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4NS3
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BU of 4ns3 by Molmil
Crystal structure of the Delta-pyrroline-5-carboxylate dehydrogenase from Mycobacterium tuberculosis bound with NAD and cobalamin
Descriptor: COBALAMIN, Delta-1-pyrroline-5-carboxylate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Lagautriere, T, Bashiri, G, Baker, E.N.
Deposit date:2013-11-27
Release date:2015-01-14
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Use of a "silver bullet" to resolve crystal lattice dislocation disorder: A cobalamin complex of Delta (1)-pyrroline-5-carboxylate dehydrogenase from Mycobacterium tuberculosis.
J.Struct.Biol., 189, 2015
4P0D
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BU of 4p0d by Molmil
The T6 backbone pilin of serotype M6 Streptococcus pyogenes has a modular three-domain structure decorated with variable loops and extensions
Descriptor: CALCIUM ION, IODIDE ION, Trypsin-resistant surface T6 protein
Authors:Young, P.G, Moreland, N.J, Loh, J.M, Bell, A, Atatoa-Carr, P, Proft, T, Baker, E.N.
Deposit date:2014-02-20
Release date:2014-08-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Conservation, Variability, and Immunogenicity of the T6 Backbone Pilin of Serotype M6 Streptococcus pyogenes.
Infect.Immun., 82, 2014
4PMK
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BU of 4pmk by Molmil
Crystal structure of kiwellin
Descriptor: CHLORIDE ION, Kiwellin
Authors:Hamiaux, C, Baker, E.N, Atkinson, R.G.
Deposit date:2014-05-22
Release date:2014-08-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of kiwellin, a major cell-wall protein from kiwifruit.
J.Struct.Biol., 187, 2014
4QVH
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BU of 4qvh by Molmil
Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein
Descriptor: CITRATE ANION, COENZYME A, GLYCEROL, ...
Authors:Jung, J, Bashiri, G, Johnston, J.M, Baker, E.N.
Deposit date:2014-07-15
Release date:2014-12-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein.
J.Struct.Biol., 188, 2014
1F5J
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BU of 1f5j by Molmil
CRYSTAL STRUCTURE OF XYNB, A HIGHLY THERMOSTABLE BETA-1,4-XYLANASE FROM DICTYOGLOMUS THERMOPHILUM RT46B.1, AT 1.8 A RESOLUTION
Descriptor: BETA-1,4-XYLANASE, SULFATE ION
Authors:McCarthy, A.A, Baker, E.N.
Deposit date:2000-07-26
Release date:2000-11-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of XynB, a highly thermostable beta-1,4-xylanase from Dictyoglomus thermophilum Rt46B.1, at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 56, 2000
1H5Y
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BU of 1h5y by Molmil
HisF protein from Pyrobaculum aerophilum
Descriptor: GLYCEROL, HISF, PHOSPHATE ION
Authors:Banfield, M.J, Lott, J.S, McCarthy, A.A, Baker, E.N.
Deposit date:2001-05-31
Release date:2001-06-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Hisf, a Histidine Biosynthetic Protein from Pyrobaculum Aerophilum
Acta Crystallogr.,Sect.D, 57, 2001
1H6B
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BU of 1h6b by Molmil
Reduced Precursor Form of Glucose-Fructose Oxidoreductase from Zymomonas mobilis complexed with glycerol
Descriptor: GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PRECURSOR FORM OF GLUCOSE-FRUCTOSE OXIDOREDUCTASE
Authors:Nurizzo, D, Baker, E.N.
Deposit date:2001-06-11
Release date:2001-11-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structures of the Precursor Form of Glucose-Fructose Oxidoreductase from Zymomonas Mobilis and its Complexes with Bound Ligands
Biochemistry, 40, 2001
1H6A
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BU of 1h6a by Molmil
Reduced Precursor Form of Glucose-Fructose Oxidoreductase from Zymomonas mobilis
Descriptor: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PRECURSOR FORM OF GLUCOSE-FRUCTOSE OXIDOREDUCTASE
Authors:Nurizzo, D, Baker, E.N.
