4Q31
| The crystal structure of cystathione gamma lyase (CalE6) from Micromonospora echinospora | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FORMIC ACID, ... | 著者 | Tan, K, Bigelow, L, Jedrzejczak, R, Babnigg, G, Bingman, C.A, Yennamalli, R.M, Singh, S, Kharel, M.K, Thorson, J.S, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-04-10 | 公開日 | 2014-05-07 | 最終更新日 | 2017-03-08 | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | 主引用文献 | Structural dynamics of a methionine gamma-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate. Struct Dyn, 3, 2016
|
|
4QA9
| Ensemble refinement of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus. | 分子名称: | 1,2-ETHANEDIOL, Epoxide hydrolase, SULFATE ION | 著者 | Wang, F, Tan, K, Bigelow, L, Clancy, S, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J, Ma, M, Shen, B, Joachimiak, A, Phillips Jr, G.N, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-05-02 | 公開日 | 2014-05-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Ensemble refinement of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus. To be Published
|
|
4R82
| Streptomyces globisporus C-1027 NADH:FAD oxidoreductase SgcE6 in complex with NAD and FAD fragments | 分子名称: | ACETATE ION, CALCIUM ION, CHLORIDE ION, ... | 著者 | Tan, K, Bigelow, L, Clancy, S, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-08-29 | 公開日 | 2014-10-01 | 最終更新日 | 2016-11-02 | 実験手法 | X-RAY DIFFRACTION (1.659 Å) | 主引用文献 | Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus. Biochemistry, 55, 2016
|
|
4RAM
| Crystal Structure of New Delhi Metallo-beta-Lactamase-1 Mutant M67V Complexed with Hydrolyzed Penicillin G | 分子名称: | Beta-lactamase NDM-1, CHLORIDE ION, OPEN FORM - PENICILLIN G, ... | 著者 | Kim, Y, Tesar, C, Jedrzejczak, R, Babnigg, G, Sacchettini, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) | 登録日 | 2014-09-10 | 公開日 | 2014-09-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.495 Å) | 主引用文献 | Crystal Structure of New Delhi Metallo-beta-Lactamase-1 Mutant M67V Complexed with Hydrolyzed Penicillin G To be Published
|
|
4RBS
| Crystal Structure of New Delhi Metallo-beta-Lactamase-1 in the Complex with Hydrolyzed Meropenem | 分子名称: | (2S)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-3-methyl-2H-pyrro le-5-carboxylic acid, ACETIC ACID, Beta-lactamase NDM-1, ... | 著者 | Kim, Y, Tesar, C, Jedrzejczak, R, Babnigg, G, Sacchettini, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) | 登録日 | 2014-09-12 | 公開日 | 2014-11-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.405 Å) | 主引用文献 | Crystal Structure of New Delhi Metallo-beta-Lactamase-1 in the Complex with Hydrolyzed Meropenem To be Published
|
|
4RAW
| Crystal Structure of New Delhi Metallo-beta-Lactamase-1 Mutant M67V Complexed with Hydrolyzed Ampicillin | 分子名称: | (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase NDM-1, ... | 著者 | Kim, Y, Tesar, C, Jedrzejczak, R, Babnigg, G, Sacchettini, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) | 登録日 | 2014-09-11 | 公開日 | 2014-11-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.302 Å) | 主引用文献 | Crystal Structure of New Delhi Metallo-beta-Lactamase-1 Mutant M67V Complexed with Hydrolyzed Ampicillin To be Published
|
|
4S1W
| Structure of a putative Glutamine--Fructose-6-Phosphate Aminotransferase from Staphylococcus aureus subsp. aureus Mu50 | 分子名称: | DI(HYDROXYETHYL)ETHER, Glutamine--fructose-6-phosphate aminotransferase [isomerizing] | 著者 | Filippova, E.V, Shuvalova, L, Kiryukhina, O, Jedrzejczak, R, Babnigg, G, Rubin, E, Sacchettini, J, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) | 登録日 | 2015-01-15 | 公開日 | 2015-03-18 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structure of a putative Glutamine--Fructose-6-Phosphate Aminotransferase from Staphylococcus aureus subsp. aureus Mu50 To be Published
|
|
5TF0
| Crystal Structure of Glycosil Hydrolase Family 3 N-Terminal Domain Protein from Bacteroides intestinalis | 分子名称: | 1,2-ETHANEDIOL, Glycosyl hydrolase family 3 N-terminal domain protein, MAGNESIUM ION | 著者 | Kim, Y, Hatzos-Skintges, C, Endres, M, Babnigg, G, Joachimiak, A, MCSG, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2016-09-23 | 公開日 | 2016-10-05 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (2.2021 Å) | 主引用文献 | Crystal Structure of Glycosil Hydrolase Family 3 N-Terminal Domain Protein from Bacteroides intestinalis To Be Published, 2016
