3CQE
Wee1 kinase complex with inhibitor PD074291
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Wee1-like protein kinase | polymer | 287 | 32296.8 | 1 | UniProt (P30291) Pfam (PF00069) | Homo sapiens | Wee1A kinase, WEE1hu |
| 2 | B (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | C (A) | 8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole-7-carboxamide | non-polymer | 476.7 | 1 | Chemie (P91) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (A) | water | water | 18.0 | 49 | Chemie (HOH) |
Sequence modifications
A: 291 - 575 (UniProt: P30291)
| PDB | External Database | Details |
|---|---|---|
| Gly 289 | - | expression tag |
| Ala 290 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32296.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 604.3 | |
| All* | Total formula weight | 32901.0 |