Deposit date:2001-06-11
Release date:2001-11-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of the Precursor Form of Glucose-Fructose Oxidoreductase from Zymomonas Mobilis and its Complexes with Bound Ligands(,)
Biochemistry, 40, 2001
1H6D
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BU of 1h6d by Molmil
Oxidized Precursor Form of Glucose-Fructose Oxidoreductase from Zymomonas mobilis complexed with glycerol
Descriptor: GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PRECURSOR FORM OF GLUCOSE-FRUCTOSE OXIDOREDUCTASE
Authors:Nurizzo, D, Baker, E.N.
Deposit date:2001-06-12
Release date:2001-11-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structures of the Precursor Form of Glucose-Fructose Oxidoreductase from Zymomonas Mobilis and its Complexes with Bound Ligands
Biochemistry, 40, 2001
1H6C
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BU of 1h6c by Molmil
Oxidized Precursor Form of Glucose-Fructose Oxidoreductase from Zymomonas mobilis complexed with succinate
Descriptor: GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PRECURSOR FORM OF GLUCOSE-FRUCTOSE OXIDOREDUCTASE, ...
Authors:Nurizzo, D, Baker, E.N.
Deposit date:2001-06-11
Release date:2001-11-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of the Precursor Form of Glucose-Fructose Oxidoreductase from Zymomonas Mobilis and its Complexes with Bound Ligands
Biochemistry, 40, 2001
1JBW
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BU of 1jbw by Molmil
FPGS-AMPPCP-folate complex
Descriptor: 5,10-METHYLENE-6-HYDROFOLIC ACID, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, FOLYLPOLYGLUTAMATE SYNTHASE, ...
Authors:Sun, X, Cross, J.A, Bognar, A.L, Baker, E.N, Smith, C.A.
Deposit date:2001-06-06
Release date:2001-09-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Folate-binding triggers the activation of folylpolyglutamate synthetase.
J.Mol.Biol., 310, 2001
3CQE
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BU of 3cqe by Molmil
Wee1 kinase complex with inhibitor PD074291
Descriptor: 8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole-7-carboxamide, CHLORIDE ION, GLYCEROL, ...
Authors:Squire, C.J, Baker, E.N.
Deposit date:2008-04-02
Release date:2009-02-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Determinants of Wee1 Inhibitor Selectivity
To be Published
3CR0
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BU of 3cr0 by Molmil
Wee1 kinase complex with inhibitor PD259_809
Descriptor: 4-(2-chlorophenyl)-8-(2-hydroxyethyl)-6-methylpyrrolo[3,4-e]indole-1,3(2H,6H)-dione, CHLORIDE ION, GLYCEROL, ...
Authors:Squire, C.J, Baker, E.N.
Deposit date:2008-04-03
Release date:2009-02-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural determinants of Wee1 inhibitor selectivity
To be Published
3CEV
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BU of 3cev by Molmil
ARGINASE FROM BACILLUS CALDEVELOX, COMPLEXED WITH L-ARGININE
Descriptor: ARGININE, MANGANESE (II) ION, PROTEIN (ARGINASE)
Authors:Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N.
Deposit date:1999-03-15
Release date:1999-04-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
Structure Fold.Des., 7, 1999
3DA8
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BU of 3da8 by Molmil
Crystal structure of PurN from Mycobacterium tuberculosis
Descriptor: BETA-MERCAPTOETHANOL, IODIDE ION, MAGNESIUM ION, ...
Authors:Zhang, Z, Squire, C.J, Baker, E.N.
Deposit date:2008-05-28
Release date:2009-05-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structures of glycinamide ribonucleotide transformylase (PurN) from Mycobacterium tuberculosis reveal a novel dimer with relevance to drug discovery.
J.Mol.Biol., 389, 2009
3DCJ
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BU of 3dcj by Molmil
Crystal structure of glycinamide formyltransferase (PurN) from Mycobacterium tuberculosis in complex with 5-methyl-5,6,7,8-tetrahydrofolic acid derivative
Descriptor: CHLORIDE ION, MAGNESIUM ION, N-[4-({[(6S)-2-AMINO-4-HYDROXY-5-METHYL-5,6,7,8-TETRAHYDROPTERIDIN-6-YL]METHYL}AMINO)BENZOYL]-L-GLUTAMIC ACID, ...
Authors:Zhang, Z, Squire, C.J, Baker, E.N.
Deposit date:2008-06-03
Release date:2009-05-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of glycinamide ribonucleotide transformylase (PurN) from Mycobacterium tuberculosis reveal a novel dimer with relevance to drug discovery.