|
|
5TGF
| Crystal structure of putative beta-lactamase from Bacteroides dorei DSM 17855 | 分子名称: | CALCIUM ION, GLYCEROL, Uncharacterized protein | 著者 | Nocek, B, Hatzos-Skintges, C, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2016-09-27 | 公開日 | 2016-10-26 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Crystal structure of a beta-lactamase from Bacteroides dorei DSM 17855 To Be Published
|
|
5TFQ
| Crystal structure of a representative of class A beta-lactamase from Bacteroides cellulosilyticus DSM 14838 | 分子名称: | Beta-lactamase, GLYCEROL, PHOSPHATE ION | 著者 | Nocek, B, Hatzos-Skintges, C, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2016-09-26 | 公開日 | 2016-11-02 | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | 主引用文献 | Crystal structure of a representative of class A beta-lactamase from Bacteroides cellulosilyticus DSM 14838 To Be Published
|
|
5UC0
| Crystal Structure of Beta-barrel-like, Uncharacterized Protein of COG5400 from Brucella abortus | 分子名称: | CHLORIDE ION, PENTAETHYLENE GLYCOL, SULFATE ION, ... | 著者 | Kim, Y, Bigelow, L, Endres, M, Babnigg, G, Crosson, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2016-12-21 | 公開日 | 2017-02-08 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Periplasmic protein EipA determines envelope stress resistance and virulence in Brucella abortus. Mol. Microbiol., 2018
|
|
5UPQ
| Acyl-CoA synthetase PtmA2 from Streptomyces platensis in complex with SBNP465 ligand | 分子名称: | 5'-O-[(R)-{[(7beta,8alpha,9beta,10alpha,13alpha,16beta)-7,16-dihydroxy-18-oxokauran-18-yl]oxy}(hydroxy)phosphoryl]adenosine, Acyl-CoA synthetase PtmA2, CHLORIDE ION, ... | 著者 | Osipiuk, J, Hatzos-Skintges, C, Endres, M, Babnigg, G, Rudolf, J.D, Chang, C.Y, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2017-02-03 | 公開日 | 2017-02-22 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme. Nat. Chem. Biol., 14, 2018
|
|
5UPS
| Acyl-CoA synthetase PtmA2 from Streptomyces platensis in complex with SBNP663 ligand | 分子名称: | 5'-O-[(R)-hydroxy{[(7beta,8alpha,9beta,10alpha,11beta,13alpha)-7-hydroxy-19-oxo-11,16-epoxykauran-19-yl]oxy}phosphoryl]adenosine, Acyl-CoA synthetase PtmA2, FORMIC ACID, ... | 著者 | Osipiuk, J, Hatzos-Skintges, C, Endres, M, Babnigg, G, Rudolf, J.D, Chang, C.-Y, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2017-02-03 | 公開日 | 2017-02-22 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme. Nat. Chem. Biol., 14, 2018
|
|
5UPT
| Acyl-CoA synthetase PtmA2 from Streptomyces platensis in complex with SBNP468 ligand | 分子名称: | (7alpha,8alpha,10alpha,13alpha)-7,16-dihydroxykauran-18-oic acid, Acyl-CoA synthetase PtmA2, CHLORIDE ION, ... | 著者 | Osipiuk, J, Hatzos-Skintges, C, Endres, M, Babnigg, G, Rudolf, J.D, Chang, C.Y, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2017-02-03 | 公開日 | 2017-02-22 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme. Nat. Chem. Biol., 14, 2018
|
|
5WHM
| Crystal Structure of IclR Family Transcriptional Regulator from Brucella abortus | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, CALCIUM ION, ... | 著者 | Kim, Y, Wu, R, Tesar, C, Endres, M, Babnigg, G, Crosson, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2017-07-17 | 公開日 | 2017-08-23 | 最終更新日 | 2019-11-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Molecular control of gene expression byBrucellaBaaR, an IclR-type transcriptional repressor. J. Biol. Chem., 293, 2018
|
|
8EUA
| Structure of SARS-CoV2 PLpro bound to a covalent inhibitor | 分子名称: | Papain-like protease nsp3, SULFATE ION, ZINC ION, ... | 著者 | Mathews, I.I, Pokhrel, S, Wakatsuki, S. | 登録日 | 2022-10-18 | 公開日 | 2023-04-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2. Nat Commun, 14, 2023
|
|
4U28
| Crystal structure of apo Phosphoribosyl isomerase A from Streptomyces sviceus ATCC 29083 | 分子名称: | PHOSPHATE ION, Phosphoribosyl isomerase A | 著者 | Chang, C, Verduzco-Castro, E.A, Endres, M, Barona-Gomez, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2014-07-16 | 公開日 | 2014-07-30 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | 主引用文献 | Co-occurrence of analogous enzymes determines evolution of a novel ( beta alpha )8-isomerase sub-family after non-conserved mutations in flexible loop. Biochem. J., 473, 2016
