3CQE
Wee1 kinase complex with inhibitor PD074291
Summary for 3CQE
Entry DOI | 10.2210/pdb3cqe/pdb |
Related | 1X8B |
Descriptor | Wee1-like protein kinase, CHLORIDE ION, 8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole-7-carboxamide, ... (5 entities in total) |
Functional Keywords | kinase domain, inhibitor, transferase |
Biological source | Homo sapiens |
Cellular location | Nucleus: P30291 |
Total number of polymer chains | 1 |
Total formula weight | 32901.03 |
Authors | Squire, C.J.,Baker, E.N. (deposition date: 2008-04-02, release date: 2009-02-24, Last modification date: 2023-11-01) |
Primary citation | Squire, C.J.,Baker, E.N.,Dickson, J.M.,Ivanovic, I.,Smaill, J.,Denny, W.A.,Palmer, B.,Thompson, A. Structural Determinants of Wee1 Inhibitor Selectivity To be Published, |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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