4RBS

Crystal Structure of New Delhi Metallo-beta-Lactamase-1 in the Complex with Hydrolyzed Meropenem

Summary for 4RBS

• Entry DOI: 10.2210/pdb4rbs/pdb
• Related: 3RKJ 3RKK 3SBL 3SFP 3SRX 4GYQ 4GYU 4H0D 4HKY 4HL1 4HL2 4RAM 4RAW
• Descriptor: Beta-lactamase NDM-1, ZINC ION, (2S)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-3-methyl-2H-pyrro le-5-carboxylic acid, ... (6 entities in total)
• Functional Keywords: structural genomics, psi-biology, midwest center for structural genomics, mcsg, structures of mtb proteins conferring susceptibility to known mtb inhibitors, mtbi, alpha-beta-beta-alpha sandwich, hydrolase
• Biological source: Klebsiella pneumoniae
• Cellular location: Periplasm : C7C422
• Total number of polymer chains: 2
• Total formula weight: 53012.88

Authors

Kim, Y.,Tesar, C.,Jedrzejczak, R.,Babnigg, G.,Sacchettini, J.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG),Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) (deposition date: 2014-09-12, release date: 2014-11-26, Last modification date: 2023-09-20)

• Primary citation: Kim, Y.,Tesar, C.,Jedrzejczak, R.,Babnigg, G.,Sacchettini, J.,Joachimiak, A.; Crystal Structure of New Delhi Metallo-beta-Lactamase-1 in the Complex with Hydrolyzed Meropenem; To be Published,

Experimental method

X-RAY DIFFRACTION (2.405 Å)