3CR0
Wee1 kinase complex with inhibitor PD259_809
Summary for 3CR0
Entry DOI | 10.2210/pdb3cr0/pdb |
Related | 1X8B |
Descriptor | Wee1-like protein kinase, CHLORIDE ION, 4-(2-chlorophenyl)-8-(2-hydroxyethyl)-6-methylpyrrolo[3,4-e]indole-1,3(2H,6H)-dione, ... (5 entities in total) |
Functional Keywords | kinase domain, inhibitor complex, transferase |
Biological source | Homo sapiens |
Cellular location | Nucleus: P30291 |
Total number of polymer chains | 1 |
Total formula weight | 32779.10 |
Authors | Squire, C.J.,Baker, E.N. (deposition date: 2008-04-03, release date: 2009-02-24, Last modification date: 2023-11-01) |
Primary citation | Squire, C.J.,Baker, E.N.,Dickson, J.M.,Ivanovic, I.,Smaill, J.,Denny, W.A.,Palmer, B.,Thompson, A. Structural determinants of Wee1 inhibitor selectivity To be Published, |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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