-10 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail.
Structure, 9, 2001
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1FZY
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4Q5H
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4Q5E
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4DRW
 | | Crystal Structure of the Ternary Complex between S100A10, an Annexin A2 N-terminal Peptide and an AHNAK Peptide | | 分子名称: | Neuroblast differentiation-associated protein AHNAK, Protein S100-A10/Annexin A2 chimeric protein | | 著者 | Rezvanpour, A, Lee, T.-W, Junop, M.S, Shaw, G.S. | | 登録日 | 2012-02-17 | | 公開日 | 2012-10-24 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structure of an asymmetric ternary protein complex provides insight for membrane interaction.
Structure, 20, 2012
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