4ATY
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2W3P
| BoxC crystal structure | 分子名称: | BENZOYL-COA-DIHYDRODIOL LYASE, BETA-MERCAPTOETHANOL, GLYCEROL | 著者 | Bains, J, Boulanger, M.J. | 登録日 | 2008-11-13 | 公開日 | 2009-04-14 | 最終更新日 | 2017-07-05 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural and Biophysical Characterization of Boxc from Burkholderia Xenovorans Lb400: A Novel Ring-Cleaving Enzyme in the Crotonase Superfamily. J.Biol.Chem., 284, 2009
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2VRO
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2Y51
| Crystal structure of E167A mutant of the box pathway encoded ALDH from Burkholderia xenovorans LB400 | 分子名称: | ALDEHYDE DEHYDROGENASE (BOX PATHWAY), GLYCEROL | 著者 | Bains, J, Leon, R, Temke, K.G, Boulanger, M.J. | 登録日 | 2011-01-11 | 公開日 | 2011-06-01 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Elucidating the Reaction Mechanism of the Benzoate Oxidation Pathway Encoded Aldehyde Dehydrogenase from Burkholderia Xenovorans Lb400. Protein Sci., 20, 2011
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2XUA
| Crystal structure of the enol-lactonase from Burkholderia xenovorans LB400 | 分子名称: | 3-OXOADIPATE ENOL-LACTONASE, LAEVULINIC ACID | 著者 | Bains, J, Kaufman, L, Farnell, B, Boulanger, M.J. | 登録日 | 2010-10-17 | 公開日 | 2011-01-26 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A Product Analog Bound Form of 3-Oxoadipate-Enol- Lactonase (Pcad) Reveals a Multifunctional Role for the Divergent CAP Domain. J.Mol.Biol., 406, 2011
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2Y53
| Crystal structure of E257Q mutant of the box pathway encoded ALDH from Burkholderia xenovorans LB400 | 分子名称: | ALDEHYDE DEHYDROGENASE (BOX PATHWAY), GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Bains, J, Leon, R, Temke, K.G, Boulanger, M.J. | 登録日 | 2011-01-11 | 公開日 | 2011-06-01 | 最終更新日 | 2015-10-07 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Elucidating the Reaction Mechanism of the Benzoate Oxidation Pathway Encoded Aldehyde Dehydrogenase from Burkholderia Xenovorans Lb400. Protein Sci., 20, 2011
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2Y5D
| Crystal structure of C296A mutant of the box pathway encoded ALDH from Burkholderia xenovorans LB400 | 分子名称: | ALDEHYDE DEHYDROGENASE (BOX PATHWAY), GLYCEROL, HEXAETHYLENE GLYCOL, ... | 著者 | Bains, J, Leon, R, Temke, K.G, Boulanger, M.J. | 登録日 | 2011-01-12 | 公開日 | 2011-06-01 | 最終更新日 | 2013-01-23 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Elucidating the Reaction Mechanism of the Benzoate Oxidation Pathway Encoded Aldehyde Dehydrogenase from Burkholderia Xenovorans Lb400. Protein Sci., 20, 2011
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2Y52
| Crystal structure of E496A mutant of the box pathway encoded ALDH from Burkholderia xenovorans LB400 | 分子名称: | ALDEHYDE DEHYDROGENASE (BOX PATHWAY), GLYCEROL | 著者 | Bains, J, Leon, R, Temke, K.G, Boulanger, M.J. | 登録日 | 2011-01-11 | 公開日 | 2011-06-01 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Elucidating the Reaction Mechanism of the Benzoate Oxidation Pathway Encoded Aldehyde Dehydrogenase from Burkholderia Xenovorans Lb400. Protein Sci., 20, 2011
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2V7B
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3JPV
| Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a pyrrolo[2,3-a]carbazole ligand | 分子名称: | 1,10-dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde, Peptide (PIMTIDE) ARKRRRHPSGPPTA, Proto-oncogene serine/threonine-protein kinase Pim-1 | 著者 | Filippakopoulos, P, Bullock, A.N, Fedorov, O, Akue-Gedu, R, Rossignol, E, Azzaro, S, Bain, J, Cohen, P, Prudhomme, M, Moreau, P, Amizon, F, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2009-09-04 | 公開日 | 2009-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Synthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new pim kinase inhibitors. J.Med.Chem., 52, 2009
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1UU8