J.Mol.Biol., 389, 2009
3D98
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BU of 3d98 by Molmil
Crystal structure of GlmU from Mycobacterium tuberculosis, ligand-free form
Descriptor: Bifunctional protein glmU
Authors:Zhang, Z, Squire, C.J, Baker, E.N.
Deposit date:2008-05-27
Release date:2009-03-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and function of GlmU from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 65, 2009
3D8V
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BU of 3d8v by Molmil
Crystal structure of GlmU from Mycobacterium tuberculosis in complex with uridine-diphosphate-N-acetylglucosamine
Descriptor: Bifunctional protein glmU, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
Authors:Zhang, Z, Squire, C.J, Baker, E.N.
Deposit date:2008-05-25
Release date:2009-03-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure and function of GlmU from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 65, 2009
3E8W
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BU of 3e8w by Molmil
Crystal Structure of Epiphyas postvittana Takeout 1
Descriptor: Takeout-like protein 1, Ubiquinone-8
Authors:Hamiaux, C, Stanley, D, Greenwood, D.R, Baker, E.N, Newcomb, R.D.
Deposit date:2008-08-20
Release date:2008-12-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of Epiphyas postvittana takeout 1 with bound ubiquinone supports a role as ligand carriers for takeout proteins in insects
J.Biol.Chem., 284, 2009
3E3A
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BU of 3e3a by Molmil
The Structure of Rv0554 from Mycobacterium tuberculosis
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, POSSIBLE PEROXIDASE BPOC
Authors:Johnston, J.M, Baker, E.N.
Deposit date:2008-08-06
Release date:2009-06-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and functional analysis of Rv0554 from Mycobacterium tuberculosis: testing a putative role in menaquinone biosynthesis.
Acta Crystallogr.,Sect.D, 66, 2010
3E8T
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BU of 3e8t by Molmil
Crystal Structure of Epiphyas postvittana Takeout 1
Descriptor: Takeout-like protein 1, Ubiquinone-8
Authors:Hamiaux, C, Stanley, D, Greenwood, D.R, Baker, E.N, Newcomb, R.D.
Deposit date:2008-08-20
Release date:2008-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of Epiphyas postvittana takeout 1 with bound ubiquinone supports a role as ligand carriers for takeout proteins in insects
J.Biol.Chem., 284, 2009
3F8L
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BU of 3f8l by Molmil
Crystal Structure of the Effector Domain of PhnF from Mycobacterium smegmatis
Descriptor: GLYCEROL, HTH-type transcriptional repressor phnF, SULFATE ION
Authors:Busby, J.N, Gebhard, S, Cook, G.M, Baker, E.N, Lott, S.J, Money, V.A.
Deposit date:2008-11-12
Release date:2009-11-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of PhnF, a GntR-family transcription regulator in Mycobacterium smegmatis
To be Published
3F8M
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BU of 3f8m by Molmil
Crystal Structure of PhnF from Mycobacterium smegmatis
Descriptor: GLYCEROL, GntR-family protein transcriptional regulator
Authors:Busby, J.N, Gebhard, S, Cook, G.M, Lott, S.J, Baker, E.N, Money, V.A.
Deposit date:2008-11-12
Release date:2009-11-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of PhnF, a GntR-family transcription regulator in Mycobacterium smegmatis
To be Published
3FIG
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BU of 3fig by Molmil
Crystal Structure of Leucine-bound LeuA from Mycobacterium tuberculosis
Descriptor: 2-isopropylmalate synthase, GLYCEROL, LEUCINE, ...
Authors:Koon, N, Squire, C.J, Baker, E.N.
Deposit date:2008-12-11
Release date:2008-12-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of LeuA from Mycobacterium tuberculosis, a key enzyme in leucine biosynthesis.
Proc.Natl.Acad.Sci.USA, 101, 2004
3GI1
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BU of 3gi1 by Molmil
Crystal Structure of the laminin-binding protein Lbp of Streptococcus pyogenes
Descriptor: Laminin-binding protein of group A streptococci, ZINC ION
Authors:Linke, C, Caradoc-Davies, T.T, Young, P.G, Proft, T, Baker, E.N.
Deposit date:2009-03-04
Release date:2009-08-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The laminin-binding protein Lbp from Streptococcus pyogenes is a zinc receptor
J.Bacteriol., 191, 2009

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