|
|
4TX9
| Crystal structure of HisAp from Streptomyces sviceus with degraded ProFAR | 分子名称: | AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, Phosphoribosyl isomerase A, SULFATE ION | 著者 | Michalska, K, Verduzco-Castro, E.A, Endres, M, Barona-Gomez, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2014-07-02 | 公開日 | 2014-08-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Co-occurrence of analogous enzymes determines evolution of a novel ( beta alpha )8-isomerase sub-family after non-conserved mutations in flexible loop. Biochem. J., 473, 2016
|
|
4W9T
| Crystal structure of HisAP from Streptomyces sp. Mg1 | 分子名称: | Phosphoribosyl isomerase A, SULFATE ION | 著者 | MICHALSKA, K, VERDUZCO-CASTRO, E.A, ENDRES, M, BARONA-GOMEZ, F, JOACHIMIAK, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2014-08-27 | 公開日 | 2014-09-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Co-occurrence of analogous enzymes determines evolution of a novel ( beta alpha )8-isomerase sub-family after non-conserved mutations in flexible loop. Biochem. J., 473, 2016
|
|
3U1B
| Crystal structure of the S238R mutant of mycrocine immunity protein (MccF) with AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, Microcin immunity protein MccF | 著者 | Nocek, B, Gu, M, Zhou, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2011-09-29 | 公開日 | 2011-11-30 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.604 Å) | 主引用文献 | Structural and Functional Characterization of Microcin C Resistance Peptidase MccF from Bacillus anthracis. J.Mol.Biol., 420, 2012
|
|
3TYX
| Crystal structure of the F177S mutant of mycrocine immunity protein (MccF) with AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, Microcin immunity protein MccF | 著者 | Nocek, B, Gu, M, Zhou, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2011-09-26 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Structural and Functional Characterization of Microcin C Resistance Peptidase MccF from Bacillus anthracis. J.Mol.Biol., 420, 2012
|
|
6BBX
| Crystal structure of TnmS3 in complex with TNM C | 分子名称: | Glyoxalase/bleomycin resisance protein/dioxygenase, methyl (2R,3R)-2,3-dihydroxy-3-[(1aS,11S,11aR,14Z,18R)-3,7,8,18-tetrahydroxy-4,9-dioxo-4,9,10,11-tetrahydro-11aH-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinolin-11a-yl]butanoate | 著者 | Chang, C.Y, Chang, C, Nocek, B, Rudolf, J.D, Joachimiak, A, Phillips Jr, G.N, Shen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG) | 登録日 | 2017-10-19 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Resistance to Enediyne Antitumor Antibiotics by Sequestration. Cell Chem Biol, 25, 2018
|
|
6WN5
| 1.52 Angstrom Resolution Crystal Structure of Transcriptional Regulator HdfR from Klebsiella pneumoniae | 分子名称: | CHLORIDE ION, Transcriptional regulator HdfR | 著者 | Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-04-22 | 公開日 | 2020-05-06 | 最終更新日 | 2023-06-14 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | A Structural Systems Biology Approach to High-Risk CG23 Klebsiella pneumoniae. Microbiol Resour Announc, 12, 2023
|
|
6WN8
| 2.70 Angstrom Resolution Crystal Structure of Uracil Phosphoribosyl Transferase from Klebsiella pneumoniae | 分子名称: | CHLORIDE ION, SULFATE ION, Uracil phosphoribosyltransferase, ... | 著者 | Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-04-22 | 公開日 | 2020-05-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A Structural Systems Biology Approach to High-Risk CG23 Klebsiella pneumoniae. Microbiol Resour Announc, 12, 2023
|
|
6DUX
| 2.25 Angstrom Resolution Crystal Structure of 6-phospho-alpha-glucosidase from Klebsiella pneumoniae in Complex with NAD. | 分子名称: | (2S)-2-hydroxybutanedioic acid, 6-phospho-alpha-glucosidase, ACETATE ION, ... | 著者 | Minasov, G, Shuvalova, L, Kiryukhina, O, Endres, M, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-06-22 | 公開日 | 2018-07-04 | 最終更新日 | 2023-06-14 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | A Structural Systems Biology Approach to High-Risk CG23 Klebsiella pneumoniae. Microbiol Resour Announc, 12, 2023
|
|