| Structure of human PDK1 kinase domain in complex with BIM-1 | 分子名称: | 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, 3-{1-[3-(DIMETHYLAMINO)PROPYL]-1H-INDOL-3-YL}-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE, GLYCEROL, ... | 著者 | Komander, D, Kular, G.S, Schuttelkopf, A.W, Deak, M, Prakash, K.R, Bain, J, Elliot, M, Garrido-Franco, M, Kozikowski, A.P, Alessi, D.R, Van Aalten, D.M.F. | 登録日 | 2003-12-16 | 公開日 | 2004-03-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Interactions of Ly333531 and Other Bisindolyl Maleimide Inhibitors with Pdk1 Structure, 12, 2004
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1UVR
| Structure of human PDK1 kinase domain in complex with BIM-8 | 分子名称: | 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, 3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1-METHYL-1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE, GLYCEROL, ... | 著者 | Komander, D, Garrido-Franco, M, Kular, G.S, Schuttelkopf, A.W, Deak, M, Prakash, K.R, Bain, J, Elliot, M, Kozikowski, A.P, Alessi, D.R, Van Aalten, D.M.F. | 登録日 | 2004-01-22 | 公開日 | 2004-03-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Interactions of Ly333531 and Other Bisindolyl Maleimide Inhibitors with Pdk1 Structure, 12, 2004
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1UU7
| Structure of human PDK1 kinase domain in complex with BIM-2 | 分子名称: | 3-(1H-INDOL-3-YL)-4-(1-{2-[(2S)-1-METHYLPYRROLIDINYL]ETHYL}-1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE, 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, GLYCEROL, ... | 著者 | Komander, D, Kular, G.S, Schuttelkopf, A.W, Deak, M, Prakash, K.R, Bain, J, Elliot, M, Garrido-Franco, M, Kozikowski, A.P, Alessi, D.R, Van Aalten, D.M.F. | 登録日 | 2003-12-16 | 公開日 | 2004-03-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Interactions of Ly333531 and Other Bisindolyl Maleimide Inhibitors with Pdk1 Structure, 12, 2004
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1UU3
| Structure of human PDK1 kinase domain in complex with LY333531 | 分子名称: | (9R)-9-[(DIMETHYLAMINO)METHYL]-6,7,10,11-TETRAHYDRO-9H,18H-5,21:12,17-DIMETHENODIBENZO[E,K]PYRROLO[3,4-H][1,4,13]OXADIA ZACYCLOHEXADECINE-18,20-DIONE, 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, GLYCEROL, ... | 著者 | Komander, D, Kular, G.S, Schuttelkopf, A.W, Deak, M, Prakash, K.R, Bain, J, Elliot, M, Garrido-Franco, M, Kozikowski, A.P, Alessi, D.R, Van Aalten, D.M.F. | 登録日 | 2003-12-15 | 公開日 | 2004-03-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Interactions of Ly333531 and Other Bisindolyl Maleimide Inhibitors with Pdk1 Structure, 12, 2004
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1UU9
| Structure of human PDK1 kinase domain in complex with BIM-3 | 分子名称: | 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, 3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE, GLYCEROL, ... | 著者 | Komander, D, Kular, G.S, Schuttelkopf, A.W, Deak, M, Prakash, K.R, Bain, J, Elliot, M, Garrido-Franco, M, Kozikowski, A.P, Alessi, D.R, Van Aalten, D.M.F. | 登録日 | 2003-12-16 | 公開日 | 2004-03-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Interactions of Ly333531 and Other Bisindolyl Maleimide Inhibitors with Pdk1 Structure, 12, 2004
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1OM1
| Crystal structure of maize CK2 alpha in complex with IQA | 分子名称: | (5-OXO-5,6-DIHYDRO-INDOLO[1,2-A]QUINAZOLIN-7-YL)-ACETIC ACID, Casein kinase II, alpha chain | 著者 | Battistutta, R, De Moliner, E, Zanotti, G. | 登録日 | 2003-02-24 | 公開日 | 2004-02-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA). Biochem.J., 374, 2003
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3PVG
| Crystal structure of Z. mays CK2 alpha subunit in complex with the inhibitor 4,5,6,7-tetrabromo-1-carboxymethylbenzimidazole (K68) | 分子名称: | (4,5,6,7-tetrabromo-1H-benzimidazol-1-yl)acetic acid, Casein kinase II subunit alpha | 著者 | Papinutto, E, Franchin, C, Battistutta, R. | 登録日 | 2010-12-07 | 公開日 | 2010-12-15 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | ATP site-directed inhibitors of protein kinase CK2: an update. Curr Top Med Chem, 11, 2011
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1OKY
| Structure of human PDK1 kinase domain in complex with staurosporine | 分子名称: | 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1, GLYCEROL, STAUROSPORINE, ... | 著者 | Komander, D, Kular, G.S, Alessi, D.R, Van Aalten, D.M.F. | 登録日 | 2003-08-01 | 公開日 | 2004-07-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis for Ucn-01 (7-Hydroxystaurosporine) Specificity and Pdk1 (3-Phosphoinositide-Dependent Protein Kinase-1) Inhibition Biochem.J., 375, 2003
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1OKZ
| Structure of human PDK1 kinase domain in complex with UCN-01 | 分子名称: | 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1, 7-HYDROXYSTAUROSPORINE, GLYCEROL, ... | 著者 | Komander, D, Kular, G.S, Alessi, D.R, Van Aalten, D.M.F. | 登録日 | 2003-08-01 | 公開日 | 2004-07-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Structural Basis for Ucn-01 (7-Hydroxystaurosporine) Specificity and Pdk1 (3-Phosphoinositide-Dependent Protein Kinase-1) Inhibition Biochem.J., 375, 2003
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3FL5
| Protein kinase CK2 in complex with the inhibitor Quinalizarin | 分子名称: | 1,2,5,8-tetrahydroxyanthracene-9,10-dione, Casein kinase II subunit alpha, DI(HYDROXYETHYL)ETHER | 著者 | Mazzorana, M, Franchin, C, Battistutta, R. | 登録日 | 2008-12-18 | 公開日 | 2009-08-18 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2 Biochem.J., 421, 2009
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3KXH
| Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor (2-dymethylammino-4,5,6,7-tetrabromobenzoimidazol-1yl-acetic acid (K66) | 分子名称: | Casein kinase II subunit alpha, DI(HYDROXYETHYL)ETHER, [4,5,6,7-tetrabromo-2-(dimethylamino)-1H-benzimidazol-1-yl]acetic acid | 著者 | Papinutto, E, Franchin, C, Battistutta, R. | 登録日 | 2009-12-03 | 公開日 | 2010-11-17 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | ATP site-directed inhibitors of protein kinase CK2: an update. Curr Top Med Chem, 11, 2011
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3KXN
| Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor tetraiodobenzimidazole (K88) | 分子名称: | 4,5,6,7-tetraiodo-1H-benzimidazole, Casein kinase II subunit alpha | 著者 | Papinutto, E, Franchin, C, Battistutta, R. | 登録日 | 2009-12-03 | 公開日 | 2010-11-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | ATP site-directed inhibitors of protein kinase CK2: an update. Curr Top Med Chem, 11, 2011
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3KXM
| Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor K74 | 分子名称: | Casein kinase II subunit alpha, N-methyl-2-[(4,5,6,7-tetrabromo-1-methyl-1H-benzimidazol-2-yl)sulfanyl]acetamide | 著者 | Papinutto, E, Franchin, C, Battistutta, R. | 登録日 | 2009-12-03 | 公開日 | 2010-11-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | ATP site-directed inhibitors of protein kinase CK2: an update. Curr Top Med Chem, 11, 2011
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3KXG
| Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor 3,4,5,6,7-pentabromo-1H-indazole (K64) | 分子名称: | 3,4,5,6,7-pentabromo-1H-indazole, Casein kinase II subunit alpha | 著者 | Papinutto, E, Franchin, C, Battistutta, R. | 登録日 | 2009-12-03 | 公開日 | 2010-11-17 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | ATP site-directed inhibitors of protein kinase CK2: an update. Curr Top Med Chem, 11, 2011
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3PE1
| Crystal structure of human protein kinase CK2 alpha subunit in complex with the inhibitor CX-4945 | 分子名称: | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, Casein kinase II subunit alpha, SULFATE ION | 著者 | Battistutta, R, Papinutto, E, Lolli, G, Pierre, F, Haddach, M, Ryckman, D.M. | 登録日 | 2010-10-25 | 公開日 | 2011-09-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer. Biochemistry, 50, 2011
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